No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Bone Maker with Bonolive Olive Leaf Extract 250 mg Ingredients & Drug Interactions

by Doctor's Best

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Bone Maker with Bonolive Olive Leaf Extract 250 mg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Bonolive, a concentrated olive leaf extract at 250 mg per capsule. Olive leaf has been studied for bone health, digestive comfort, and immune support, though the evidence for those uses remains preliminary.

The capsule also includes inactive ingredients—hypromellose (a capsule material), rice hull concentrate, and stearic acid (a binder).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Olive's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: bone health and bone density support.
  • We looked for evidence on: Osteoporosis, bone loss, age-related bone density decline, fracture prevention.
  • The closest evidence on file: Olive is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis (Natural Medicines).

The evidence for Bonolive in osteoporosis, indigestion (dyspepsia), exercise-related respiratory infections, shingles, flu, and osteoarthritis is currently insufficient to rate. We don't have reliable data yet showing whether this ingredient works for any of those purposes.

If bone health is your goal, talk with your doctor about what the evidence actually supports for you.

The evidence, ingredient by ingredient Olive

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive leaf extract appears to be well tolerated in the trials we have data for. The most commonly reported side effects were headache and stomach discomfort; one person reported skin issues and acne.

Olive as food and olive oil are very safe, but concentrated supplements like this one have been studied less. If you're pregnant or nursing, we don't have safety data on file for this ingredient—talk with your doctor or pharmacist before starting it.

One more note: olive tree pollen can trigger seasonal allergies in sensitive people, though that's typically a concern for pollen exposure rather than the extract itself.

Side effects, ingredient by ingredient Olive

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Still run your medications through the tool on this page to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This product is a single-ingredient supplement with no documented drug interactions, making it straightforward from a medication standpoint. The catch is that evidence for what it actually does is still unclear, and concentrated olive leaf supplements haven't been as well studied as the food forms.

If you're considering it for bone health or another specific reason, check with your pharmacist about whether the evidence supports your goal.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bone Maker with Bonolive Olive Leaf Extract 250 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950004207
Net contents 60 Veggie Cap(s)
Market status On market
Date entered into DSLD Nov 21, 2019
DSLD ID 209382
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
753950004207
IngredientAmount% DV
Bonolive250 mg--

Other ingredients: Hypromellose, Rice hull concentrate, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best Bone Maker with Bonolive (olive leaf extract) is a calcium-free bone health supplement that has been clinically studied to increase osteoblasts, cells that build bones.

Formulation

Easy to swallow in just one small capsule per day Helps increase bone building cells (osteoblasts) Helps decrease bone dissolving cells (osteoclasts) Helps support bone density Water soluble for superior bioavailabillty

Calcium free

Helps support bone density

Non-GMO Gluten free Soy free

Vegan

This product contains natural ingredients that may vary in color.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Science-Based Nutrition

Seals/Symbols

Vegan

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 capsule daily with or without food, or as recommended by a nutritionally-informed physician.

Storage

Store in a cool dry place.

Brand IP Statement(s)

Bonolive is a trademark of BioActor B.V. Bone Maker is a registered trademark of Doctor's Best, Inc.

See for yourself

Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Bonolive

No known
interactions
250 mg per serving Form: Olive (Olea europaea L.) leaf ext., Olive Polyphenols

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Bonolive monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice hull concentrate, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Bone Maker with Bonolive Olive Leaf Extract 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Bone Maker with Bonolive Olive Leaf Extract 250 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
State
California
ZipCode
92612
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best: Common Questions

Does Bone Maker with Bonolive Olive Leaf Extract 250 mg by Doctor's Best interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Bone Maker with Bonolive Olive Leaf Extract 250 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Bone Maker with Bonolive Olive Leaf Extract 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the difference between this supplement and olive oil I cook with?
This is a concentrated extract of olive leaf—not the oil you'd use in cooking. While olives and olive oil as foods are very safe, concentrated supplements like this one have been studied less. That's why we recommend getting the green light from your doctor before you start.
Will this help my bones?
That's the theory, but we don't have reliable evidence yet that Bonolive works for osteoporosis or bone health. The evidence is currently insufficient to rate. Talk with your doctor about proven approaches to bone strength.
What side effects might I see?
Most people tolerate it well. Headache and stomach discomfort were the most common complaints in trials. One person reported skin issues. If you have seasonal allergies to olive pollen, keep that in mind.
Is it safe if I'm pregnant or breastfeeding?
We don't have safety data on file for this ingredient during pregnancy or lactation. Talk with your doctor or pharmacist before taking it—they can weigh what you know about your specific situation.
Does this product have any fillers or extra stuff?
Besides the active olive leaf extract, it contains hypromellose (the capsule), rice hull concentrate, and stearic acid (a binder). No major fillers, but those inactive ingredients are there.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bone Maker with Bonolive Olive Leaf Extract 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bone Maker with Bonolive Olive Leaf Extract 250 mg label
Go deeper

The Full Monographs Behind Bone Maker with Bonolive Olive Leaf Extract 250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Bone Maker with Bonolive Olive Leaf Extract 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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