Catechu Sugar Free Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Catechu Sugar Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Catechu Sugar Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for mouth and throat soreness, diarrhea and digestive upset, skin wounds and bleeding gums.Based on those ingredients, 475 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Catechu Herb Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Catechu Sugar Free by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Catechu Sugar Free by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Catechu Sugar Free by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Catechu Sugar Free is a one-ingredient liquid supplement: catechu herb extract, a concentrated form of an astringent plant used in traditional medicine. The liquid also contains alcohol, water, and glycerin as inactive ingredients to deliver the extract.
Does it work?
Couldn't assess
The evidence on catechu for exercise-induced muscle soreness and osteoarthritis is insufficient—we don't have reliable data showing it works for these uses. The facts we hold don't establish that this supplement is effective for any particular condition.
How safe is it?
Well-documented data
Catechu is likely fine for short-term use in food-like amounts, but safety data on concentrated supplements like this one are limited in humans. The facts note that a different combination product containing catechu (Limbrel) was linked to rare reports of serious liver and lung injury, though your single-ingredient supplement is not that product.
Pregnancy is not recommended due to insufficient safety data. Breastfeeding safety is unknown, so it's safer to avoid it.
Meds to double-check
Moderate interaction found
Before you take Catechu Sugar Free, double-check your exact medications against our interaction tool. The main types to flag are blood pressure medications (antihypertensives), theophylline and other CYP1A2-processed drugs, and immunosuppressants—all have moderate interactions documented with catechu.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This supplement may appeal to people looking for joint or muscle support, but the evidence for those uses isn't established. If you take blood pressure medication, theophylline, or any drug that affects your immune system, check with your pharmacist before starting—the interaction potential is real.
Given the limited safety data on concentrated catechu, talk it over with us first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Catechu Sugar Free, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 6175033258774 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 324894 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Catechu Sugar Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Catechu Herb Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Acacia catechu
Organic alcohol
FDA Statement of Identity
Herbal Supplement
General Statements
Organic raw material.
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Catechu Sugar Free by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Catechu Sugar Free by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Catechu Herb Extract, Dry
Interacts with475 drugs
Catechu is an astringent extract made from the heartwood of the Acacia (Senegalia) catechu tree, used traditionally for mouth sores, sore throat, diar...
Catechu Herb Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Catechu Sugar Free by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Catechu Sugar Free by Herbal Terra contains one active ingredient—catechu herb extract—that has documented interactions with 469 individual medications across several drug categories.
The most serious concern involves blood pressure medications (antihypertensives): catechu may lower blood pressure on its own, and combining it with your blood pressure drugs could push your pressure too low.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take theophylline (a breathing medication) or other drugs processed through the CYP1A2 pathway in your liver. Catechu may slow how your body clears these drugs, raising their levels and effects to potentially unsafe amounts.
Additionally, if you take immunosuppressants (drugs that quiet your immune system after transplant or for certain conditions), catechu's immune-boosting effects might interfere with how well they work.
Altogether, these interactions span 469 individual medications. Use the medication checker below to run through your exact prescriptions before you start this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Catechu Sugar Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Catechu Sugar Free interact with 475 drugs. Click any drug to see the details.
1 of the 1 ingredient in Catechu Sugar Free interact with drugs. Each result below shows which ingredient is responsible. Catechu Herb Extract, Dry
Acetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Orphenadrine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Catechu Sugar Free — through 1 ingredient. Tap an ingredient for the detail:
Catechu Herb Extract, DryCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Read the full Catechu Herb Extract, Dry + Acetaminophen, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Catechu Sugar Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Catechu Herb Extract, Dry
Antihypertensive Drugs
Theoretically, concomitant use with antihypertensive drugs might increase the risk of hypotension.
Catechu might lower blood pressure.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, black catechu may increase the levels and clinical effects of CYP1A2 substrates.
Animal research shows that black catechu can increase theophylline concentrations in the blood, possibly by inhibiting CYP1A2. Theophylline is a CYP1A2 substrate.
Immunosuppressants
Theoretically, catechu might interfere with immunosuppressant therapy.
Animal and in vitro studies suggest that catechu has immunomodulating effects.
Theophylline
Theoretically, black catechu may increase the levels and clinical effects of theophylline.
Animal research shows that black catechu can increase theophylline concentrations in the blood, possibly by inhibiting cytochrome P450 1A2.
Brand information
Manufacturer and brand details for Catechu Sugar Free, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Catechu Sugar Free by Herbal Terra: Common Questions
Does Catechu Sugar Free by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
Is it safe to breastfeed while taking this?
Does catechu actually work for sore muscles or joint pain?
What's the alcohol content in this liquid?
Are there any fillers or artificial ingredients?
I heard catechu can damage your liver. Is this product safe?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Catechu Sugar Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Catechu Sugar Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Catechu Sugar Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Catechu 9 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Sham JS, Chiu KW, Pang PK. Hypotensive action of Acacia catechu. Planta Med 1984;50:177-80.
- Chalasani N, Vuppalanchi R, Navarro V, et al. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Ann Intern Med 2012;156:857-60. PubMed
- Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Ann Intern Med 2012;156:894-5. PubMed
- PL-Detail Document, Liver Toxicity and Limbrel. Pharmacist's Letter/Prescriber's Letter. September 2012.
- Al-Mohizea AM, Raish M, Ahad A, et al. Pharmacokinetic interaction of Acacia catechu with CYP1A substrate theophylline in rabbits. J Tradit Chin Med 2015;35(5):588-93. PubMed
- Papafragkakis C, Ona MA, Reddy M, et al. Acute hepatitis after ingestion of a preparation of chinese skullcap and black catechu for joint pain. Case Reports Hepatol 2016;2016:4356749. PubMed
- Sunil MA, Sunitha VS, Ashitha A, et al. Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential. J Food Drug Anal. 2019;27(1):195-207. PubMed
- US Food and Drug Administration (FDA). FDA Alerts Consumers About Potentially Life-Threatening Health Problems Linked to Limbrel. December 19, 2017. Available at: https://www.fda.gov/food/alerts-advisories-safety-information/fda-alerts-consumers-about-pot
Parts of this content are provided by the Therapeutic Research Center, LLC.
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