Chinese Ginseng Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Chinese Ginseng against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chinese Ginseng is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for boosting energy and fighting fatigue, improving mental focus and memory, coping with stress (adaptogen).Based on those ingredients, 1,130 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are CHINESE GINSENG. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Chinese Ginseng by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Chinese Ginseng by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Chinese Ginseng by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Herb Pharm's Chinese Ginseng is a one-ingredient liquid supplement containing Panax ginseng extract. The inactive ingredients are certified organic grain alcohol (the liquid carrier) and ginseng extractives.
Does it work?
Moderate evidence
Chinese Ginseng has evidence for several uses. It's rated possibly effective for erectile dysfunction, sexual arousal, influenza, and cognitive function.
It's also rated possibly effective for multiple sclerosis-related fatigue. These ratings mean the evidence is encouraging but not conclusive—more research would strengthen the case.
How safe is it?
Well-documented data
Panax ginseng is generally well tolerated when taken for up to six months. The most common side effect is insomnia; headache, dizziness, and euphoria have also been reported.
Rare serious effects include anaphylaxis (severe allergic reaction), abnormal heart rhythm, and Stevens-Johnson syndrome (a severe skin reaction). There's some long-term safety concern due to potential hormone-like effects with extended use.
Amenorrhea (loss of menstrual period) has been reported. The safety data advises against use during pregnancy and while breastfeeding—there isn't enough evidence to know whether ginseng is safe at those times.
Talk with your doctor or pharmacist before taking it if you're pregnant, planning pregnancy, or nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check any sedatives you use (especially midazolam), MAOIs or other older antidepressants, blood thinners like warfarin, insulin, HIV medications like raltegravir, Parkinson's medications like selegiline, water pills like furosemide, or any drugs metabolized by the liver enzyme CYP2D6. All carry Moderate-severity interactions with ginseng.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Chinese Ginseng may help with sexual function, mental clarity, or fatigue, but it comes with real medication interactions—especially if you take sedatives, antidepressants, blood thinners, insulin, or heart drugs. Check your prescriptions with our tool before you start.
If you take any regular medications, talk to your pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chinese Ginseng, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Net contents | 8 fl. Oz. |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2013 |
| DSLD ID | 23318 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chinese Ginseng by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| CHINESE GINSENG | 0 NP | -- |
Other ingredients: certified organic grain alcohol, Ginseng extractives
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake Well Before Dispensing From This Bottle
SUGGESTED USE Shake Well Before Using Two to three times per day take 30 to 60 drops in a little water.
FDA Disclaimer Statement
*THIS STATEMENT HAS NOT BEEN EVALUATED BY THE FDA. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.
General Statements
Enhances Physical & Mental Energy & Stamina*
We prepare our Chinese Ginseng Glycerite from whole roots of Panax ginseng plants which are grown, harvested & processed according to traditional Chinese methods and are never fumigated or irradiated.
Our special vacuum concentration process creates a more concentrated extract which is richer in Ginseng's ginsenosides & other bioactive compounds.
214921-9R44
LIQUID HERBAL EXTRACT
FDA Statement of Identity
HERBAL DIETARY SUPPLEMENT
Precautions
Keep Out of the Reach of Children
General
004
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chinese Ginseng by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chinese Ginseng by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size30 Drop(s) Dosage formLiquid Amounts shown are per serving.
CHINESE GINSENG
Interacts with1,130 drugs
Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is mixed and m...
CHINESE GINSENG monograph & interactionsOther (inactive) ingredients: Certified organic grain alcohol, Ginseng extractives. These complete the product’s ingredient list but are not active constituents.
Chinese Ginseng by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Herb Pharm's Chinese Ginseng contains a single active ingredient—Panax ginseng—that interacts with a range of medications.
The most serious documented concern is with midazolam (Versed), a sedative used during medical procedures: research shows ginseng can reduce how much midazolam reaches your bloodstream by nearly half, which may weaken its effect.
Read the full breakdown — every affected drug type, severity by severity
Ginseng also affects several other drug types. It may speed up how your body clears drugs metabolized by the liver enzyme CYP2D6 (a category that includes some depression and heart medications), though the evidence is mixed.
It could reduce the effectiveness of furosemide (Lasix), a water pill, and interfere with monoamine oxidase inhibitors (MAOIs)—older antidepressants—potentially causing insomnia, headache, tremors, or mood swings. Selegiline (Eldepryl), used for Parkinson's disease, may be affected unpredictably.
Ginseng may also lower blood sugar, raising the risk of low blood sugar (hypoglycemia) if you take insulin, and it might increase levels of the HIV medication raltegravir (Isentress), which could stress your liver.
One blood thinner—warfarin (Coumadin)—has a single case report of reduced effectiveness, though it's unclear ginseng was truly the cause. Altogether, these interactions span 1,115 individual medications.
Please check your exact prescriptions with the tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Chinese Ginseng?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Chinese Ginseng interact with 1,130 drugs. Click any drug to see the details.
1 of the 1 ingredient in Chinese Ginseng interact with drugs. Each result below shows which ingredient is responsible. CHINESE GINSENG
Acetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 3a4 (cyp3a4) Substrates, Stimulant Drugs Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 3a4 (cyp3a4) Substrates, Stimulant Drugs Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 3a4 (cyp3a4) Substrates, Stimulant Drugs Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Chinese Ginseng + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Chinese Ginseng + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Chinese Ginseng + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Chinese Ginseng + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6.
Read the full Chinese Ginseng + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Chinese Ginseng — through 1 ingredient. Tap an ingredient for the detail:
Chinese GinsengStimulant Drugs Moderate
Interaction Summary
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Read the full Chinese Ginseng + Acetaminophen, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Chinese Ginseng with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
CHINESE GINSENG
Anticoagulant/Antiplatelet Drugs
Although Panax ginseng has shown antiplatelet effects in the laboratory, it is unlikely to increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro evidence suggests that ginsenoside constituents in Panax ginseng might decrease platelet aggregation. However, research in humans suggests that ginseng does not affect platelet aggregation. Animal research indicates low oral bioavailability of Rb1 and rapid elimination of Rg1, which might explain the discrepancy between in vitro and human research. Until more is known, use with caution in patients concurrently taking anticoagulant or antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking Panax ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research suggests that Panax ginseng might decrease blood glucose levels. Monitor blood glucose levels closely.
Caffeine
Theoretically, taking Panax ginseng with caffeine might increase the risk of adverse stimulant effects.
Panax ginseng has been shown to have stimulant effects. Theoretically, caffeine might have an additive effect on the stimulant effects of Panax ginseng.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Panax ginseng might increase levels of drugs metabolized by CYP2D6. However, research is conflicting.
There is some evidence that Panax ginseng can inhibit the CYP2D6 enzyme by approximately 6%. In addition, in animal research, Panax ginseng inhibits the metabolism of dextromethorphan, a drug metabolized by CYP2D6, by a small amount. However, contradictory research suggests Panax ginseng might not inhibit CYP2D6. Until more is known, use Panax ginseng cautiously in patients taking drugs metabolized by these enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Panax ginseng might increase or decrease levels of drugs metabolized by CYP3A4.
Panax ginseng may affect the clearance of drugs metabolized by CYP3A4. One such drug is imatinib. Inhibition of CYP3A4 was believed to be responsible for a case of imatinib-induced hepatotoxicity. In contrast, Panax ginseng has been shown to increase the clearance of midazolam, another drug metabolized by CYP3A4. Clinical research shows that Panax ginseng can reduce midazolam area under the curve by 44%, maximum plasma concentration by 26%, and time to reach maximum plasma concentration by 29%. Midazolam metabolism was also increased in animals given Panax ginseng. Until more is known, use Panax ginseng cautiously in combination with CYP3A4 substrates.
Estrogens
Theoretically, concomitant use of large amounts of Panax ginseng might interfere with hormone replacement therapy.
Laboratory research and some case reports suggest that Panax ginseng can have estrogenic effects due to competition for estrogen receptors. The estrogenic activity is attributed to the ginsenoside constituents of Panax ginseng.
Furosemide (Lasix)
Theoretically, Panax ginseng might reduce the effects of furosemide.
There is some concern that Panax ginseng might contribute to furosemide resistance. There is one case of resistance to furosemide diuresis in a patient taking a germanium-containing ginseng product.
Imatinib (Gleevec)
Theoretically, Panax ginseng might increase the effects and adverse effects of imatinib.
A case of imatinib-induced hepatotoxicity has been reported for a 26-year-old male with chronic myelogenous leukemia stabilized on imatinib for 7 years. The patient took imatinib 400 mg along with a Panax ginseng-containing energy drink daily for 3 months. Since imatinib-associated hepatotoxicity typically occurs within 2 years of initiating therapy, it is believed that Panax ginseng affected imatinib toxicity though inhibition of cytochrome P450 3A4. CYP3A4 is the primary enzyme involved in imatinib metabolism.
Immunosuppressants
Theoretically, Panax ginseng use might interfere with immunosuppressive therapy.
Panax ginseng might have immune system stimulating properties.
Insulin
Theoretically, taking Panax ginseng with insulin might increase the risk of hypoglycemia.
Clinical research suggests that Panax ginseng might decrease blood glucose levels. Insulin dose adjustments might be necessary in patients taking Panax ginseng; use with caution.
Midazolam (Versed)
Theoretically, Panax ginseng may increase the clearance of midazolam.
Midazolam is metabolized by cytochrome P450 3A4 (CYP3A4). Clinical research suggests that Panax ginseng can reduce midazolam area under the curve by 44%, maximum plasma concentration by 26%, and time to reach maximum plasma concentration by 29%. Midazolam metabolism was also increased in animals given Panax ginseng.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, Panax ginseng can interfere with MAOI therapy.
Concomitant use of Panax ginseng with phenelzine (Nardil) is associated with insomnia, headache, tremors, and hypomania.
Nifedipine (Procardia)
Theoretically, taking Panax ginseng with nifedipine might increase serum levels of nifedipine and the risk of hypotension.
Preliminary clinical research shows that concomitant use can increase serum levels of nifedipine in healthy volunteers. This might cause the blood pressure lowering effects of nifedipine to be increased when taken concomitantly with Panax ginseng.
Qt Interval-Prolonging Drugs
Theoretically, Panax ginseng has an additive effect with drugs that prolong the QT interval and potentially increase the risk of ventricular arrhythmias. However, research is conflicting.
Clinical research shows that short-term use of Panax ginseng can increase the QT interval. However, no changes in QT interval have been identified with prolonged use.
Raltegravir (Isentress)
Theoretically, taking Panax ginseng with raltegravir might increase the risk of liver toxicity.
A case report suggests that concomitant use of Panax ginseng with raltegravir can increase serum levels of raltegravir, resulting in elevated liver enzymes levels.
Selegiline (Eldepryl)
Theoretically, Panax ginseng might increase or decrease levels of selegiline, possibly altering the effects and side effects of selegiline.
Animal research shows that taking selegiline with a low dose of Panax ginseng extract (1 gram/kg) reduces selegiline bioavailability, while taking a high dose of Panax ginseng extract (3 grams/kg) increases selegiline bioavailability. More research is needed to confirm these effects.
Stimulant Drugs
Theoretically, taking Panax ginseng with stimulant drugs might increase the risk of adverse stimulant effects.
Panax ginseng has been shown to have stimulant effects.
Warfarin (Coumadin)
Panax ginseng might affect the clearance of warfarin. However, this interaction appears to be unlikely.
There has been a single case report of decreased effectiveness of warfarin in a patient who also took Panax ginseng. However, it is questionable whether Panax ginseng was the cause of this decrease in warfarin effectiveness. Some research in humans and animals suggests that Panax ginseng does not affect the pharmacokinetics of warfarin. However, other research in humans suggests that Panax ginseng might modestly increase the clearance of the S-warfarin isomer. More evidence is needed to determine whether Panax ginseng causes a significant interaction with warfarin.
Fexofenadine (Allegra)
Theoretically, Panax ginseng might decrease blood levels of oral or intravenous fexofenadine.
Animal research suggests that taking Panax ginseng in combination with oral or intravenous fexofenadine may reduce the bioavailability of fexofenadine. Some scientists have attributed this effect to the ability of Panax ginseng to increase the expression of P-glycoprotein.
Lopinavir/Ritonavir (Kaletra)
Although Panax ginseng has demonstrated variable effects on cytochrome P450 3A4 (CYP3A4), which metabolizes lopinavir, Panax ginseng is unlikely to alter levels of lopinavir/ritonavir.
Lopinavir is metabolized by CYP3A4 and is administered with the CYP3A4 inhibitor ritonavir to increase its plasma concentrations. Panax ginseng has shown variable effects on CYP3A4 activity in humans. However, taking Panax ginseng (Vitamer Laboratories) 500 mg twice daily for 14 days did not alter the pharmacokinetics of lopinavir/ritonavir in 12 healthy volunteers.
Brand information
Manufacturer and brand details for Chinese Ginseng, from the product label.
Chinese Ginseng by Herb Pharm: Common Questions
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The Full Monographs Behind Chinese Ginseng’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Chinese Ginseng's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 66 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Panax Ginseng 66 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC