No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 5000 mcg Ingredients & Drug Interactions

by GNC

Biotin 5000 mcg label
See full label image
Capsule Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Biotin 5000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Biotin 5000 mcg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Biotin 5000 mcg by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin your body needs to break down and use nutrients from food. At 5000 mcg per capsule, this is a high-dose supplement — much more than you'd get from most foods or a standard multivitamin.

The capsule itself is made from gelatin and cellulose (an inactive filler).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports healthy hair, skin and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, hair loss, nail health, skin condition.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency — a shortage that can cause hair thinning, skin problems, or nerve damage. However, the evidence doesn't support its use for multiple sclerosis or seborrheic dermatitis (a type of itchy, flaky skin rash), where it rates possibly ineffective.

For alopecia areata (a condition causing patchy hair loss), the evidence is too limited to say whether it helps.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body clears the excess through urine. High-dose biotin has rarely caused mild diarrhea — a small number of people taking very large doses reported transient mild diarrhea.

There is one isolated case report of a 76-year-old woman who developed inflammation around the heart and lungs after taking biotin plus other supplements, but whether biotin was the culprit remains unclear, and no similar cases have been reported since. Talk with your doctor before starting a high-dose biotin supplement, especially if you have any ongoing health conditions.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you have a biotin deficiency or want to supplement for general hair and nail health, this product is likely well tolerated at the 5000 mcg dose. But check with your doctor first if you have heart, lung, or immune conditions, or if you're taking multiple supplements.

No interactions are documented for the medications we checked, but your own healthcare provider should review your full medication list before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 5000 mcg, straight from the product label.

Brand GNC
Barcode (UPC) 048107121600
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2017
DSLD ID 75076
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 5000 mcg by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
048107121600
IngredientAmount% DV
Biotin5000 mcg1667%

Other ingredients: Cellulose, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Storage

Store in a cool, dry place.

General Statements

Actual size

Supports healthy hair, skin & nails

Potency verified by GNC procedure #5003. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

FDA Statement of Identity

Dietary Supplement

General

CODE 289414 BRG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one capsule daily.

Formulation

No sugar, no starch, no artificial colors, no artificial flavors, sodium free, no wheat, gluten free, no corn, no soy, no dairy, yeast free.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Biotin 5000 mcg by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Biotin 5000 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Biotin 5000 mcg by GNC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Biotin

No known
interactions
5000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Cellulose, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 5000 mcg by GNC Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 5000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 5000 mcg, from the product label.

GNC

See all GNC products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Biotin 5000 mcg by GNC: Common Questions

Does Biotin 5000 mcg by GNC interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 5000 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 5000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or nursing?
Biotin is rated likely safe during pregnancy and lactation. That said, amounts from food and prenatal vitamins are the standard approach — talk with your doctor or midwife before taking a high-dose supplement like this one.
What exactly is biotin, and why do I need it?
Biotin is a B vitamin that helps your body convert food into energy and supports the health of your hair, skin, and nails. Your body can't make it, so you need to get it from food or supplements.
Will this actually help my hair grow or my nails get stronger?
Biotin is proven to treat biotin deficiency. For general hair and nail health in people who aren't deficient, the evidence isn't strong enough to say it works — but many people take it anyway hoping for a benefit.
Is 5000 mcg a lot?
Yes — that's much higher than you'd get from food or a standard multivitamin. At this dose, check with your doctor before starting, especially if you have any health conditions or take multiple supplements.
Are there any side effects?
High-dose biotin has rarely caused mild diarrhea. One very rare case report linked a combination of biotin and other supplements to inflammation around the heart, but that's extremely isolated and may not have been biotin's fault.
Will this interfere with any of my medications?
No interactions are documented in our data. That said, use the search tool on this page to check your specific medications, and ask your doctor or pharmacist before adding any high-dose supplement to your routine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 5000 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 5000 mcg label
Go deeper

The Full Monographs Behind Biotin 5000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph →
Sources

Sources & How We Checked

Biotin 5000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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