Major interaction on record — check this product against your medications before combining. Based on 3 of 8 ingredients. Check your meds →
Dietary supplement

Celadrin Complex With Glucosamine Ingredients & Drug Interactions

by Doctor's Best

Celadrin Complex With Glucosamine label
See full label image
Tablet Or Pill Category: Fat/fatty Acid
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Celadrin Complex With Glucosamine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Celadrin Complex With Glucosamine is a dietary supplement by Doctor's Best with 8 active ingredients. Its ingredients are commonly taken for osteoarthritis, joint pain and stiffness, cartilage support.Based on those ingredients, 472 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A Palmitate, Glucosamine Sulfate 2KCl. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Celadrin Complex With Glucosamine by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with Celadrin Complex With Glucosamine by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Celadrin Complex With Glucosamine by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “Celadrin” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 8 ingredients, 3 of which are active. Vitamin A Palmitate is a form of vitamin A, a fat-soluble nutrient your body stores and uses for vision, skin, and immune function.

Glucosamine Sulfate 2KCl is a compound naturally found in joint cartilage; it's used to support cartilage structure and may help with joint comfort. Tapioca is a starch ingredient that serves as a binder or filler.

The other active ingredients—cetyl myristoleate, cetyl myristate, cetyl laurate, cetyl palmitoleate, and cetyl oleate—are fatty substances that make up the Celadrin blend, a proprietary combination meant to support joint and skin health. The tablet also contains inactive ingredients (cellulose, croscarmellose sodium, and silicon dioxide) that help form and stabilize the pill.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports joint function and mobility.
  • We looked for evidence on: Joint pain, Knee pain, Osteoarthritis, Rheumatoid arthritis (RA), cartilage health, joint flexibility — and 1 related terms.
  • The strongest evidence on file: Glucosamine is rated "Likely Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Glucosamine is rated "Insufficient Reliable Evidence To Rate" for Rheumatoid arthritis (RA), Joint pain, Knee pain.
  • Also on file: Vitamin A is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis.

Vitamin A palmitate is effective for vitamin A deficiency and possibly effective for oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia. Glucosamine is likely effective for osteoarthritis but has insufficient evidence for back pain, aging skin, cancer, or metabolic dysfunction-associated fatty liver disease.

For the Celadrin blend itself and tapioca as components of this product, the effectiveness data we hold doesn't establish their benefits for the conditions this product is marketed for. If you're considering this product for a specific reason, talk with your doctor or pharmacist about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Glucosamine Vitamin A Tapioca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A palmitate is generally well tolerated at recommended doses but can build up in your body and become toxic at high doses, causing serious effects like liver damage, headache, and vision problems in rare cases. Chronic high-dose use can cause skin peeling, hair loss, and brittle nails.

Glucosamine is generally well tolerated orally, with the most common side effects being bloating, constipation, cramps, diarrhea, heartburn, and nausea. Rarely, allergic reactions including anaphylaxis have been reported, and asthma exacerbations have been linked to glucosamine-chondroitin products.

Tapioca is considered safe as a food and is well tolerated, though it may cause abdominal pain, bloating, flatulence, or vomiting in some people.

Side effects, ingredient by ingredient Glucosamine Vitamin A Tapioca

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Glucosamine, Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 473 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take warfarin or other blood thinners (Major risk from both vitamin A and glucosamine), retinoid medications like isotretinoin (Major risk from vitamin A), tetracycline antibiotics, chemotherapy drugs like etoposide or doxorubicin, other drugs that can stress the liver, or acetaminophen. No interactions are documented for the cetyl ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product combines vitamin A, glucosamine, and other ingredients meant to support joint and skin health. It's important to check your medications against the interaction list before starting—especially if you take blood thinners, retinoid acne medications, tetracycline antibiotics, or chemotherapy.

If you're pregnant, breastfeeding, or have liver disease, talk with your doctor or pharmacist before taking it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Celadrin Complex With Glucosamine, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950001329
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Aug 24, 2016
DSLD ID 63926
Product type Fat/fatty Acid
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Celadrin Complex With Glucosamine by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
753950001329
IngredientAmount% DV
Vitamin A Palmitate0 NP--
Glucosamine Sulfate 2KCl500 mg--
Tapioca0 NP--
Cetyl Myristoleate0 NP--
Cetyl Myristate0 NP--
Cetyl Laurate0 NP--
Cetyl Palmitoleate0 NP--
Cetyl Oleate0 NP--
Celadrin500 mg--

Other ingredients: Cellulose, Croscarmellose Sodium, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS

Supports joint function and mobility*

SUPPORTS JOINT FUNCTION & MOBILITY*

General

YDRB132

Formula

Celadrin Complex with Glucosamine provides a combination of Celadrin and sodium-free glucosamine sulfate.

Contains Shellfish

Formulation

Celadrin Complex with Glucosamine provides a combination of Celadrin and sodium-free glucosamine sulfate.

Non-GMO and Gluten Free

Brand IP Statement(s)

Celadrin is a proprietary blend of esterified fatty acids that have been shown to benefit joint function and flexibility.*

Science-Based Nutrition

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Contains Shellfish

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 tablet three times daily, with or without food, or as recommended by a nutritionally-informed physician.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Celadrin Complex With Glucosamine by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Celadrin Complex With Glucosamine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Celadrin Complex With Glucosamine by Doctor's Best

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glucosamine Sulfate 2KCl

Interacts with
170 drugs
500 mg per serving

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...

Glucosamine Sulfate 2KCl monograph & interactions

Celadrin

500 mg per serving
  • › Vitamin A Palmitate
  • › Tapioca
  • › Cetyl Myristoleate
  • › Cetyl Myristate
  • › Cetyl Laurate
  • › Cetyl Palmitoleate
  • › Cetyl Oleate

Other (inactive) ingredients: Cellulose, Croscarmellose Sodium, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Celadrin Complex With Glucosamine by Doctor's Best Drug Interactions

Want to check YOUR meds against Celadrin Complex With Glucosamine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
472Drugs
11 Major 388 Moderate 73 Minor

Ingredients driving the most interactions

Vitamin A Palmitate 387
Glucosamine Sulfate 2KCl 170

Individual Drug Interactions

The ingredients in Celadrin Complex With Glucosamine interact with 472 drugs. Click any drug to see the details.

2 of the 8 ingredients in Celadrin Complex With Glucosamine interact with drugs. Each result below shows which ingredient is responsible. Vitamin A Palmitate Glucosamine Sulfate 2KCl

Each ingredient & the kinds of drugs it affects

For each ingredient in Celadrin Complex With Glucosamine with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A Palmitate4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A Palmitate full monograph & interactions

Glucosamine Sulfate 2KCl4 drug types · 170 drugs

Warfarin (Coumadin)

Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.

Likelihood Probable Evidence D
Topoisomerase Ii Inhibitors

Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.

Likelihood Possible Evidence B
Antidiabetes Drugs

Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.

Likelihood Unlikely Evidence B
Glucosamine Sulfate 2KCl full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Celadrin Complex With Glucosamine, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
San Clemente
State
CA
ZipCode
92673
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Celadrin Complex With Glucosamine by Doctor's Best: Common Questions

Does Celadrin Complex With Glucosamine by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Celadrin Complex With Glucosamine has a known interaction with 472 medications, including 11 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Celadrin Complex With Glucosamine contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe if I take warfarin?
No—both vitamin A and glucosamine in this product can increase your bleeding risk and have been linked to higher INR levels in patients on warfarin. Talk with your doctor before taking it; they may need to monitor you more closely or adjust your dose.
Can I take this if I'm on isotretinoin for acne?
No. The vitamin A in this product is a derivative of the same compound in isotretinoin, and combining them can cause dangerously high vitamin A levels in your body. Check with your doctor or pharmacist before taking any vitamin A supplement while on isotretinoin.
What are the most common side effects of glucosamine in this product?
Bloating, constipation, cramps, diarrhea, heartburn, and nausea are the most commonly reported side effects of oral glucosamine. Most people tolerate it well, but if your stomach is sensitive, these effects may bother you.
Will this help my osteoarthritis?
Glucosamine is likely effective for osteoarthritis, so that ingredient has research backing. The other active ingredients in the product (the Celadrin blend) don't have established effectiveness data in what we hold, so talk with your doctor about whether this product is right for your situation.
Is it safe in pregnancy?
Vitamin A in normal recommended amounts is okay in pregnancy, but high doses can cause birth defects—and glucosamine doesn't have enough safety information. Because this product contains both, talk with your doctor or pharmacist before taking it while pregnant.
Why are there 473 medication interactions if I only see a few drug types listed?
That number counts every individual medication within each drug type that could interact—so 'warfarin' alone is one drug, but 'hepatotoxic drugs' includes hundreds of medications that can stress the liver. The ingredient data we hold documents interactions with major drug categories, not every single pill that falls into them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Celadrin Complex With Glucosamine is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Celadrin Complex With Glucosamine label
Go deeper

The Full Monographs Behind Celadrin Complex With Glucosamine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucosamine

Interacts with 170 drugs

Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...

Read the full Glucosamine monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Tapioca

Tapioca is a starch made from the root of the cassava plant and is mainly used as a food ingredient and gluten-free thickener, not as a medicinal supplement. It is generally safe to eat in n...

Read the full Tapioca monograph →
Sources

Sources & How We Checked

Celadrin Complex With Glucosamine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 93 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Glucosamine 58 references
  1. Adams ME. Hype about glucosamine. Lancet 1999;354:353-4. PubMed
  2. Balkan B, Dunning BE. Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats. Diabetes 1994;43:1173-9. PubMed
  3. Giaccari A, Morviducci L, Zorretta D, et al. In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia. Diabetologia 1995;38:518-24. PubMed
  4. Holmang A, Nilsson C, Niklasson M, et al. Induction of insulin resistance by glucosamine reduces blood flow but not interstitial levels of either glucose or insulin. Diabetes 1999;48:106-11. PubMed
  5. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol 1999;26:2423-30.
  6. Barclay TS, Tsourounis C, McCart GM. Glucosamine. Ann Pharmacother 1998;32:574-9.
  7. Shankar RR, Zhu JS, Baron AD. Glucosamine infusion in rats mimics the beta-cell dysfunction of non-insulin-dependent diabetes mellitus. Metabolism 1998;47:573-7.
  8. Almada A, Harvey P, Platt K. Effects of chronic oral glucosamine sulfate on fasting insulin resistance index (FIRI) in non-diabetic individuals. FASEB J 2000;14:A750.
  9. Reginster JY, Deroisy R, Rovati LC, et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomised, placebo-controlled trial. Lancet 2001;357:251-6.
  10. Does glucosamine increase serum lipid levels and blood pressure? Pharmacist's Letter/Prescriber's Letter 2001;17(11):171115.
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Tapioca 4 references
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  3. Astina J, Sapwarobol S. Attenuation of glycaemic and insulin responses following tapioca resistant maltodextrin consumption in healthy subjects: a randomised cross-over controlled trial. J Nutr Sci 2020;9:e29. PubMed
  4. Astina J, Saphyakhajorn W, Borompichaichartkul C, Sapwarobol S. Tapioca resistant maltodextrin as a carbohydrate source of oral nutrition supplement (ONS) on metabolic indicators: a clinical trial. Nutrients 2022;14(5):916. PubMed

See these in context on the Tapioca monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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