No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 600 Ingredients & Drug Interactions

by GNC

Biotin 600 label
See full label image
Other (e.g. Tea Bag) Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Biotin 600 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Biotin 600 is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Biotin 600 by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: biotin, a B vitamin your body needs to convert food into energy and support healthy skin, hair, and nails. The inactive ingredients are dicalcium phosphate and cellulose, which are a calcium-containing binder and a filler.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Biotin's overall clinical evidence instead.

Strong

Strong clinical evidence supports Biotin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Biotin deficiency — rated "Likely Effective" (Natural Medicines).

Biotin is likely effective for biotin deficiency — the condition your doctor would catch with a blood test if your levels are too low. For multiple sclerosis and seborrheic dermatitis (a scaly skin condition), the evidence suggests it's possibly ineffective.

For alopecia areata (patchy hair loss), we don't have enough reliable evidence to say whether it works.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at higher doses, because your body excretes what it doesn't use in your urine. High-dose biotin has rarely been linked to mild diarrhea — a small number of people taking very high amounts reported transient mild loose stools.

One isolated case report described a serious reaction, but whether biotin was actually the cause or whether it was something else the patient was taking remains unclear, and no similar cases have been reported since. Normal dietary amounts and typical supplement doses are considered likely safe in pregnancy and lactation.

However, if you're pregnant, nursing, or considering high-dose biotin supplements, talk with your doctor first to make sure it's right for you.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for biotin with any medications. That doesn't mean you shouldn't ask your pharmacist — it's always good practice to confirm before you start any new supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This product is straightforward: it delivers biotin, a B vitamin that's definitely useful if you have a biotin deficiency and generally well tolerated at standard doses. If you're taking it for hair, skin, or nails without a diagnosed deficiency, the evidence for those uses is weak or missing.

Check with your doctor or pharmacist before starting, especially if you're pregnant, nursing, or considering high doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 600, straight from the product label.

Brand GNC
Barcode (UPC) 048107027186
Net contents 120 Caplet(s)
Market status On market
Date entered into DSLD Oct 26, 2011
DSLD ID 1435
Product type Vitamin
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 600 by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
UPC/BARCODE
048107027186
IngredientAmount% DV
Biotin600 mcg200%

Other ingredients: Dicalcium Phosphate, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formulation

No Sugar, No Starch, No Artificial Colors, No Artificial Flavors, No Preservatives, Sodium Free, No Wheat, No Gluten, No Corn, No Soy, No Diary, Yeast Free.

Precautions

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry place.

General Statements

600 mcg

ACTUAL SIZE

For more information:

Lot No./Best By:

Potency verified by GNC procedure #5003. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

SHOP NOW

supports healthy hair, skin and nails

General

CODE 124811 JJG

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one caplet daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Biotin 600 by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Biotin 600 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Biotin 600 by GNC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Biotin

No known
interactions
600 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 600 by GNC Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 600. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 600, from the product label.

GNC

See all GNC products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Biotin 600 by GNC: Common Questions

Does Biotin 600 by GNC interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 600. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 600 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
Biotin is rated likely safe in pregnancy and lactation at normal dietary and supplement amounts. If you're thinking about a high-dose product like this one, talk with your doctor first to confirm it's appropriate for you.
Will biotin help my hair grow or improve my skin?
The evidence for biotin to help with hair loss or skin conditions is weak or absent in our data. It's clearly helpful if you have an actual biotin deficiency, but for cosmetic uses, the science doesn't back it up yet.
What are the side effects?
Biotin is rarely associated with side effects. High-dose biotin has occasionally been linked to mild diarrhea, and there's one old case report of a serious reaction, but that case involved other medications and it's unclear whether biotin was actually responsible.
How does biotin work?
Biotin is a B vitamin that helps your body break down food into energy and supports the health of your skin, hair, and nails. Your body uses what it needs and clears the rest through urine.
Is biotin safe to take long-term?
Biotin is generally well tolerated over time because excess amounts are excreted. That said, if you're considering long-term high-dose supplements, check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 600 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 600 label
Go deeper

The Full Monographs Behind Biotin 600’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph →
Sources

Sources & How We Checked

Biotin 600's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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