No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

BioPlantarum Plus Sterols Ingredients & Drug Interactions

by BioCare

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

BioPlantarum Plus Sterols is a dietary supplement by BioCare with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health support, lowering ldl cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of BioPlantarum Plus Sterols by BioCare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Plant Sterols” is listed as a grouped ingredient — the label gives one combined amount (800 mg) without saying how much of each component you get.

This product has 2 active ingredients: beta-sitosterol (a plant-derived sterol) and Lactobacillus plantarum CUL-66 (a probiotic microbe). Beta-sitosterol is one of the plant sterols that the product is built around.

The inactive ingredients are capsule materials and fillers like microcrystalline cellulose and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: plant sterols for healthy cholesterol levels.
  • We looked for evidence on: Hypercholesterolemia, Familial hypercholesterolemia, Coronary heart disease (CHD), Myocardial infarction (MI), Metabolic syndrome, high cholesterol — and 2 related terms.
  • The strongest evidence on file: Beta-sitosterol is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Beta-sitosterol is rated "Possibly Effective" for Familial hypercholesterolemia.

Beta-sitosterol is likely effective for benign prostatic hyperplasia (enlarged prostate). The evidence suggests it may help with familial hypercholesterolemia (inherited high cholesterol) and coronary heart disease, though those ratings are based on less robust data.

We hold no effectiveness information for Lactobacillus plantarum CUL-66 in our data, so we can't tell you whether that probiotic strain has proven benefits for any condition.

The evidence, ingredient by ingredient Plant Sterols Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-sitosterol is generally well tolerated when taken by mouth for short periods. The most common side effects are digestive: constipation, diarrhea, gas, indigestion, and nausea.

Some people may also experience reduced appetite. There's one case report of acute pancreatitis linked to beta-sitosterol, though symptoms stopped when the person quit taking it.

Acne may worsen if you take beta-sitosterol on its own. There isn't enough safety data to recommend this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist if you're pregnant or nursing and thinking about using it.

Side effects, ingredient by ingredient Plant Sterols Beta-sitosterol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check. We do not hold interaction data for Lactobacillus plantarum CUL-66, so use the medication checker below with your current prescriptions to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may be worth considering if you're looking for prostate support or want to help manage cholesterol with a plant sterol supplement. If you're pregnant, breastfeeding, have a history of pancreatitis, or take any medications regularly, check with your pharmacist first.

Digestive side effects are common, so start with the lowest dose if your stomach's sensitive.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioPlantarum Plus Sterols, straight from the product label.

Brand BioCare
Barcode (UPC) 5033290553906
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 309732
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioPlantarum Plus Sterols by BioCare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
UPC/BARCODE
5033290553906
IngredientAmount% DV
Plant Sterols800 mg--
Beta-Sitosterol320 mg--
Lactobacillus plantarum CUL-6650 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate, Lactobacillus plantarum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: 3 capsules taken daily with food, or as professionally directed.

Precautions

This product should not be used as a substitute for a varied diet and healthy lifestyle. Do not exceed the stated recommended daily intake. Do not purchase if the seal is broken.

Keep out of reach of children. Not to be taken by pregnant and breastfeeding women or children under 5 years.

If you are under medical supervision, please consult a doctor before use.

If you are taking cholesterol lowering medication, seek medical advice before taking this product. Not to be taken by pregnant and breastfeeding women or children under 5 years.

Total dietary intake (from foods and supplements) of phytosterols should not exceed 3g/day.

Storage

Store in a cool, dry place. Avoid direct sunlight and heat. Contains a desiccant to absorb moisture. we recommend that you keep this in the jar. No need to refrigerate

Formula

Plant sterols for healthy cholesterol levels with 10 billion Lactobacillus plantarum live bacteria Plant sterols contribute to the maintenance of normal blood cholesterol levels with a daily intake of at least 800mg plant sterols.

FDA Statement of Identity

Food Supplement

Formulation

For your cholesterol

Vegetarian & vegan

See for yourself

BioPlantarum Plus Sterols by BioCare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BioPlantarum Plus Sterols by BioCare

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Plant Sterols

No known
interactions
800 mg per serving

Plant sterols (and their close relatives, plant stanols) are natural compounds found in plants that can modestly lower LDL ('bad') cholesterol when ta...

Plant Sterols monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Silicon Dioxide, Magnesium Stearate, Lactobacillus plantarum. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioPlantarum Plus Sterols by BioCare Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in BioPlantarum Plus Sterols. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for BioPlantarum Plus Sterols, from the product label.

BioCare

See all BioCare products
Name
UK - BioCare Ltd
Street Address
1 Hedera Road
State
Redditch
ZipCode
B98 9EY
Phone Number
+44 0121 433 3727
Web Address
www.biocare.co.uk
Pharmacist Counseling Corner

BioPlantarum Plus Sterols by BioCare: Common Questions

Does BioPlantarum Plus Sterols by BioCare interact with any medications?
We do not currently list a known interaction for the mapped ingredients in BioPlantarum Plus Sterols. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
BioPlantarum Plus Sterols contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta-sitosterol do?
Beta-sitosterol is a plant sterol that's likely to help with enlarged prostate (benign prostatic hyperplasia). It may also help support cholesterol levels and heart health, though that evidence is less established.
What side effects might I get from beta-sitosterol?
The most common ones are digestive: constipation, diarrhea, gas, indigestion, nausea, and reduced appetite. In rare cases, acne can worsen. One case report noted acute pancreatitis, though that's very uncommon.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to recommend it during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in those situations.
What is Lactobacillus plantarum in this product?
It's a beneficial bacteria strain — a probiotic. We don't hold effectiveness or safety data for this particular strain, so we can't tell you what it's meant to do in this formula.
Do I need to worry about interactions with my medications?
No interactions are documented for beta-sitosterol. We can't check the probiotic strain, so use the search tool on this page with your current medications to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioPlantarum Plus Sterols is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioPlantarum Plus Sterols label
Sources

Sources & How We Checked

BioPlantarum Plus Sterols's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Plant Sterols 3 references
  1. Guardamagna, O., Abello, F., Baracco, V., Federici, G., Bertucci, P., Mozzi, A., Mannucci, L., Gnasso, A., and Cortese, C. Primary hyperlipidemias in children: effect of plant sterol supplementation on plasma lipids and markers of cholesterol synthesis a
  2. Haque Hussain SS, Weir J, Roberts N. Severe dermatitis secondary to plant sterol supplements. Clin Exp Dermatol. 2009 Oct;34(7):e276-7. PubMed
  3. Xue P, Wang Y, Chen Y, et al. A Case of Peripheral Precocious Puberty May Be Caused by a Diet Containing Phytosterols in a 20-Month-Old Boy. Horm Res Paediatr 2022;95(5):484-491. PubMed

See these in context on the Plant Sterols monograph →

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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