Cinnamon 1,500 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cinnamon 1,500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cinnamon 1,500 mg is a dietary supplement by Puritan's Pride with 2 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cinnamon 1,500 mg by Puritan's Pride
Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamon 1,500 mg by Puritan's Pride — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cinnamon 1,500 mg by Puritan's Pride
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 2 active ingredients: cinnamon (the common spice) and cinnamon bark extract. Both come from cassia cinnamon and contribute the same active compounds.
The product is 1,500 mg total per serving. It also includes inactive ingredients — cellulose, silica, and magnesium stearate — which are standard capsule fillers and binders.
Does it work?
Couldn't assess
The evidence isn't established for any of cinnamon's traditional uses. The data we hold shows insufficient reliable evidence to rate it for amenorrhea, angina, common cold, diabetes, diarrhea, or dyslipidemia (high cholesterol).
That doesn't mean it doesn't work; it means large, rigorous studies backing it up aren't in our monograph yet.
How safe is it?
Well-documented data
Cinnamon is generally well tolerated at food amounts — the spice in your kitchen is safe. At supplement doses like this one, especially over the long term, there's concern about coumarin, a compound in cassia cinnamon that can harm the liver.
Very high coumarin intakes (50–7,000 mg daily) have caused liver damage in people, though it reversed when stopped. In clinical trials at moderate to high cinnamon doses (360 mg to 12 grams daily for 3 months), liver enzyme levels stayed normal, but caution is warranted with ongoing use.
During pregnancy, food amounts of cinnamon are fine, but avoid medicinal or high-dose supplement doses — the safety data isn't there. Breastfeeding safety data is also limited.
A small number of people reported skin rashes or allergic reactions, and one person with a documented cinnamon allergy developed severe eyelid dermatitis from dietary cinnamon.
Meds to double-check
Moderate interaction found
Double-check this product if you take diabetes medications — cinnamon may lower blood sugar and require a dose adjustment. Also check if you take any drugs that stress the liver (hepatotoxic drugs), since cinnamon could add to that risk over time.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take diabetes medications or drugs that stress your liver, talk with your pharmacist before starting this product. If you have a cinnamon allergy, skip it.
For most others, this dose is generally well tolerated short-term, but long-term use warrants caution due to coumarin content. Run your exact medications through the checker on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cinnamon 1,500 mg, straight from the product label.
| Brand | Puritan's Pride |
|---|---|
| Barcode (UPC) | 025077140206 |
| Net contents | 100 Rapid Release Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 287285 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cinnamon 1,500 mg by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cinnamon | 200 mg | -- |
| Cinnamon Bark Extract | 300 mg | -- |
Other ingredients: Cellulose, Silica, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.
Supports sugar metabolism
Vegetarian
No artificial color, flavor or sweetener, no sugar, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.
Precautions
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if seal under cap is broken or missing.
Storage
Store at room temperature.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
To reorder item # 14020 www.puritan.com 1-800-645-1030
Brand IP Statement(s)
Copyright 2022 Puritan's Pride, Inc.
Seals/Symbols
QA Quality Assured
Formula
Cinnamon 1,500 mg per 3 capsules
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Directions: For adults, take one (1) capsule three times daily, preferably with meals.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cinnamon 1,500 mg by Puritan's Pride label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cinnamon 1,500 mg by Puritan's Pride
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Cinnamon
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon monograph & interactionsCinnamon Bark Extract
Interacts with442 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon Bark Extract monograph & interactionsOther (inactive) ingredients: Cellulose, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Cinnamon 1,500 mg by Puritan's Pride Drug Interactions
HelloPharmacist Interaction Report
Cinnamon 1,500 mg by Puritan's Pride does interact with certain medications.
The main concern is with drugs that stress the liver (hepatotoxic drugs) — cinnamon contains coumarin, which in large amounts over time could add to that stress. The product also may lower blood sugar, so if you take diabetes medications, there's a risk of too-low blood sugar (hypoglycemia) and you might need a dose adjustment.
Read the full breakdown — every affected drug type, severity by severity
Although the dose in this product is moderate, the safety data flags concern about long-term use of high-dose cinnamon supplements because of coumarin buildup. In clinical trials at higher doses, liver enzyme levels stayed normal, but animal studies show coumarin can harm the liver, and very high coumarin intakes (50–7,000 mg daily) have caused liver damage in humans that reversed when stopped.
Additionally, side effects in trials have been rare — one rash in one person at 1 gram daily, and one report of low blood sugar with a seizure (though the link to cinnamon wasn't clear). A few people with cinnamon allergies developed skin reactions from dietary cinnamon.
Altogetherther, these interactions span 425 individual medications. Check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cinnamon 1,500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cinnamon 1,500 mg interact with 442 drugs. Click any drug to see the details.
1 of the 2 ingredients in Cinnamon 1,500 mg interact with drugs. Each result below shows which ingredient is responsible. Cinnamon
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Cinnamon Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Cinnamon 1,500 mg — through 1 ingredient. Tap an ingredient for the detail:
Cinnamon Bark ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon Bark Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cinnamon 1,500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Cinnamon
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Brand information
Manufacturer and brand details for Cinnamon 1,500 mg, from the product label.
Puritan's Pride
See all Puritan's Pride products- Name
- Puritan's Pride, Inc.
- City
- Ronkonkoma
- State
- NY
- ZipCode
- 11779
- Phone Number
- 1-800-645-1030
- Web Address
- www.puritan.com
Cinnamon 1,500 mg by Puritan's Pride: Common Questions
Does Cinnamon 1,500 mg by Puritan's Pride interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is cinnamon safe during pregnancy?
Can this help with diabetes?
Is cinnamon safe long-term?
What's in this product besides cinnamon?
Who shouldn't take this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cinnamon 1,500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cinnamon 1,500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cinnamon 1,500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 20 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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