Colostrum 500 mg Ingredients & Drug Interactions
by GNC
What is this page for?
First and foremost: checking Colostrum 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Colostrum 500 mg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Colostrum 500 mg by GNC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has one active ingredient: bovine colostrum, a nutrient-rich fluid from cows produced in the first few days after birth. The capsule also contains inactive ingredients — cellulose, gelatin, and stearic acid — which are fillers and binders that hold the formula together.
Does it work?
Moderate evidence
The evidence for bovine colostrum is mixed. It's rated possibly effective for two types of diarrhea: the kind tied to HIV/AIDS and rotaviral diarrhea (a stomach infection in children).
It's also rated possibly effective for exercise-induced respiratory infections. For necrotizing enterocolitis (a serious intestinal condition in premature infants), the evidence leans toward it being ineffective.
For other uses, we don't have effectiveness ratings on file.
How safe is it?
Well-documented data
Bovine colostrum is generally well tolerated in most adults, but there are a few caveats. If you have a milk or dairy allergy, steer clear — colostrum comes from cows and can trigger a reaction.
A small number of trial participants reported mild bloating, nausea, diarrhea, and stomach upset at rates similar to those taking a whey-based comparison. One person with HIV-related cryptosporidiosis (a parasitic infection) developed nausea and vomiting.
There's also a report of elevated liver function tests and lower red blood cell counts in some HIV patients taking it, so if you have liver or blood concerns, mention this supplement to your doctor. Safety data during breastfeeding is sparse, so talk with your provider before using it if you're nursing.
There isn't enough reliable safety information for pregnancy, so it's best to avoid it unless your doctor approves.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, always run your exact medications through our checker below before you start, and tell your doctor or pharmacist you're taking this — especially if you have HIV, liver problems, or blood disorders.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Bovine colostrum may help with certain kinds of diarrhea and exercise-related respiratory infections, though the evidence isn't rock-solid. It's generally well tolerated, but skip it if you have a dairy allergy, and talk with your doctor or pharmacist before taking it if you're pregnant, breastfeeding, or have liver or blood issues — they can weigh the potential benefit against your individual situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Colostrum 500 mg, straight from the product label.
| Brand | GNC |
|---|---|
| Barcode (UPC) | 048107121211 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2017 |
| DSLD ID | 75208 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Colostrum 500 mg by GNC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bovine Colostrum | 500 mg | -- |
Other ingredients: Cellulose, Gelatin, Stearic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Keep out of reach of children.
Contains: Milk.
Storage
Store in a cool, dry place.
General Statements
Supports natural resistance
Colostrum is full of the supporting proteins and immune factors needed to develop strong immunities.
Conforms to USP <2091> for weight. Meets USP <2040> disintegration.
FDA Statement of Identity
Dietary Supplement
General
CODE 703912 BRG
Formula
Supplies whole bovine colostrum to help support natural resistance.
Contains: Milk.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take two capsules daily. For maximum support, take as directed every day.
Formulation
No sugar, no artificial colors, no artificial flavors, sodium free, no wheat, gluten free, no corn, no soy, yeast free.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Colostrum 500 mg by GNC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Colostrum 500 mg by GNC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Bovine Colostrum
No knowninteractions
Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...
Bovine Colostrum monograph & interactionsOther (inactive) ingredients: Cellulose, Gelatin, Stearic Acid. These complete the product’s ingredient list but are not active constituents.
Colostrum 500 mg by GNC Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Colostrum 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Colostrum 500 mg, from the product label.
GNC
See all GNC products- Name
- General Nutrition Corporation
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- www.gnc.com
Colostrum 500 mg by GNC: Common Questions
Does Colostrum 500 mg by GNC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I have a milk allergy?
What side effects might I experience?
Does it really work for diarrhea?
Is it safe during pregnancy?
Can I use this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Colostrum 500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Colostrum 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Colostrum 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bovine Colostrum 8 references
- Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
- Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
- Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
- Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
- Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
- Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
- Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
- Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC