Biotin Plus Ingredients & Drug Interactions
by GNC Women's
What is this page for?
First and foremost: checking Biotin Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Biotin Plus is a dietary supplement by GNC Women's with 3 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Biotin Plus by GNC Women's
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has three active ingredients. Biotin is a B vitamin that supports hair, skin, and nail health.
Hydrolyzed collagen is a form of collagen protein that breaks down easily for absorption—your body uses it as building material for skin and connective tissue. Hyaluronic acid is a natural compound found in your body that holds moisture in the skin and eyes.
The remaining ingredients are inactive—cellulose, gelatin, stearic acid, dicalcium phosphate, magnesium stearate, silicon dioxide, titanium dioxide, and mica—which serve as fillers, binders, and capsule material.
Does it work?
Strong evidence
Biotin is likely effective for biotin deficiency, though most people get enough from food. For hair loss (alopecia areata), seborrheic dermatitis, and multiple sclerosis, the evidence isn't strong enough to say it works.
Hydrolyzed collagen is possibly effective for aging skin and dry skin, but evidence that it boosts muscle strength is weak. Hyaluronic acid is possibly effective for dry eye and may help with venous leg ulcers, though evidence for aging skin isn't established yet.
The evidence for some of these uses is still limited, so talk to your pharmacist about what you're hoping this product will do.
How safe is it?
Well-documented data
All three ingredients are generally well tolerated. Biotin is considered safe even at fairly high doses because your body removes excess through urine, though high-dose biotin has rarely caused mild diarrhea.
Hydrolyzed collagen may occasionally cause nausea, stomach upset, diarrhea, or gas, but these are uncommon. Hyaluronic acid appears well tolerated when taken by mouth, though long-term safety of oral supplements isn't fully studied.
During pregnancy, biotin is likely safe. However, hydrolyzed collagen and hyaluronic acid haven't been well studied in pregnancy or while breastfeeding—talk with your doctor before using if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a reasonable choice if you're looking to support skin, hair, and nail health with ingredients that are generally well tolerated and have at least some evidence behind them. If you're pregnant, nursing, or taking medications, check with your pharmacist first—especially about the hyaluronic acid component, which the safety data advises discussing with your doctor.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Biotin Plus, straight from the product label.
| Brand | GNC Women's |
|---|---|
| Barcode (UPC) | 048107176501 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 22, 2017 |
| DSLD ID | 81929 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult Female (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Biotin Plus by GNC Women's, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Biotin | 2000 mcg | 6667% |
| hydrolyzed Collagen | 500 mg | -- |
| Hyaluronic Acid | 10 mg | -- |
Other ingredients: Cellulose, Gelatin, Stearic Acid, Dicalcium Phosphate, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, Mica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Statement of Identity
Dietary Supplement
Formula
Features 2000 mcg of biotin
Biotin for healthy hair, skin & nails Collagen to support skin structure
General
CODE 563412 BSG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take two capsules daily with food.
General Statements
Conforms to USP <2091> for weight. Meets USP <2040> disintegration.
Seals/Symbols
Gf Gluten free
Formulation
No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, sodium free, no wheat, gluten free, no corn, no soy, no dairy, yeast free.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Biotin Plus by GNC Women's label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Biotin Plus by GNC Women's
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Biotin
No knowninteractions
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...
Biotin monograph & interactionsHydrolyzed Collagen
No knowninteractions
Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is...
Hydrolyzed Collagen monograph & interactionsHyaluronic Acid
No knowninteractions
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...
Hyaluronic Acid monograph & interactionsOther (inactive) ingredients: Cellulose, Gelatin, Stearic Acid, Dicalcium Phosphate, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, Mica. These complete the product’s ingredient list but are not active constituents.
Biotin Plus by GNC Women's Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Biotin Plus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Biotin Plus, from the product label.
GNC Women's
See all GNC Women's products- Name
- General Nutrition Corporation
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- www.gnc.com
Biotin Plus by GNC Women's: Common Questions
Does Biotin Plus by GNC Women's interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will biotin help my hair grow back?
Can I take this while I'm pregnant?
Can I breastfeed while taking this?
What side effects might I get?
Does this product have fillers?
Will this help with dry skin?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Biotin Plus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Biotin Plus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Biotin
Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...
Read the full Biotin monograph → Herb & supplement monographCollagen Peptides
Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...
Read the full Collagen Peptides monograph → Herb & supplement monographHyaluronic Acid
Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...
Read the full Hyaluronic Acid monograph →Sources & How We Checked
Biotin Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 10 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Biotin 4 references
- Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
- Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed
Collagen Peptides 2 references
- Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
- Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed
Hyaluronic Acid 4 references
- Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
- U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
- Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
- Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC