Cholesterol Balance Ingredients & Drug Interactions
by Natrol
What is this page for?
First and foremost: checking Cholesterol Balance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cholesterol Balance is a dietary supplement by Natrol with 4 active ingredients. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cholesterol Balance by Natrol
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Cholesterol Balance contains four active ingredients, all plant-derived sterols and compounds that help lower cholesterol. Beta-sitosterol is the main one — it's a plant sterol that works on cholesterol in your gut.
The product also includes Campesterol and Stigmasterol (both plant sterols in the same family), plus Phytosterols (a blend that contains the other sterols listed separately) and Citrus Pectin Cellulose Complex, which adds fiber. The tablet also has several inactive ingredients — cellulose, stearic acid, silica, and a few others — that are the binders and fillers that hold the tablet together.
Does it work?
Moderate evidence
Beta-sitosterol, the main ingredient, is likely effective for benign prostatic hyperplasia (an enlarged prostate that causes trouble urinating). For lowering cholesterol in familial hypercholesterolemia (a genetic cholesterol condition) and reducing coronary heart disease risk, the evidence says it's possibly effective — meaning it probably helps, but the data isn't as strong.
We don't have effectiveness ratings on file for Campesterol, Stigmasterol, or Citrus Pectin Cellulose Complex, so we can't speak to what those do in this product.
How safe is it?
Well-documented data
Beta-sitosterol is generally well tolerated when taken short-term. The most common side effects are constipation, diarrhea, gas, indigestion, and nausea.
Some people report reduced appetite. There's also one case report of acute pancreatitis in someone taking beta-sitosterol, though symptoms stopped when he quit — that's very rare.
Beta-sitosterol isn't recommended during pregnancy or while breastfeeding because there isn't enough safety data. We don't have pregnancy or breastfeeding information for the other ingredients, so talk with your doctor or pharmacist if you're pregnant, planning to be, or nursing and want to use this product.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check in this product. We don't hold data on Campesterol, Stigmasterol, or Citrus Pectin Cellulose Complex, so if you take any medications and want a complete picture, ask your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Cholesterol Balance is a reasonable pick if you're looking to support cholesterol levels naturally, especially if you have familial hypercholesterolemia or want to lower your heart disease risk. It's generally well tolerated, though digestive side effects like gas and loose stools can happen.
If you're pregnant or breastfeeding, skip it and check with your doctor first. Run your medications through our checker, and if anything's unclear, your pharmacist is your best resource.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cholesterol Balance, straight from the product label.
| Brand | Natrol |
|---|---|
| Barcode (UPC) | 047469009267 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Dec 22, 2017 |
| DSLD ID | 77578 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cholesterol Balance by Natrol, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Beta Sitosterol | 240 mg | -- |
| Campesterol | 120 mg | -- |
| Stigmasterol | 80 mg | -- |
| Phytosterols | 600 mg | -- |
| Citrus Pectin Cellulose Complex | 60 mg | -- |
Other ingredients: Cellulose, Stearic Acid, Silica, Cellulose Gum, Magnesium Stearate, Methylcellulose, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Beta Sitosterol, also known as Phytosterols, has shown efficacy in maintaining cholesterol levels that are already within a normal range when combined with a healthy calorie reduction and exercise program.
Helps maintain healthy cholesterol levels that are already in the normal range
Precautions
Consult your healthcare professional prior to use if you have or suspect a medical condition, or are taking prescription drugs.
People with allergies to soy should contact their healthcare professional before taking this product.
Do not use if you are pregnant or lactating.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
ITEM: 926 F: 3000307 L: 2004434-9176
Formula
Beta Sitosterol
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 2 tablets, three times daily, preferably with a meal.
Formulation
No yeast, wheat, milk, egg, glutens, artificial colors or flavors, added sugar, starch or preservatives
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cholesterol Balance by Natrol label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cholesterol Balance by Natrol
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Phytosterols
- › Beta Sitosterol
- › Campesterol
- › Stigmasterol
Citrus Pectin Cellulose Complex
Other (inactive) ingredients: Cellulose, Stearic Acid, Silica, Cellulose Gum, Magnesium Stearate, Methylcellulose, Glycerin. These complete the product’s ingredient list but are not active constituents.
Cholesterol Balance by Natrol Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cholesterol Balance. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cholesterol Balance, from the product label.
Natrol
See all Natrol products- Name
- Natrol, Inc.
- City
- Chatsworth
- State
- CA
- ZipCode
- 91311
- Phone Number
- 1-800-262-8765
- Web Address
- www.natrol.com
Cholesterol Balance by Natrol: Common Questions
Does Cholesterol Balance by Natrol interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does beta-sitosterol do?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
What side effects might I get?
Is this the same as saw palmetto?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cholesterol Balance is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cholesterol Balance’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cholesterol Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-sitosterol 7 references
- Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
- Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
- Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
- Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
- Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC