No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

TruCDP Ingredients & Drug Interactions

by PEScience

TruCDP label
See full label image
Capsule Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking TruCDP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

TruCDP is a dietary supplement by PEScience with 1 active ingredient. Its ingredients are commonly taken for memory and thinking, brain health and aging, stroke recovery support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of TruCDP by PEScience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TruCDP is a single-ingredient product: it contains CDP-Choline, also known as citicoline, a compound that plays a role in brain cell structure and function. The rest of the capsule is made up of inactive ingredients — cellulose, gelatin, magnesium stearate, silicon dioxide, and titanium dioxide color — which are standard fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Memory, brain health, and cognitive function.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD), Cerebrovascular disease, Parkinson disease, Stroke — and 4 related terms.
  • The strongest evidence on file: Citicoline is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Citicoline is rated "Possibly Ineffective" for Stroke.
  • Also on file: Citicoline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD), Cerebrovascular disease, Vascular dementia, and more.

The evidence for CDP-Choline is mixed. It's rated possibly effective for age-related cognitive decline and glaucoma.

For stroke, the data suggests it's likely ineffective. For Alzheimer disease, traumatic brain injury, and cardiac arrest, there isn't enough reliable evidence yet to say whether it works or not.

The evidence, ingredient by ingredient Citicoline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

CDP-Choline is generally well tolerated when taken by mouth, though long-term safety hasn't been fully established yet. The most common side effects in studies were abdominal pain, back pain, blurred vision, constipation, diarrhea, swelling, headache, trouble sleeping, nausea, and rash — but these occurred in a small number of participants.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know it's safe in those situations; talk with your doctor or pharmacist for personalized guidance if either applies to you.

Side effects, ingredient by ingredient Citicoline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we could check. That said, run your exact prescriptions through the interaction checker on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

TruCDP might be worth considering if you're interested in cognitive support or have age-related cognitive concerns, since the evidence leans toward possibly effective there. If you're pregnant, breastfeeding, or planning to take it long-term, check in with your pharmacist first — the safety data is incomplete for pregnancy and lactation, and long-term effects aren't fully known.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about TruCDP, straight from the product label.

Brand PEScience
Barcode (UPC) 040232199622
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2016
DSLD ID 57539
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for TruCDP by PEScience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
040232199622
IngredientAmount% DV
CDP-Choline250 mg--

Other ingredients: Cellulose, Gelatin, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide color

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Precautions

Consult with your physician before using this product, especially if you are using any prescription or over the counter medication or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

WARNING: This product is only intended to be consumed by healthy adults 18 years of age or older.

Discontinue use 2 weeks prior to surgery. Discontinue use and consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule daily.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

30 Capsules 1 Powerful Ingredient

Superior Essentials

Cognitive Aid Formulated From Science

~ Powerful Nootropic ~ Cognition Support ~ Attention Support

Formula

250 mg Citicoline

~ 250mg CDP-Choline (Citricoline)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

TruCDP by PEScience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

TruCDP label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in TruCDP by PEScience

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

CDP-Choline

No known
interactions
250 mg per serving Form: Citicoline

Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken f...

CDP-Choline monograph & interactions

Other (inactive) ingredients: Cellulose, Gelatin, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide color. These complete the product’s ingredient list but are not active constituents.

Interaction report

TruCDP by PEScience Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in TruCDP. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for TruCDP, from the product label.

PEScience

See all PEScience products
Name
Physique Enhancing Science
Street Address
3665 East Bay Dr #204-155
City
Largo
State
FL
ZipCode
33771
Phone Number
888-885-0195
Web Address
PESCIENCE.COM
Pharmacist Counseling Corner

TruCDP by PEScience: Common Questions

Does TruCDP by PEScience interact with any medications?
We do not currently list a known interaction for the mapped ingredients in TruCDP. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
TruCDP contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is CDP-Choline safe to take while I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know it's safe in those situations. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or breastfeeding.
What side effects should I watch for?
CDP-Choline is generally well tolerated, but some people in studies experienced abdominal pain, back pain, blurred vision, constipation, diarrhea, headache, trouble sleeping, nausea, or rash. Most of these were uncommon.
Does this product really work for memory or brain health?
The evidence is strongest for age-related cognitive decline and glaucoma, where it's rated possibly effective. For Alzheimer disease and traumatic brain injury, there isn't enough reliable evidence yet. For stroke, the evidence suggests it's likely not effective.
What is CDP-Choline, exactly?
It's also called citicoline — a compound your brain normally makes that helps build and maintain brain cell structure. It's thought to support brain function, which is why it's used for cognitive and neurological concerns.
Is long-term use safe?
The studies show it's well tolerated, but long-term safety hasn't been fully established yet. If you're planning to take it for months or longer, check with your pharmacist about what we know and what we don't.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if TruCDP is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

TruCDP label
Go deeper

The Full Monographs Behind TruCDP’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Citicoline

Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken for memory, focus, and brain aging, and s...

Read the full Citicoline monograph →
Sources

Sources & How We Checked

TruCDP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Citicoline 11 references
  1. Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8. PubMed
  2. Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;(2):CD000269. PubMed
  3. Conant R, Schauss AG. Therapeutic applications of citicoline for stroke and cognitive function in the elderly: A review of the literature. Altern Med Rev 2004;9:17-31.
  4. Warach, S., Pettigrew, L. C., Dashe, J. F., Pullicino, P., Lefkowitz, D. M., Sabounjian, L., Harnett, K., Schwiderski, U., and Gammans, R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 0 DOI
  5. Lukas, S. E., Kouri, E. M., Rhee, C., Madrid, A., and Renshaw, P. F. Effects of short-term citicoline treatment on acute cocaine intoxication and cardiovascular effects. Psychopharmacology.(Berl.) 2001;157(2):163-167. PubMed
  6. Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A., and Aylward, M. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Arzneimittelforschung. 1983;33(7A):1061-1065.
  7. Clark BC, Georgekutty J, Berul CI. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. J Pediatr 2015;167(3):757-61.e1. PubMed
  8. Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. 2
  9. Castagna A, Manzo C, Fabbo A, Lacava R, Ruberto C, Ruotolo G. The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease. Clin Drug Investig. 2021 Feb;41(2):177-182. PubMed
  10. Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res 2021;143:215-221. PubMed
  11. Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr 2021;151(8):2153-2160. PubMed

See these in context on the Citicoline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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