Clear Muscle Ingredients & Drug Interactions
by MuscleTech
What is this page for?
First and foremost: checking Clear Muscle against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Clear Muscle is a dietary supplement by MuscleTech with 2 active ingredients. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Clear Muscle by MuscleTech
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Clear Muscle contains 2 active ingredients: betaine anhydrous and BetaTOR. Betaine anhydrous is an amino acid compound that your body uses in the production of creatine and may support muscle function and athletic performance.
We don't have detailed information on file about BetaTOR's role. The product also contains several inactive ingredients — glycerin, modified food starch, carrageenan, sorbitol, purified water, and natural flavors — which are fillers and binders that give the softgel its form and texture.
Does it work?
Not established
The evidence for betaine anhydrous is mixed. It's considered effective for homocystinuria (a rare metabolic disorder affecting blood amino acids), and possibly effective for lowering homocysteine levels in the blood.
For athletic performance, muscle gain, and other uses people often take it for, the evidence isn't well established in our data — we don't have reliable evidence to rate betaine for nonalcoholic fatty liver disease, colorectal polyp prevention, depression, or reflux. We have no effectiveness data on file for BetaTOR.
How safe is it?
Well-documented data
Betaine anhydrous is generally well tolerated at studied doses, but safety data isn't complete, so check with your doctor before starting. The most common side effects are body odor, diarrhea, nausea, vomiting, GI upset, and elevated cholesterol — a small number of people have reported these.
Rarely, cerebral swelling has been reported. Pregnancy safety data isn't available, so talk to your OB or pharmacist if you're pregnant or planning to be.
Breastfeeding safety isn't well established either — caution is advised if you're nursing. We have no safety data on file for BetaTOR.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check. However, we couldn't verify safety with medications for BetaTOR, so check with us before adding this product to your routine if you're on any prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
If you're looking for support with homocysteine levels or homocystinuria, betaine anhydrous is worth discussing with your doctor. For athletic performance or muscle gain, the evidence isn't clear.
Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or take regular medications — and mention that we couldn't check one of the two ingredients in this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Clear Muscle, straight from the product label.
| Brand | MuscleTech |
|---|---|
| Barcode (UPC) | 631656610154 |
| Net contents | 42 Liquid Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2024 |
| DSLD ID | 322234 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Clear Muscle by MuscleTech, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Betaine Anhydrous | 250 mg | -- |
| BetaTOR | 1000 mg | -- |
Other ingredients: Glycerin, Food Starch, Modified, Carrageenan, Sorbitol, Water, Purified, Natural Flavors
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
From Americas #1 selling supplement company
Formulation
HMB Free Acid
Performance & recovery amplifier Enhance strength Build muscle Accelerate recovery
Made in the U.S.A. from international ingredients.
Formula
Highest grade HMB for lean muscle & recovery 1,000mg BetaTOR
FDA Statement of Identity
Dietary Supplement
Precautions
Contains coconut ingredients.
Warning: For adult use only.
Do not use if pregnant or nursing.
Consult a medical doctor before use if you have a medical condition and before starting a diet or exercise program.
Keep out of reach of children.
Contains bioengineered food ingredients.
Do not use if packaging has been tampered with.
Suggested/Recommended/Usage/Directions
Directions of use: Take 1 serving (1 softgel) 3 times daily (in the morning, mid-afternoon and evening). On workout days, take 1 of these servings 30 minutes before training. Do not exceed 3 servings (3 softgels) in a 24-hour period. To maximize your results, use the exact same training protocol as the subjects in the 12-week study. Visit muscletech.com/trainhard
Storage
Store in a cool, dry place (60 degrees F to 80 degrees F).
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
BetaTOR (HMB free acid) BetaTOR is a registered trademark of Metabolic Technologies, LLC and use is licensed from Metabolic Technologies, LLC. Uses of HMB are covered by pending patent applications owned by Metabolic Technologies, LLC.
Copyright 2021.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Clear Muscle by MuscleTech label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Clear Muscle by MuscleTech
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Liquid Softgel Capsule(s) Dosage formSoftgel Capsule Servings per container84 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Betaine Anhydrous
No knowninteractions
Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...
Betaine Anhydrous monograph & interactionsBetaTOR
Other (inactive) ingredients: Glycerin, Food Starch, Modified, Carrageenan, Sorbitol, Water, Purified, Natural Flavors. These complete the product’s ingredient list but are not active constituents.
Clear Muscle by MuscleTech Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Clear Muscle. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Clear Muscle, from the product label.
MuscleTech
See all MuscleTech products- Name
- Iovate Health Sciences U.S.A. Inc.
- Street Address
- 1105 Market Street, Suite 1330
- City
- Wilmington
- State
- DE
- ZipCode
- 19801
Clear Muscle by MuscleTech: Common Questions
Does Clear Muscle by MuscleTech interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this give me body odor?
Is this safe during pregnancy?
Can I take this while breastfeeding?
What does betaine anhydrous actually do?
What are the most common side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Clear Muscle is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Clear Muscle’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Clear Muscle's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Betaine Anhydrous 11 references
- Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
- Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
- Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
- McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
- Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
- Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
- Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
- Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
- Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
- Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
- Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC