No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Bowel Guard Ingredients & Drug Interactions

by Peak Biome

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Bowel Guard is a dietary supplement by Peak Biome with 7 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Bowel Guard by Peak Biome

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Bowel Guard Enzyme Blend” is a proprietary blend — the label gives one combined amount (368 mg) without saying how much of each component you get.

Bowel Guard contains seven active ingredients: a blend of digestive enzymes. Protease, Lactase, Lipase, and Alpha-Amylase are enzymes that help break down protein, milk sugar, fat, and starch respectively.

Peptidase, Invertase, and Cellulase are also present to support the breakdown of different food components. The capsule also holds inactive ingredients — hypromellose, microcrystalline cellulose, magnesium stearate, and silicon dioxide — which are standard binders and flow agents.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).

The data we hold shows Lactase is effective for lactose intolerance — that's the most established claim. For Lipase and other enzymes in the blend, the evidence for conditions like inflammatory bowel disease (IBD) or indigestion (dyspepsia) hasn't been rated as reliable.

We don't hold effectiveness ratings for Protease, Peptidase, Invertase, Cellulase, or Alpha-Amylase in the data available to us.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lactase Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and Lactase are generally well tolerated, though protease may cause digestive upset or allergic reactions in some people. Lipase is generally well tolerated in supplement form.

All three enzymes carry a caution during pregnancy — there isn't enough safety data to be confident, so check with your doctor first. For breastfeeding, the same caution applies: limited data exists, so ask your doctor or pharmacist before using.

Rare allergic reactions to powdered lactase have been reported in occupational settings; airborne exposure to protease has occasionally triggered allergy symptoms in workers.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lactase Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we don't hold interaction data for Peptidase, Invertase, Cellulase, or Alpha-Amylase, so check your exact medications with the search tool on this page before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Bowel Guard is a digestive enzyme blend most useful if you have trouble digesting milk sugar (lactose). If you're pregnant or breastfeeding, talk with your doctor before starting it.

Because we haven't checked all the ingredients against medications, run your prescription list through our medication checker or ask your pharmacist to review it with you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bowel Guard, straight from the product label.

Brand Peak Biome
Barcode (UPC) 860002153704
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 316393
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bowel Guard by Peak Biome, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
860002153704
IngredientAmount% DV
Peptidase0 NP--
Invertase0 NP--
Protease0 NP--
Lactase0 NP--
Cellulase0 NP--
Lipase0 NP--
Alpha-Amylase0 NP--
Bowel Guard Enzyme Blend368 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule with each meal.

General Statements

To reorder, visit www.peakbiome.com/more

Precautions

Usage Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

Keep out of reach of children.

Storage

Store in cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Bowel Guard by Peak Biome label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bowel Guard by Peak Biome

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bowel Guard Enzyme Blend

368 mg per serving

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bowel Guard by Peak Biome Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Bowel Guard. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Bowel Guard, from the product label.

Peak Biome

See all Peak Biome products
Name
Peak Biome Inc.
City
Scranton
State
PA
ZipCode
18504
Phone Number
(877) 977-7774
Web Address
support.peakbiome.com
Pharmacist Counseling Corner

Bowel Guard by Peak Biome: Common Questions

Does Bowel Guard by Peak Biome interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Bowel Guard. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Bowel Guard contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me digest food better?
Bowel Guard contains enzymes meant to help break down fats, proteins, and carbohydrates. Lactase in particular is effective for lactose intolerance. For other digestive issues, the evidence we have isn't strong enough to rate how well it works.
Is it safe if I'm lactose intolerant?
Yes — Lactase, one of the active ingredients, is effective for lactose intolerance. It helps you digest milk sugar. Just check with your doctor if you have any questions about your particular situation.
Can I take this while pregnant?
The safety data for these enzymes during pregnancy is limited. Lactase is likely safe, but Protease and Lipase haven't been well studied. Talk with your doctor before starting it — that's the best way to get personalized advice.
Are there any side effects?
These enzymes are generally well tolerated. Protease may cause digestive upset or allergic reactions in some people. Rare allergic reactions to lactase have been reported in workers exposed to powdered form, but that's uncommon.
What are all the ingredients?
There are seven active enzymes: Protease, Lactase, Lipase, Peptidase, Invertase, Cellulase, and Alpha-Amylase. The capsule also contains hypromellose, microcrystalline cellulose, magnesium stearate, and silicon dioxide, which are inactive binders and fillers.
Is it safe to breastfeed while taking this?
There's limited safety data for these enzymes during breastfeeding. Talk with your doctor or pharmacist first — they can help you decide if it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bowel Guard is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bowel Guard label
Sources

Sources & How We Checked

Bowel Guard's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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