Cholestinol By PurMEDICA Overview & Drug Interactions

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control. There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

Policosanol is a supplement made from the wax of sugar cane or other sources (e.g., beeswax, rice, or wheat germ oil). It is a mixture of 24-34 carbon alcohols comprised primarily of octacosanol (28-C) but also includes tetracosanol (24-C), hexacosanol (26-C), heptacosanol (27-C), triacontanol (30-C), nonacosanol (29-C), triacosanol (30-C), dotriacontanol (32-C), docosanol, (22-C), and tetratriacontanol. It is sometimes marketed as a natural alternative to statin drugs for the treatment of high cholesterol.

Tocotrienols are a type of vitamin E, a fat-soluble vitamin found in a variety of foods. They are structurally similar to tocopherols, the more commonly known form of vitamin E, but have a different molecular structure. Tocotrienols are found in smaller amounts in certain plant-based foods, such as palm oil, rice bran oil, and barley. Unlike tocopherols, tocotrienols are known for their potent antioxidant properties and have been studied for their potential health benefits, including reduced risk of heart disease, stroke, and certain types of cancer. Additionally, tocotrienols have been studied for their ability to regulate cholesterol levels and protect the brain from oxidative damage. Drug interactions with tocotrienols are unlikely, but should be used cautiously if you are taking anticoagulants.

Guggal, also known as Commiphora mukul or Indian bdellium, is a species of tree native to India, Pakistan, and parts of the Middle East. It is known for producing a gum resin that has a long history of use in traditional Ayurvedic medicine. Guggul is used for a variety of purposes, including for the treatment of joint pain, obesity, and high cholesterol. Many guggal preparations are often standardized to contain 2.5% to 5% guggulsterone.

Phosphatidylcholine (PC) is a type of phospholipid that plays a critical role in maintaining the structural integrity and fluidity of cell membranes. Phosphatidylcholine is also a source of choline, which is an essential nutrient that is important for liver function, brain development, and nerve function. Choline is a precursor to acetylcholine, a neurotransmitter that plays a role in memory, mood, and muscle control. Phosphatidylcholine is found naturally in foods, particularly in egg yolks, soybeans, and organ meats such as liver. It is also available as a dietary supplement in the form of capsules, tablets, and liquids. Phosphatidylcholine supplements are sometimes marketed as nootropics, which are substances that are purported to enhance cognitive function and memory.

Garlic (Allium sativum) is a popular culinary herb native to central Asia, but is now widely cultivated. It is a member of the onion family and is known for its pungent smell and flavor. In addition to its culinary use, it has been used medicinally to treat a variety of conditions, including high blood pressure, high cholesterol, and infections.

Grapes are widely grown and cultivated for a variety of uses such as for food and beverage making (e.g., wine). They also have a long history of use in traditional medicine. The fruit and skin of grapes contain various compounds that are believed to have health benefits, including antioxidants such as resveratrol and flavonoids. These compounds may help to protect cells from damage and are purported to reduce the risk of certain chronic diseases. Grapes and grape products may also have anti-inflammatory properties, which may help to reduce inflammation in the body and potentially improve symptoms of certain conditions. Grape seed extracts are also commonly used as a dietary supplement and are often standardized according to the content of polyphenols or proanthocyanidins.

Artichoke (Cynara scolymus) is a perennial plant native to the Mediterranean region that is known for its edible flower buds. Artichokes are a good source of fiber, vitamin C, and other nutrients. Artichoke has a history of use in traditional medicine, and studies show it may have a mild cholesterol-lowering effect and has also been used for gastrointestinal problems, such as heartburn and constipation. Although several parts of the artichoke have been used medicinally, for its use in dietary supplements, a standardized leaf extract is often used.

Inositol is a type of carbohydrate (sugar alcohol) that is found in a variety of foods, including fruits, nuts, and grains. It is also known as vitamin B8 but is not considered 'essential' as it can be synthesized in the human body. Inositol is involved in a number of important physiological processes, including the metabolism of fats, the regulation of insulin, and the transmission of nerve impulses. Inositol is a popular dietary supplement and is believed to have a number of potential health benefits. It is thought to have a role in the treatment of certain mental health conditions, is believed to have a positive effect on cholesterol levels and may be helpful in the prevention or management of heart disease. In addition, inositol may have anti-inflammatory effects and may be helpful in the treatment of certain skin conditions.