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Dietary supplement

Cinnamonforce Ingredients & Drug Interactions

by New Chapter

Cinnamonforce label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cinnamonforce against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cinnamonforce is a dietary supplement by New Chapter with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cinnamonforce by New Chapter

Ask about any prescription or over-the-counter medication and we check it for interactions with Cinnamonforce by New Chapter — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cinnamonforce by New Chapter

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Cinnamon” is listed as a grouped ingredient — the label gives one combined amount (140 mg) without saying how much of each component you get.

Cinnamonforce contains three active ingredients: two forms of cinnamon extract (one made using a hydroethanolic method, one using supercritical extraction) and cinnamaldehyde, which is the compound responsible for cinnamon's spicy flavor and aroma. The product is delivered in a softgel capsule made with olive oil, beeswax, and a gelatin shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: blood sugar balance and healthy weight management.
  • We looked for evidence on: Diabetes, Dyslipidemia, Impaired glucose tolerance (prediabetes), Obesity, metabolic syndrome, insulin sensitivity.
  • The closest evidence on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Cassia Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Obesity, Impaired glucose tolerance (prediabetes).

The evidence for cinnamon in this product isn't established for any of the uses we have data on — amenorrhea, angina, common cold, diabetes, diarrhea, and high cholesterol all carry a rating of insufficient reliable evidence. That doesn't mean cinnamon doesn't work; it means the studies we hold aren't strong enough to say one way or the other.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cinnamon is generally well tolerated in the amounts you'd eat in food. At supplement doses — especially high doses over a long time — there's concern about coumarin, which can harm the liver.

In clinical trials using cinnamon doses of 360 mg to 12 grams daily for 3 months, liver enzyme levels didn't show significant damage, but very high coumarin intake (50–7000 mg/day) has caused reversible liver damage in humans. A small number of people have reported rash or allergic skin reactions to cinnamon, and one trial participant experienced low blood sugar (hypoglycemia) while taking cinnamon, though the link wasn't certain.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your diabetes medications (insulin, sulfonylureas, and other blood-sugar drugs) and any medications that can harm the liver before starting Cinnamonforce. Cinnamon may lower blood sugar and add to liver strain at high doses.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on diabetes medication or take drugs that affect your liver, check with us or your doctor before starting this product — cinnamon can lower blood sugar and may stress the liver at high doses. The evidence for what cinnamon actually does isn't strong yet.

Food-amount cinnamon is safe in pregnancy and breastfeeding, but avoid medicinal doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cinnamonforce, straight from the product label.

Brand New Chapter
Net contents 60 Hexane-Free Softgel Capsule(s)
Market status On market
Date entered into DSLD Nov 25, 2011
DSLD ID 2398
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cinnamonforce by New Chapter, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Proprietary Blend0 NP--
Cinnamaldehyde16 mg--
Cinnamon140 mg--
hydroethanolic Cinnamon extract94 mg--
supercritical Cinnamon extract46 mg--

Other ingredients: Olive oil-extra virgin, yellow Beeswax, Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule at the end of each of the two largest meals of the day.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

4038-02-01

General Statements

Blood Sugar Balance* - Use as part of your diet to promote healthy weight management* - Promotes normal blood lipid profiles already in the normal range*

Helps Maintain Blood Sugar Already in Normal Range*

Please recycle this bottle after use.

The Exotic Spice of Cinnamon Promotes Healthy Weight Management* From the earliest herbal writings almost 5,000 years ago, cinnamon has imparted its exotic flavor to modern civilization. The two principal species of cinnamon, verum and aromaticum, were treasured for enhancing food as well as a host of important health applications. Research at the United States Department of Agriculture (USDA) and other prestigious institutions suggest that cinnamon possesses a unique power amongst botanicals - it assists the body’s conversion of sugar (glucose) into energy. As part of your healthy diet and lifestyle,

Precautions

If you are nursing, pregnant, or considering pregnancy, you should consult your health care practitioner prior to using this product.

Caution: As with any dietary or herbal supplement, you should advise your health care practitioner of the use of this product.

Formulation

Naturally gluten free.

Our premium softgel capsules are prepared without any chemical solvents and are prion free.

FDA Statement of Identity

DIETARY SUPPLEMENT

Brand IP Statement(s)

Cinnamonforce promotes healthy weight management by helping glucose do its primary work - creating immediate cellular energy - rather than ending up as “stored” potential energy in the form of fat deposits.*

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cinnamonforce by New Chapter label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cinnamonforce label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cinnamonforce by New Chapter

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: Olive oil-extra virgin, Yellow Beeswax, Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cinnamonforce by New Chapter Drug Interactions

Want to check YOUR meds against Cinnamonforce?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

Cinnamon 442

Individual Drug Interactions

The ingredients in Cinnamonforce interact with 442 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cinnamonforce interact with drugs. Each result below shows which ingredient is responsible. Cinnamon

Each ingredient & the kinds of drugs it affects

For each ingredient in Cinnamonforce with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cinnamon2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
Cinnamon full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cinnamonforce, from the product label.

New Chapter

See all New Chapter products
Web Address
newchapter.com
Pharmacist Counseling Corner

Cinnamonforce by New Chapter: Common Questions

Does Cinnamonforce by New Chapter interact with any medications?
Yes. Based on its ingredients, Cinnamonforce has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cinnamonforce contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or nursing?
Food-amount cinnamon is considered likely safe in pregnancy and breastfeeding. But this is a supplement at higher doses, so the safety data is limited. The advice is to stick to food amounts and avoid medicinal or concentrated supplement doses while pregnant or nursing. Talk with your doctor for personalized guidance.
Can cinnamon really help with blood sugar or diabetes?
The evidence we have on cinnamon for diabetes is insufficient — we can't say whether it works or doesn't. What we do know is that cinnamon may lower blood sugar, which is why it matters if you're on diabetes medication.
Is cinnamon bad for the liver?
Cinnamon in food amounts is generally safe. At supplement doses over long periods, there's concern about coumarin, a compound in cinnamon that can damage liver tissue in animal studies. In people taking cinnamon supplement doses (360 mg to 12 grams daily) for 3 months in clinical trials, liver damage wasn't seen, but very high coumarin doses have caused reversible liver harm in humans.
What's cinnamaldehyde?
Cinnamaldehyde is the main compound that gives cinnamon its spicy taste and smell. We don't have interaction data on file for it, so we can't say how it reacts with medications.
Has anyone had side effects from cinnamon supplements?
In clinical trials, a small number of people reported a rash, and there are a few case reports of allergic skin reactions in people sensitive to cinnamon. One trial participant experienced low blood sugar while taking cinnamon, though it's unclear if cinnamon caused it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cinnamonforce label
Go deeper

The Full Monographs Behind Cinnamonforce’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cassia Cinnamon

Interacts with 442 drugs

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...

Read the full Cassia Cinnamon monograph →
Sources

Sources & How We Checked

Cinnamonforce's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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