No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Chestnut Leaf Ingredients & Drug Interactions

by Pure Herbs

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Chestnut Leaf is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for cough and whooping cough, respiratory ailments, sore throat (topical/gargle).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Chestnut Leaf by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: American Chestnut Leaf Extract. It's used traditionally for cough and sore throat (pharyngitis), though the evidence for either use isn't well established in the data we hold.

The extract is made from the leaves of the American chestnut tree.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see American Chestnut's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: maintain healthy respiratory system.
  • We looked for evidence on: Cough, Pharyngitis, Respiratory tract inflammation, Bronchitis.
  • The closest evidence on file: American Chestnut is rated "Insufficient Reliable Evidence To Rate" for Cough (Natural Medicines).
  • Also on file: American Chestnut is rated "Insufficient Reliable Evidence To Rate" for Pharyngitis.

The evidence for American Chestnut Leaf Extract isn't established in our data. For both cough and sore throat, we have insufficient reliable evidence to rate whether it works.

That doesn't mean it doesn't — it means the research supporting it isn't solid enough for us to say one way or the other.

The evidence, ingredient by ingredient American Chestnut

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chestnut leaf contains high levels of tannins, compounds that can irritate your stomach or interfere with how your body absorbs nutrients, so take caution. Little modern safety data exists for this product overall.

Because there isn't enough safety information, it should be avoided during pregnancy and while breastfeeding — talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing and want to know about your options.

Side effects, ingredient by ingredient American Chestnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for American Chestnut Leaf Extract. Still, run your medications through the checker on this page before starting, or ask your pharmacist to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

Chestnut Leaf might interest someone looking for a traditional remedy for cough or sore throat, but the evidence for it isn't clear. The tannin content means stomach irritation is possible, so be aware of that.

Pregnancy and breastfeeding are cautions here. Check with your doctor or pharmacist before starting it, especially if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chestnut Leaf, straight from the product label.

Brand Pure Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278762
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chestnut Leaf by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
IngredientAmount% DV
American Chestnut Leaf Extract1897 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Helps maintain a healthy respiratory system.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

See for yourself

Chestnut Leaf by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Chestnut Leaf by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

American Chestnut Leaf Extract

No known
interactions
1897 mg per serving

American chestnut leaves and bark have a long history of folk use for coughs and respiratory complaints, mainly because of their tannin content, which...

American Chestnut Leaf Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chestnut Leaf by Pure Herbs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Chestnut Leaf. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Chestnut Leaf, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Chestnut Leaf by Pure Herbs: Common Questions

Does Chestnut Leaf by Pure Herbs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Chestnut Leaf. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Chestnut Leaf contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is American Chestnut Leaf Extract used for?
It's traditionally used for cough and sore throat (pharyngitis). The evidence for either use isn't well established in our data, so we can't say how well it actually works.
Can I take this while pregnant?
No — there isn't enough safety information, so it's best avoided during pregnancy. Talk with your doctor or pharmacist about what might be safer for you.
Can I take this while breastfeeding?
No — safety while breastfeeding is unknown, so it's best avoided. Ask your doctor or pharmacist about alternatives that are safer while nursing.
What are the side effects?
The product is high in tannins, which can irritate your stomach or affect how your body absorbs nutrients. Little modern safety data exists, so other effects aren't well documented.
Does this interact with my medications?
No interactions are documented in our data for American Chestnut Leaf Extract. To be sure your specific medications are clear, use the interaction checker on this page or ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chestnut Leaf is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chestnut Leaf label
Go deeper

The Full Monographs Behind Chestnut Leaf’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Chestnut Leaf's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

American Chestnut 2 references
  1. Tannins — MedlinePlus Source
  2. Herbs at a Glance — NIH NCCIH Source

See these in context on the American Chestnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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