Bone Strength Formula With KoAct By Life Extension Overview & Drug Interactions
Check For Interactions With Bone Strength Formula With KoAct
Supplement: Bone Strength Formula With KoAct by Life Extension
This product contains
Below is a list of the 'active' ingredients listed on the supplement label for this product.
For a list of 'other ingredients', such as fillers, please see the 'Label Information' section on this page.
Vitamin D3
Vitamin D is a fat-soluble vitamin that plays a crucial role in several bodily processes. It helps the body absorb calcium and phosphorus, which are necessary for healthy bones and teeth. It is also important for immune system function and may help to protect against certain diseases. Vitamin D is found in a variety of foods, including fatty fish, egg yolks, and fortified foods such as milk and cereal. It is also produced by the body when the skin is exposed to sunlight. Vitamin D supplements are available in a variety of forms, including tablets, capsules, and liquids. The recommended daily intake of vitamin D varies depending on age, sex, and other factors, and it is important to follow the dosage recommendations provided by a healthcare professional. There are several different forms of vitamin D available, with the two most popular being ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3).
See More Information Regarding Vitamin DIngredient Group | Vitamin D |
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Category | vitamin |
- Cholecalciferol
Calcium
Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding CalciumIngredient Group | Calcium |
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Category | mineral |
-
KoAct(R) Calcium Collagen Chelate
Description:Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium
Ingredient Group Calcium Category non-nutrient/non-botanical
Calcium Fructoborate
Description:Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion. Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass. Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.
See More Information Regarding Calcium
Ingredient Group Calcium Fructoborate Category non-nutrient/non-botanical
Magnesium
Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement. There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines. Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.
See More Information Regarding MagnesiumIngredient Group | Magnesium |
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Category | mineral |
- Magnesium Citrate
Silicon
Silicon, atomic number 14, is the second most abundant element on Earth, after oxygen. It is present in the human body in small amounts (such as in the skin, hair, and nails) and is considered a trace mineral in that regard. Dietary sources of silicon include oats, barley, rice, and some fruits/vegetables. Silicon is a popular dietary supplement, often consumed in the form of silica, which is a chemical compound made up of silicon and oxygen, or as silicic acid (also known as orthosilicic acid). Another common form of silicon utilized is Choline-stabilized orthosilicic acid (ch-OSA), which is the active ingredient in the popular product Biosil. Silicon is used for its purported effects to improve the health and appearance of the skin, hair, and nails. It has also historically been used for other health conditions, such as osteoporosis, cardiovascular disease, and cognitive decline.
See More Information Regarding SiliconIngredient Group | Silicon |
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Category | mineral |
- Bamboo
dried Plum
Ingredient Group | Plum |
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Category | botanical |
- Polyphenols (50%)
Boron
Boron is a trace mineral that is found in a variety of foods, including fruits, vegetables, nuts, and legumes. It is also available as a dietary supplement. Boron is thought to play a role in bone health, as it may help the body metabolize calcium, magnesium, and phosphorus. Some preliminary research also suggests that boron may have anti-inflammatory effects and may help to improve cognitive function. However, more research is needed to confirm these potential benefits. It is important to note that boron is not an essential nutrient and deficiency is rare. The recommended dietary allowance (RDA) for boron is not established, however, the safe upper limit is 20mg/day. Taking high doses of boron can cause skin irritation, nausea, vomiting, and diarrhea. There are several patented forms of boron available in dietary supplements, such as Albion Bororganic Glycine.
See More Information Regarding BoronIngredient Group | Boron |
---|---|
Category | mineral |
- Calcium Fructoborate
Drugs that interact with Bone Strength Formula With KoAct by Life Extension
Below is a list of drug interactions for each ingredient in this supplement product. Please note that a supplement product may contain more than one ingredient that has interactions.
Label Information
Supplement Facts:
Daily Value (DV) Target Group(s): | Adults and children 4 or more years of age |
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Minimum serving Sizes: |
4 Capsule(s)
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Maximum serving Sizes: |
4 Capsule(s)
|
Servings per container | 30 |
Ingredient | Amount per Serving | Group | % DV, Adults & children 4+ years |
---|---|---|---|
Vitamin D3 |
1000 IU
|
Vitamin D |
|
Calcium |
300 mg
|
Calcium |
|
KoAct(R) Calcium Collagen Chelate |
3000 mg
|
Calcium |
|
Calcium Fructoborate |
0 NP
|
Calcium Fructoborate |
|
Magnesium |
100 mg
|
Magnesium |
|
Silicon |
5 mg
|
Silicon |
|
dried Plum |
100 mg
|
Plum |
|
Boron |
3 mg
|
Boron |
|
Other Ingredients: |
Vegetable Cellulose
Vegetable Stearate
Maltodextrin
Forms
Corn Starch
|
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Label Statments:
General Statements |
- The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging.
- The use of diets high in collagen to improve bone health dates back to ancient cultures.
- This remarkable ingredient allows for greater strength and flexibility, so your bones can absorb energy, reducing the risk of age-related injuries.
- If you have any questions about this, please call a Life Extension Health Advisor who can help to tailor a supplement program that meets your individual bone-care needs at 1-800-226-2370.
- References
1. Hooshmand 5 et al. Evidence for bone reversal properties of a calcium-collagen chelate, a novel dietary supplement. J Food Nutr Disor. 2013;2(1):1-6.
2. Jugdaohsingh R et al. Dietary Silicon Intake is Positively Associated with Bone Mineral Density In Men and Premenopausal Women of the Framingham Offspring Cohort. J Bone Miner Res. 2004;19(2):297-307.
3. Arjmandi BH, Khalil DA, Lucas EA, et al. Dried plums improve indices of bone formatino in postmenopausal women. J Womens Health Gend Based Med. 2002 Jan;11(1):61-8.
4. Bu SY, Lerner M, Stoecker BJ, et al. Dried plum polyphenols inhibit osteoclastogenesis by down-regulating NFATc1 and inflammatory mediators. Calcif Tissue Int. 2008 Jun;82(6):475-88.
5. Franklin M, BuSY, Lerner MR, et al. Dried Plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway. Bone.2006 Dec;39(6):1331-42.
6. Bu Sy, Hunt TS, Smith BJ. Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2, osterix and IGF-I. J Nutr biochem. 2009 Jan;20(1):35-44.
7. Bu Sy, Lucas EA, Franklin M, et al. Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporos Int. 2007 Jul;18(7):931-42.
8. Deyhim F, Stoecker BJ, Brusewitz GH, Devareddy L, Arjimandi BH. Dried plum reverses bone loss in an osteopenic rat model of osteoporosis. Menopause. 2005 Nov;12(67):755-62.
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Precautions |
- You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health program. You should not stop taking any medication without first consulting your physician.
- Warnings
~ Keep out of reach of children
- ~ Do not exceed recommended dose
~ Do not purchase if outer seal is broken or damaged.
- ~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating
|
Brand IP Statement(s) |
- Foundation for Longer Life
- KoAct(R) helps maintain bone strength and mineral density.1
- If you need extra bone support, ask your healthcare professional how Bone Strength Formula with KoAct(R) can be part of a comprehensive nutritional program in conjunction with proper resistance exercise. Life Extension offers several mineral formulas that may complement Bone Strength Formula with KoAct(R) to ensure optimal mineral intake.
- KoAct(R) is a registered trademark of AIDP, Inc.
Fruitex B(R) and OsteoBoron(R) are registered trademarks of VDF Futureceuticals, Inc. U.S. Patent No. 5,962,049.
- All contents Copyright (C) 1995-2013 Life Extension(R) All rights reserved
|
Formula |
- Life Extension brings you this exciting formulation with KoAct(R), a patented chelated form of calcium and collagen designed to maintain optimal bone health.
- Additional plant extracts from bamboo and dried plum have also been added for bone-protective minerals and polyphenols.2-8
- Bone Strength Formula with KoAct(R) contains the following ingredients:
Vitamin D3
~ Facilitates absorption of calcium into the bloodstream.
~ Regulates how much calcium enters and leaves bone tissue.
~ Helps regulate healthy cell division and differentiation.
~ Functions as a vital co-factor in bone mineralization through the absorption of calcium and phosphorus.
Calcium
~ KoAct(R) is a unique patented chelated compound of calcium and hydrolyzed collagen peptides (type I collagen) designed to enhance collagen support and turnover while supporting optimal bone mineral density and strength.
Magnesium
~ A critical component of our skeletin, with 50-60% of totally body magnesium found in bone
~ Positively influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding.
Silicon
~ Plays an important role in bone formation through the synthesis and/or stabilization of collagen.
Dried Plu
~ Supports osteoblas (bone building cells) activity and function by upregulating cell-signaling compounds (Runx2, Osterix and IGF-1) and enhancing expression of an enzyme (lysyl oxidase) that is involved in collagen cross-linking.
Boron
~ Impacts steroid hormone metabolism - affecting the levels of estrogens and testosterone.
- Calcium Collagen Oxide
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Suggested/Recommended/Usage/Directions |
- Dosage and Use ~ Take four capsules daily in divided doses with or without food, or as recommended by a healthcare practitioner.
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FDA Disclaimer Statement |
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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Brand Information
See all products by this brand
To report a serious adverse event or obtain product information, contact | |
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Phone Number | 1-866-280-2852 |
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Parts of this content are provided by the Therapeutic Research Center, LLC and the Dietary Supplement Label Database.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.