Cognizin Capsules 250 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cognizin Capsules 250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cognizin Capsules 250 mg is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for memory and thinking, brain health and aging, stroke recovery support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cognizin Capsules 250 mg by Nootropics Depot
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: citicoline (branded as Cognizin). Citicoline is a compound that your body produces naturally and that plays a role in brain cell function and energy production.
Each capsule delivers 250 mg. The capsule itself is made from vegetable cellulose, and the formula includes magnesium stearate as an inactive ingredient.
Does it work?
Moderate evidence
The evidence for citicoline is mixed. It's rated possibly effective for age-related cognitive decline and for glaucoma.
For stroke, the evidence suggests it may not help. For Alzheimer's disease, traumatic brain injury, and cardiac arrest, we don't have enough reliable evidence to say whether it works or not.
How safe is it?
Well-documented data
Citicoline is generally well tolerated in studies, but long-term safety hasn't been fully established. The most common side effects reported when taken by mouth include abdominal pain, back pain, blurred vision, constipation, diarrhea, swelling, headache, insomnia, nausea, and rash — though these occurred in a small number of trial participants.
The safety data advises against use during pregnancy and while breastfeeding because there isn't enough information to know it's safe in those situations; talk with your doctor or pharmacist for personalized advice if either applies to you.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient in this product. That said, always run your full medication list through the checker on this page or confirm with your doctor or pharmacist before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Cognizin may be worth considering if you're interested in cognitive support, especially for age-related decline, though the evidence is still developing. It has no documented drug interactions, which is a plus.
Long-term safety isn't fully known, and it's not recommended in pregnancy or breastfeeding — check with your own doctor or pharmacist before starting, especially if you're pregnant, nursing, or have specific health concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cognizin Capsules 250 mg, straight from the product label.
| Brand | Nootropics Depot |
|---|---|
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 232121 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cognizin Capsules 250 mg by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cognizin | 250 mg | -- |
Other ingredients: Magnesium Stearate, Vegetable Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Citicoline
FDA Statement of Identity
Dietary Supplement
Precautions
Disclaimer: Always consult with a qualified health physician before taking any new dietary supplement.
Warning: Keep out of reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).
Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions, and/or taking prescription drug(s) or OTC medication(s).
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.
Brand IP Statement(s)
Cognizin is a registered trademark of Kyowa Hakko Bio Co. Ltd.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1 capsule 1-2 times daily.
Storage
Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cognizin Capsules 250 mg by Nootropics Depot label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cognizin Capsules 250 mg by Nootropics Depot
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Cognizin
No knowninteractions
Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken f...
Cognizin monograph & interactionsOther (inactive) ingredients: Magnesium Stearate, Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.
Cognizin Capsules 250 mg by Nootropics Depot Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cognizin Capsules 250 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cognizin Capsules 250 mg, from the product label.
Nootropics Depot
See all Nootropics Depot products- Name
- Nootropics Depot
- Street Address
- 8380 S. Kyrene Rd. Ste. 110
- City
- Tempe
- State
- AZ
- ZipCode
- 85284
- Web Address
- nootropicsdepot.com
Cognizin Capsules 250 mg by Nootropics Depot: Common Questions
Does Cognizin Capsules 250 mg by Nootropics Depot interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is Cognizin, and what's it supposed to do?
Can I take this if I'm pregnant or breastfeeding?
What side effects might I experience?
Does this interact with my medications?
How long have people safely used this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cognizin Capsules 250 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cognizin Capsules 250 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cognizin Capsules 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Citicoline 11 references
- Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8. PubMed
- Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;(2):CD000269. PubMed
- Conant R, Schauss AG. Therapeutic applications of citicoline for stroke and cognitive function in the elderly: A review of the literature. Altern Med Rev 2004;9:17-31.
- Warach, S., Pettigrew, L. C., Dashe, J. F., Pullicino, P., Lefkowitz, D. M., Sabounjian, L., Harnett, K., Schwiderski, U., and Gammans, R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 0 DOI
- Lukas, S. E., Kouri, E. M., Rhee, C., Madrid, A., and Renshaw, P. F. Effects of short-term citicoline treatment on acute cocaine intoxication and cardiovascular effects. Psychopharmacology.(Berl.) 2001;157(2):163-167. PubMed
- Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A., and Aylward, M. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Arzneimittelforschung. 1983;33(7A):1061-1065.
- Clark BC, Georgekutty J, Berul CI. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. J Pediatr 2015;167(3):757-61.e1. PubMed
- Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. 2
- Castagna A, Manzo C, Fabbo A, Lacava R, Ruberto C, Ruotolo G. The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease. Clin Drug Investig. 2021 Feb;41(2):177-182. PubMed
- Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res 2021;143:215-221. PubMed
- Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr 2021;151(8):2153-2160. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC