Cognizin Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cognizin Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cognizin Powder is a dietary supplement by Nootropics Depot with 1 active ingredient. Its ingredients are commonly taken for memory and thinking, brain health and aging, stroke recovery support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cognizin Powder by Nootropics Depot
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This powder contains one active ingredient: Cognizin, which is a branded form of citicoline. Citicoline is a compound your body naturally produces; it plays a role in brain cell structure and function.
There are no inactive fillers or other ingredients listed in this product.
Does it work?
Moderate evidence
The evidence for citicoline is mixed and depends on what you're taking it for. It's rated possibly effective for age-related cognitive decline and glaucoma.
For stroke, the evidence suggests it may not be effective. For Alzheimer disease, traumatic brain injury, and cardiac arrest, we don't have enough reliable evidence to rate it — the studies aren't conclusive enough to say whether it works.
How safe is it?
Well-documented data
Citicoline is generally well tolerated in the studies we have, though long-term safety hasn't been fully established. The most common side effects reported with oral use are abdominal pain, back pain, blurred vision, constipation, diarrhea, swelling, headache, insomnia, nausea, and rash — though these appear in only a small number of trial participants.
The safety data advises against use during pregnancy and while breastfeeding due to insufficient information.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That doesn't mean interactions can't happen — it means we haven't found evidence of them in the studies we hold.
Run your exact medications through the checker on this page or confirm with your own doctor or pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Cognizin may be worth considering if you're interested in supporting age-related cognitive changes or eye health, though the evidence is limited. If you're pregnant, nursing, or have any health conditions, talk it over with your doctor or pharmacist first to see if it fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cognizin Powder, straight from the product label.
| Brand | Nootropics Depot |
|---|---|
| Net contents | 0.35 Ounce(s); 10 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2021 |
| DSLD ID | 251096 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cognizin Powder by Nootropics Depot, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cognizin | 250 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
10 gram sample
Disclaimer: Transfer scoops are not accurate. A mg scale is needed to accurately measure dosages.
Formula
Citicoline
Nootropics Depot's Citicoline contains Cognizin Citicoline.
FDA Statement of Identity
Dietary Supplement
Precautions
Always consult with a qualified health physician before taking any new dietary supplement.
Warning: Keep out of reach of children. Do not take if under 18, pregnant/nursing, have any medical conditions or taking RX/OTC drugs.
Do not take if under 18, pregnant/nursing, have any medical conditions or taking RX/OTC drugs.
FDA Disclaimer Statement
This product is not intended to diagnose, treat, cure or prevent any diseases. These statements have not been evaluated by the Food & Drug Administration.
Brand IP Statement(s)
Cognizin is a registered trademark of Kyowa Hakko Bio Co., Ltd.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 250 mg 1-2 times daily.
Storage
Storage: Store in a cool and dry place. Keep away from direct sunlight and heat.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cognizin Powder by Nootropics Depot label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cognizin Powder by Nootropics Depot
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size250 mg Dosage formPowder Servings per container40 Amounts shown are per serving.
Cognizin
No knowninteractions
Citicoline is a naturally occurring compound involved in making brain cell membranes and the messenger chemical acetylcholine. It is popularly taken f...
Cognizin monograph & interactionsCognizin Powder by Nootropics Depot Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cognizin Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cognizin Powder, from the product label.
Nootropics Depot
See all Nootropics Depot products- Name
- Nootropics Depot
- Street Address
- 8380 S. Kyrene Rd. Ste. 110
- City
- Tempe
- State
- AZ
- ZipCode
- 85284
- Web Address
- nootropicsdepot.com
Cognizin Powder by Nootropics Depot: Common Questions
Does Cognizin Powder by Nootropics Depot interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Cognizin if I'm pregnant or breastfeeding?
What are the most common side effects?
Does it actually work for memory and brain health?
Is this safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cognizin Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cognizin Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cognizin Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Citicoline 11 references
- Spiers PA, Myers D, Hochanadel GS, et al. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8. PubMed
- Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev 2005;(2):CD000269. PubMed
- Conant R, Schauss AG. Therapeutic applications of citicoline for stroke and cognitive function in the elderly: A review of the literature. Altern Med Rev 2004;9:17-31.
- Warach, S., Pettigrew, L. C., Dashe, J. F., Pullicino, P., Lefkowitz, D. M., Sabounjian, L., Harnett, K., Schwiderski, U., and Gammans, R. Effect of citicoline on ischemic lesions as measured by diffusion-weighted magnetic resonance imaging. Citicoline 0 DOI
- Lukas, S. E., Kouri, E. M., Rhee, C., Madrid, A., and Renshaw, P. F. Effects of short-term citicoline treatment on acute cocaine intoxication and cardiovascular effects. Psychopharmacology.(Berl.) 2001;157(2):163-167. PubMed
- Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A., and Aylward, M. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Arzneimittelforschung. 1983;33(7A):1061-1065.
- Clark BC, Georgekutty J, Berul CI. Myocardial ischemia secondary to synthetic cannabinoid (K2) use in pediatric patients. J Pediatr 2015;167(3):757-61.e1. PubMed
- Ghajar A, Gholamian F, Tabatabei-Motlagh M, et al. Citicoline (CDP-choline) add-on therapy to risperidone for treatment of negative symptoms in patients with stable schizophrenia: a double-blind, randomized placebo-controlled trial. Hum Psychopharmacol. 2
- Castagna A, Manzo C, Fabbo A, Lacava R, Ruberto C, Ruotolo G. The CITIMERIVA Study: CITIcoline plus MEmantina plus RIVAstigmine in Older Patients Affected with Alzheimer's Disease. Clin Drug Investig. 2021 Feb;41(2):177-182. PubMed
- Jeong H, Yoon S, Sung YH, et al. Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res 2021;143:215-221. PubMed
- Nakazaki E, Mah E, Sanoshy K, Citrolo D, Watanabe F. Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutr 2021;151(8):2153-2160. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC