Cholesto-Rite Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cholesto-Rite against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cholesto-Rite is a dietary supplement by Native Remedies with 3 active ingredients. Its ingredients are commonly taken for high cholesterol, heart health, metabolic syndrome.Based on those ingredients, 1,136 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rooibos, Guggul Gum, Red Yeast Rice. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cholesto-Rite by Native Remedies
Ask about any prescription or over-the-counter medication and we check it for interactions with Cholesto-Rite by Native Remedies — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cholesto-Rite by Native Remedies
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Cholesto-Rite contains three active ingredients. Red yeast rice is a fermented rice product that contains lovastatin, a statin-type compound used to manage cholesterol.
Rooibos is a South African herb sometimes used in tea. Guggul Gum is a plant resin traditionally used in Ayurvedic medicine.
The product also contains cellulose as an inactive ingredient (a filler).
Does it work?
Moderate evidence
Red yeast rice is rated possibly effective for HIV/AIDS-related dyslipidemia (abnormal cholesterol in people with HIV) and possibly effective for reducing heart attack risk. Rooibos has not been established as effective for the conditions our data covers—age-related cognitive decline, hay fever, anxiety, cancer, heart disease, and diabetes all have insufficient reliable evidence.
Guggul Gum is rated possibly ineffective for obesity and has insufficient evidence for acne, hemorrhoids, and high cholesterol.
How safe is it?
Well-documented data
Red yeast rice works like a statin drug and carries similar risks; product quality varies widely from batch to batch. It is unsafe during pregnancy because of its statin-like effects.
The most common side effects are abdominal discomfort, diarrhea, dizziness, flatulence, headache, heartburn, and nausea. Rare but serious side effects include liver damage and rhabdomyolysis (muscle breakdown).
Rooibos is generally well tolerated in normal beverage amounts, though large long-term doses might cause liver damage in some people. Guggul Gum is generally well tolerated but commonly causes belching, bloating, diarrhea, headache, nausea, and unpleasant taste.
It can also trigger allergic skin reactions or rashes; the risk and severity increase with higher doses. Guggul is unsafe during pregnancy (it may stimulate the uterus) and should be avoided while breastfeeding due to lack of safety data.
There is insufficient pregnancy and breastfeeding data for rooibos; discuss with your doctor or pharmacist before using during pregnancy or while nursing.
Meds to double-check
Moderate interaction found
Before taking Cholesto-Rite, double-check if you're on cyclosporine, other statins, CYP3A4 inhibitors, gemfibrozil, high-dose niacin, or hepatotoxic drugs—these carry moderate-severity risks with red yeast rice. Also verify any CYP2C19, CYP1A2, CYP2D6, CYP2C9, or CYP3A4 substrates; ACE inhibitors; atorvastatin; propranolol; diltiazem; contraceptives; estrogens; blood thinners; thyroid hormone; or tamoxifen, as rooibos and guggul may alter their effectiveness or safety.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is a multi-ingredient supplement with documented interactions across many medication categories—most critically with heart drugs, blood thinners, contraceptives, and statins. If you take any prescription medication, especially for heart disease, blood pressure, blood clotting, or cholesterol, check your exact drugs with the tool on this page before starting.
Talk to your pharmacist or doctor about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cholesto-Rite, straight from the product label.
| Brand | Native Remedies |
|---|---|
| Barcode (UPC) | 810845010450 |
| Net contents | 60 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 21, 2025 |
| DSLD ID | 331764 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cholesto-Rite by Native Remedies, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Red Yeast Rice | 0 NP | -- |
| Proprietary Formula | 800 mg | -- |
| Rooibos | 0 NP | -- |
| Guggul Gum | 0 NP | -- |
Other ingredients: Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Tamper resistant for your protection. Use only if safety seal is intact.
Caution: Safety during pregnancy or breastfeeding has not yet been established.
Formulation
Contains no artificial flavors or colorants. No gluten added.
All Native Remedies health products are especially formulated by experts in the field of natural health and are manufactured according to the highest pharmaceutical standards for maximum safety and effectiveness.
All-Natural
Promotes cardiovascular health
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1-2 capsules, 2-3 times daily.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
K Parve (Kosher) K-1604
Formula
K Parve (Kosher) K-1604
FDA Statement of Identity
Herbal Supplement
General Statements
Int'l.: +1-920-232-3275
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cholesto-Rite by Native Remedies label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cholesto-Rite by Native Remedies
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Formula
- › Red Yeast Rice
- › Rooibos
- › Guggul Gum
Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.
Cholesto-Rite by Native Remedies Drug Interactions
HelloPharmacist Interaction Report
Cholesto-Rite by Native Remedies contains three active ingredients, and we've found documented interactions with a significant number of medications.
The most serious concern is red yeast rice, which contains the statin drug lovastatin. If you take cyclosporine (used after transplants), combining it with this product could raise lovastatin levels dramatically—up to 20 times higher—and cause muscle breakdown (myopathy) or rhabdomyolysis, a dangerous condition where muscle tissue breaks down rapidly.
Read the full breakdown — every affected drug type, severity by severity
Red yeast rice also interacts with other statins (like atorvastatin or simvastatin), drugs that inhibit the liver enzyme CYP3A4, gemfibrozil (a cholesterol medication), high-dose niacin, and hepatotoxic drugs—all carrying moderate severity concerns around muscle damage, liver injury, or increased statin levels in your blood.
Rooibos, another ingredient, moderately inhibits several liver enzymes (CYP2C19, CYP1A2, CYP2D6, CYP2C9, CYP3A4) and may boost the effects of drugs broken down by those pathways. It also interacts with ACE inhibitors (blood pressure drugs), atorvastatin, and potentially other medications metabolized by those enzymes.
Guggul Gum interacts with propranolol and diltiazem (heart drugs), contraceptives, estrogens, blood thinners, thyroid hormone, and tamoxifen—potentially reducing the effect of some or increasing risk of bleeding or hormonal side effects.
Altogether, these interactions span 1,116 individual medications. Use the medication checker below to verify your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cholesto-Rite?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cholesto-Rite interact with 1,136 drugs. Click any drug to see the details.
3 of the 3 ingredients in Cholesto-Rite interact with drugs. Each result below shows which ingredient is responsible. Rooibos Guggul Gum Red Yeast Rice
Acetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionRooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Guggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionRooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylephrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Phenylephrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionRooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Guggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorzoxazone interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Chlorzoxazone, Codeine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Codeine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Codeine, Doxylamine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Codeine, Methocarbamol interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Guggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionRooibosCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Cholesto-Rite — through 3 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionGuggul GumCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
Read the full Guggul Gum + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dichloralantipyrine, Isometheptene interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dichloralphenazone, Isometheptene interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Dichlorophenazone, Isometheptane interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
Red Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Diphenhydramine interactionRooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Cholesto-Rite — through 2 ingredients. Tap an ingredient for the detail:
RooibosCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
Read the full Rooibos + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionRed Yeast RiceHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might increase the risk of liver damage.
Read the full Red Yeast Rice + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cholesto-Rite with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Rooibos
Ace Inhibitors (Aceis)
Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.
Atorvastatin (Lipitor)
Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.
Guggul Gum
Anticoagulant/Antiplatelet Drugs
Theoretically, guggul might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research and preliminary clinical studies suggest that guggul might have antiplatelet and anticoagulant effects.
Contraceptive Drugs
Theoretically, guggul might increase the risk of adverse effects when taken with contraceptive drugs.
In vitro research shows that guggul has estrogen-alpha receptor agonist activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, guggul might reduce the effects of CYP3A4 substrates.
In vitro research shows that guggul constituents known as guggulsterones can induce CYP3A4.
Diltiazem (Cardizem, Others)
Guggul might reduce the effects of diltiazem.
A small pharmacokinetic study shows that concomitant use of guggul with diltiazem reduces the bioavailability of diltiazem.
Estrogens
Theoretically, guggul might increase the risk of adverse effects when taken with estrogens.
In vitro research shows that guggul constituents known as guggulsterones have estrogen-alpha receptor agonist activity.
Propranolol (Inderal)
Guggul might reduce the effects of propranolol.
A small pharmacokinetic study shows that concomitant use of guggul with propranolol reduces the bioavailability of propranolol.
Rosuvastatin (Crestor)
Theoretically, guggul might increase the effects and adverse effects of rosuvastatin.
Animal research shows that guggul increases the bioavailability and hypolipidemic effects of rosuvastatin. The mechanism of this interaction is unclear.
Tamoxifen (Nolvadex)
Theoretically, guggul might interfere with tamoxifen therapy.
In vitro research shows that guggul has estrogen-alpha receptor agonist activity.
Thyroid Hormone
Theoretically, guggul might increase the risk for adverse effects when taken with thyroid hormone therapy.
Animal research suggests that guggul has thyroid-stimulating effects.
Red Yeast Rice
Cyclosporine (Neoral, Sandimmune)
Theoretically, taking red yeast rice in combination with cyclosporine might increase the risk of myopathy.
Red yeast rice contains varying levels of the statin drug lovastatin. Cyclosporine has been reported to increase plasma levels of lovastatin by 5- to 20-fold, resulting in reports of myopathy and rhabdomyolysis.
Cytochrome P450 3A4 (Cyp3A4) Inhibitors
Theoretically, drugs that inhibit the CYP3A4 enzymes might increase levels of lovastatin from red yeast rice.
Red yeast rice contains varying levels of the statin drug lovastatin, which is metabolized by CYP3A4. Combining red yeast rice with CYP3A4 inhibitors might increase serum levels of lovastatin from red yeast rice.
Gemfibrozil (Lopid)
Theoretically, taking red yeast rice in combination with gemfibrozil might increase the risk of rhabdomyolysis.
Red yeast rice contains varying levels of the statin drug lovastatin. Gemfibrozil has been reported to increase the risk of rhabdomyolysis when used in combination with lovastatin.
Hepatotoxic Drugs
Theoretically, concomitant use might increase the risk of liver damage.
Red yeast rice contains varying levels of the drug lovastatin. Lovastatin can cause liver damage in some people. Some clinical research suggests that supplements containing red yeast rice might increase liver enzyme levels in some, but not all, participants. Cases of acute hepatitis have been associated with red yeast rice. Combining it with hepatotoxic drugs might further increase this risk.
Hmg-Coa Reductase Inhibitors ("Statins")
Theoretically, taking red yeast rice with other statins might increase the risk of potential adverse effects.
Red yeast rice contains varying levels of the statin drug lovastatin and might result in supratherapeutic levels when used with other statins. Based on evaluation of data from the US Food and Drug Administration's adverse event reporting system (FAERS), it is recommended that red yeast rice products be avoided in people taking prescription statins.
Niacin
Theoretically, taking red yeast rice in combination with high-dose niacin might increase the risk of rhabdomyolysis.
Red yeast rice contains varying levels of the statin drug lovastatin and has been linked to reports of myopathy. Niacin has been reported to increase the risk of rhabdomyolysis when used in combination with lovastatin.
Brand information
Manufacturer and brand details for Cholesto-Rite, from the product label.
Native Remedies
See all Native Remedies products- Name
- Silver Star Brands
- City
- Oshkosh
- State
- WI
- ZipCode
- 54906
- Phone Number
- 1-877-289-1235
- Web Address
- www.nativeremedies.com
Cholesto-Rite by Native Remedies: Common Questions
Does Cholesto-Rite by Native Remedies interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does red yeast rice actually lower cholesterol?
What are the most common side effects I might feel?
Can I take this while pregnant or breastfeeding?
What is guggul gum, and why is it in this product?
Is there anything dangerous I should know about?
Why does product quality vary so much?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cholesto-Rite is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cholesto-Rite’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Red Yeast Rice
Interacts with 477 drugsRed yeast rice contains monacolin K, which is chemically identical to the prescription statin lovastatin, and it can lower LDL ('bad') cholesterol. Because of this, it carries the same risks...
Read the full Red Yeast Rice monograph → Herb & supplement monographRooibos
Interacts with 879 drugsRooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for he...
Read the full Rooibos monograph → Herb & supplement monographGuggul
Interacts with 757 drugsGuggul is a gum resin from the Commiphora wightii tree, long used in Ayurvedic medicine for cholesterol, joint, and skin problems. Modern studies are mixed and often low-quality, and it can...
Read the full Guggul monograph →Sources & How We Checked
Cholesto-Rite's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 75 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Red Yeast Rice 50 references
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- Heber D, Yip I, Ashley JM, et al. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr 1999;69:231-6. PubMed
- Wang J, Lu A, Chi J. Multicenter clinical trial of the serum lipid-lowering effects of a monascus purpureus (red yeast) rice preparation from traditional Chinese medicine. Cur Ther Res 1997;58:964-78. DOI
- Wigger-Alberti W, Bauer A, Hipler UC, Elsner P. Anaphylaxis due to Monascus purpureus-fermented rice (red yeast rice). Allergy 1999;54:1330-1.
- Prasad GV, Wong T, Meliton G, Bhaloo S. Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipient. Transplantation 2002;74:1200-1. PubMed
- Heber D, Lembertas A, Lu QY, et al. An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents. J Altern Complement Med 2001;7:133-9. PubMed
- Mueller PS. Symptomatic myopathy due to red yeast rice. Ann Intern Med 2006;145:474-5. PubMed
- Roselle H, Ekatan A, Tzeng J, et al. Symptomatic hepatitis associated with the use of herbal red yeast rice. Ann Intern Med 2008;149:516-7. PubMed
- Lapi F, Gallo E, Bernasconi S, et al. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. Br J Clin Pharmacol 2008;66:572-74. PubMed
- Becker DJ, Gordon RY, Halbert SC, et al. Red yeast rice for dyslipidemia in statin-intolerant patients: A randomized trial. Ann Intern Med 2009;150:830-9. PubMed
- Halbert SC, French B, Gordon RY, et al. Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. Am J Cardiol 2010;105:198-204. PubMed
- Gordon RY, Cooperman T, Obermeyer W, Becker DJ. Marked variability of monacolin levels in commercial red yeast rice products: buyer beware! Arch Intern Med 2010;170:1722-7. PubMed
- Karl M, Rubenstein M, Rudnick C, Brejda J. A multicenter study of nutraceutical drinks for cholesterol (evaluating effectiveness and tolerability). J Clin Lipidology 2012;6:150-158. PubMed
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- Grieco, A., Miele, L., Pompili, M., Biolato, M., Vecchio, F. M., Grattagliano, I., and Gasbarrini, G. Acute hepatitis caused by a natural lipid-lowering product: when "alternative" medicine is no "alternative" at all. J Hepatol 2009;50(6):1273-1277. PubMed
- Smith, D. J. and Olive, K. E. Chinese red rice-induced myopathy. South.Med J 2003;96(12):1265-1267. PubMed
- Liu, B. H., Wu, T. S., Su, M. C., Chung, C. P., and Yu, F. Y. Evaluation of citrinin occurrence and cytotoxicity in Monascus fermentation products. J Agric.Food Chem. 1-12-2005;53(1):170-175.
- Lin, C. C., Li, T. C., and Lai, M. M. Efficacy and safety of Monascus purpureus Went rice in subjects with hyperlipidemia. Eur J Endocrinol 2005;153(5):679-686. PubMed
- Zhao, S. P., Lu, Z. L., Du, B. M., Chen, Z., Wu, Y. F., Yu, X. H., Zhao, Y. C., Liu, L., Ye, H. J., and Wu, Z. H. Xuezhikang, an extract of cholestin, reduces cardiovascular events in type 2 diabetes patients with coronary heart disease: subgroup analysis
- Lu, Z., Kou, W., Du, B., Wu, Y., Zhao, S., Brusco, O. A., Morgan, J. M., Capuzzi, D. M., and Li, S. Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction. Am J Cardiol PubMed
- Li, J. J., Lu, Z. L., Kou, W. R., Chen, Z., Wu, Y. F., Yu, X. H., and Zhao, Y. C. Beneficial impact of Xuezhikang on cardiovascular events and mortality in elderly hypertensive patients with previous myocardial infarction from the China Coronary Secondary
- Li, J. J., Lu, Z. L., Kou, W. R., Chen, Z., Wu, Y. F., Yu, X. H., and Zhao, Y. C. Impact of Xuezhikang on coronary events in hypertensive patients with previous myocardial infarction from the China Coronary Secondary Prevention Study (CCSPS). Ann Med 2010 PubMed
- Li, J. J., Lu, Z. L., Kou, W. R., Chen, Z., Wu, Y. F., Yu, X. H., and Zhao, Y. C. Long-term effects of Xuezhikang on blood pressure in hypertensive patients with previous myocardial infarction: data from the Chinese Coronary Secondary Prevention Study (CC
- Liu, Z. L., Liu, J. P., Zhang, A. L., Wu, Q., Ruan, Y., Lewith, G., and Visconte, D. Chinese herbal medicines for hypercholesterolemia. Cochrane Database Syst Rev 2011;(7):CD008305. PubMed
- Chagas, G. M., Kluppel, M. L., Campello, Ade P., Buchi, Dde F., and de Oliveira, M. B. Alterations induced by citrinin in cultured kidney cells. Cell Struct.Funct. 1994;19(2):103-108. PubMed
- Krejci, M. E., Bretz, N. S., and Koechel, D. A. Citrinin produces acute adverse changes in renal function and ultrastructure in pentobarbital-anesthetized dogs without concomitant reductions in [potassium] plasma. Toxicology 1-8-1996;106(1-3):167-177. PubMed
- Blanc PJ, Laussac JP, Le Bars J, et al. Characterization of monascidin A from Monascus as citrinin. Int J Food Microbiol. 1995;27(2-3):201-213. PubMed
- Lu, Z. L., Xu, S., and Kou, W. R. The clinical observation of treatment of hyperlipidemia with different dose of Xuezhikang. National Symposium of Clinical Therapies for Cardiovascular Diseases 1995;1997:53-57.
- Bonovich, K., Colfer, H., Petoskey, M. I., and et al. A multi-center, self-controlled study of cholestin in subjects with elevated cholesterol. Journal of Investigative Medicine 1999;47(2):54A.
- Pisciotta, L., Boscarini, M., and Corio, R. Studi clinici su Normolip5, integratore alimentare per il controllo del colesterolo. Medicina Naturale 2004;68-70.
- Barrat E, Zaïr Y, Sirvent P, et al. Effect on LDL-cholesterol of a large dose of a dietary supplement with plant extracts in subjects with untreated moderate hypercholesterolaemia: a randomised, double-blind, placebo-controlled study. Eur J Nutr. 2013;52( PubMed
- Kumari S, Sherriff JM, Spooner D, Beckett R. Peripheral neuropathy induced by red yeast rice in a patient with a known small bowel gastrointestinal tumour. BMJ Case Rep. 2013;2013. PubMed
- Mazzanti G, Moro PA, Raschi E, Da Cas R, Menniti-Ippolito F. Adverse reactions to dietary supplements containing red yeast rice: assessment of cases from the Italian surveillance system. Br J Clin Pharmacol 2017;83(4):894-908. PubMed
- Gerards MC, Terlou RJ, Yu H, Koks CH, Gerdes VE. Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain - a systematic review and meta-analysis. Atherosclerosis. 2015;240(2):415-23. doi: 10.101 PubMed
- Venhuis BJ, van Hunsel F, van de Koppel S, Keizers PH, Jeurissen SM, De Kaste D. Pharmacologically effective red yeast rice preparations marketed as dietary supplements illustrated by a case report. Drug Test Anal. 2016;8(3-4):315-8. doi: 10.1002/dta.1929 PubMed
- Raschi E, Girardi A, Poluzzi E, et al. Adverse events to food supplements containing red yeast rice: comparative analysis of FAERS and CAERS reporting systems. Drug Saf 2018;41(8):745-52. doi: 10.1007/s40264-018-0661-3. PubMed
- Mercurio V, Pucci G, Bosso G, et al. A nutraceutical combination reduces left ventricular mass in subjects with metabolic syndrome and left ventricular hypertrophy: A multicenter, randomized, double-blind, placebo-controlled trial. Clin Nutr. 2020;39(5):1 PubMed
- Prescribing Information. Mevacor (lovastatin). Whitehouse Station, NJ: Merck & Co., Inc., February 2012.
- Cicero AFG, Kennedy C, Knezevic T, et al. Efficacy and Safety of Armolipid Plus(®): An Updated PRISMA Compliant Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials. Nutrients 2021;13(2):638. PubMed
- Cicero AFG, Bove M, Cincione RI, Fogacci F, Veronesi M. Effect of combined lipid-lowering and antioxidant nutraceutical on plasma lipids, endothelial function, and estimated cardiovascular disease risk in moderately hypercholesterolemic patients: a double
- 7-20-21 FDA Drug Safety Communication. FDA requests removal of strongest warning against using cholesterol-lowering statins during pregnancy; still advises most pregnant patients should stop taking statins. Available at: https://www.fda.gov/drugs/drug-s
- García-García MD, Bellido Muñoz F, Cordero Ruiz P, Caunedo Álvarez Á. Drug-induced liver injury associated to red yeast rice. Rev Esp Enferm Dig 2023. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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