Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Bone, Beauty and Hormone Formula Ingredients & Drug Interactions

by GNC Women's

Bone, Beauty and Hormone Formula label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bone, Beauty and Hormone Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bone, Beauty and Hormone Formula is a dietary supplement by GNC Women's with 3 active ingredients. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bone, Beauty and Hormone Formula by GNC Women's

Ask about any prescription or over-the-counter medication and we check it for interactions with Bone, Beauty and Hormone Formula by GNC Women's — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bone, Beauty and Hormone Formula by GNC Women's

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains three active ingredients. Burdock root extract has a long history of use in traditional medicine.

Gamma-Linolenic Acid is a fatty acid your body uses for cell structure and function. MBP is also included, though its specific role in this formula isn't detailed in our data.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Burdock's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: bone, beauty and hormone support.
  • We looked for evidence on: Acne, Aging skin, Atopic dermatitis (eczema), Dry skin, Skin health, Hair and nails — and 1 related terms.
  • The closest evidence on file: Burdock is rated "Insufficient Reliable Evidence To Rate" for Acne (Natural Medicines).
  • Also on file: Burdock is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Atopic dermatitis (eczema), Dry skin.

The evidence for burdock root in this formula isn't yet established. Our data rates it as having insufficient reliable evidence for acne, aging skin, breast cancer, common cold, and eczema — the conditions burdock is commonly studied for.

This doesn't mean it doesn't work; it means large, well-designed human trials haven't yet proven its benefit for these uses. Effectiveness data for Gamma-Linolenic Acid and MBP in this product aren't on file.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when used as a food or taken short-term by healthy adults, though human safety data remain limited. Allergic reactions are rare but possible, including contact dermatitis (skin rash) and in very rare cases anaphylaxis.

One case of liver damage has been reported after long-term use of a burdock-containing herbal tea, though it's unclear whether burdock alone was responsible, given other ingredients were present. Burdock should not be used in medicinal amounts during pregnancy due to lack of safety data and possible effects on the uterus.

Avoid it while breastfeeding as well — there isn't enough safety information. Safety data for Gamma-Linolenic Acid and MBP during pregnancy and breastfeeding aren't on file.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take any blood thinners or antiplatelet drugs — burdock root extract may theoretically increase bleeding risk. Use the search tool on this page to confirm your exact prescriptions are clear.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may work for some people, but the evidence for burdock isn't yet strong. If you take blood thinners or antiplatelet drugs, check with your doctor or pharmacist first — that's the main interaction to watch.

Burdock is generally tolerated but rare allergic reactions can happen. If you're pregnant or breastfeeding, skip this product or talk with your doctor before taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bone, Beauty and Hormone Formula, straight from the product label.

Brand GNC Women's
Net contents 30 Pack(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243678
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bone, Beauty and Hormone Formula by GNC Women's, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel Capsule(s)
Maximum serving Sizes:
1 Softgel Capsule(s)
Servings per container
30
IngredientAmount% DV
Calories5 Calorie(s)--
Total Fat0.5 Gram(s)1%
Gamma-Linolenic Acid250 mg--
Burdock root extract100 mg--
MBP40 mg--

Other ingredients: Safflower Oil, Gelatin, Glycerin, yellow Beeswax, Silicon Dioxide, Annatto color, Soy Lecithin, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take contents of one packet daily with food. For maximum benefits, take as directed every day.

General Statements

Each Pack Contains: Bone, Beauty and Hormone Formula

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you are not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days, and we'll either refund your money or find a replacement product that is right for you.

30-Day Supply

Precautions

Contains: Milk and Soybeans.

Keep out of reach of children.

Warning: Cancer and reproductive harm - www.p65Warnings.ca.gov.

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Formulation

Conforms to USP <2091> for weight. Meets USP <2040> for disintegration.

Targeted solutions for head-to-toe support

Comprehensive support made convenient. With a multivitamin blend clinically proven to make you feel better, plus targeted solutions for head-to-toe support, our Women's Vitapak Program Whole Body has you covered.

In a randomized, double-blind, placebo-controlled study of 112 healthy volunteers, subjects taking the GNC vitamin and mineral blends for six weeks experienced significant improvements in serum levels of certain key nutrients compared to a placebo and a basic multivitamin formula based upon multivariate statistical analysis of a group of B-vitamins (thiamin, niacin, riboflavin, pantothenic acid, biotin, folic acid, and vitamins B-6 and B-12) and key antioxidants and cartenoids (a group of beta-carotene, alpha-tocopherol, selenium, lutein, lycopene). Statistical improvements in SF-36 Vitality and Mental Health scores were also observed compared to placebo. In a 12 week multi-center, randomized, double-blind, placebo-controlled study of 60 adults, subjects taking 250mg/day of the joint blend showed a significant 29.8% improvement in joint flexibility and a 19.4% improvement in joint function in 30 days compared to subjects on placebo.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

MBP is registered in the U.S.A by MegMilk Snow Brand Co., Ltd.

Formula

Includes multivitamin + heart & eye health + brain health + joint health + bone, beauty & hormone formula + antioxidant & circulation + digestive enzymes

Your added support includes: Joint & Bone Health Includes a blend clinically shown to provide a 30% improvement in flexibility and 19% improvement in joint function plus it has MBP, which is clinically studied to support the body's natural ability to build and maintain healthy bones. Beauty and Hormonal Balance GLA provides support for normal, healthy skin and hormonal balance

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bone, Beauty and Hormone Formula by GNC Women's label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bone, Beauty and Hormone Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bone, Beauty and Hormone Formula by GNC Women's

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel Capsule(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gamma-Linolenic Acid

250 mg per serving

Burdock root extract

Interacts with
122 drugs
100 mg per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock root extract monograph & interactions

MBP

40 mg per serving

Other (inactive) ingredients: Safflower Oil, Gelatin, Glycerin, Yellow Beeswax, Silicon Dioxide, Annatto color, Soy Lecithin, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bone, Beauty and Hormone Formula by GNC Women's Drug Interactions

Want to check YOUR meds against Bone, Beauty and Hormone Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock root extract 122

Individual Drug Interactions

The ingredients in Bone, Beauty and Hormone Formula interact with 122 drugs. Click any drug to see the details.

1 of the 3 ingredients in Bone, Beauty and Hormone Formula interact with drugs. Each result below shows which ingredient is responsible. Burdock root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bone, Beauty and Hormone Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock root extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bone, Beauty and Hormone Formula, from the product label.

GNC Women's

See all GNC Women's products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Bone, Beauty and Hormone Formula by GNC Women's: Common Questions

Does Bone, Beauty and Hormone Formula by GNC Women's interact with any medications?
Yes. Based on its ingredients, Bone, Beauty and Hormone Formula has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bone, Beauty and Hormone Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
No. Burdock root extract should not be used in medicinal amounts during pregnancy because safety data are lacking and it may affect the uterus. Talk with your doctor or pharmacist before considering any supplement during pregnancy.
Can I take this while breastfeeding?
No. There isn't enough safety information for medicinal use of burdock while breastfeeding. Discuss this with your doctor or pharmacist if you're interested.
What is burdock root and why is it in here?
Burdock is a plant root used traditionally in herbal medicine. It's included in this formula because it's historically associated with skin and general wellness, though scientific evidence for its benefits is still developing.
Does burdock cause side effects?
Most people tolerate burdock well, especially at food levels. Rare allergic reactions — including rashes and very rarely anaphylaxis — have been reported. One case of liver damage occurred after long-term use of a multi-ingredient herbal product containing burdock, though it's unclear if burdock was the cause.
Is this product proven to work?
Evidence isn't yet strong. Our data rates burdock as having insufficient reliable evidence for acne, aging skin, and other conditions this product targets. This doesn't mean it won't help you — it means larger human studies are needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bone, Beauty and Hormone Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bone, Beauty and Hormone Formula label
Go deeper

The Full Monographs Behind Bone, Beauty and Hormone Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Bone, Beauty and Hormone Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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