Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Reflexion Ingredients & Drug Interactions

by 4Life

Reflexion label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Reflexion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Reflexion is a dietary supplement by 4Life with 5 active ingredients. Its ingredients are commonly taken for anxiety and stress, relaxation and calm, sleep support.Based on those ingredients, 651 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine, Green Oat Herb Extract, Wild. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Reflexion by 4Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Reflexion by 4Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Reflexion by 4Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1 Gram(s)) without saying how much of each component you get.
  • “4Life Tri-Factor Formula” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.

Reflexion contains 5 active ingredients. L-theanine is an amino acid that may support focus and calm.

Green oat herb extract comes from wild oats and provides fiber and nutrients. The product also includes NanoFactor, 4Life Tri-Factor Formula, and UltraFactor — proprietary blends and branded ingredients designed to support brain function.

The capsule itself is made from vegetable material, with magnesium stearate and silicon dioxide as inactive binders and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cope with stress, promote relaxation and focus.
  • We looked for evidence on: Anxiety, Stress, Generalized anxiety disorder (GAD), Cognitive function, Attention deficit-hyperactivity disorder (ADHD), Nervousness — and 2 related terms.
  • The strongest evidence on file: Theanine is rated "Possibly Effective" for Cognitive function (Natural Medicines).
  • Also on file: Oats is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Cognitive function.
  • Also on file: Theanine is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Attention deficit-hyperactivity disorder (ADHD), Stress.

L-theanine is possibly effective for cognitive function, though evidence for age-related cognitive decline, Alzheimer disease, anxiety, OCD, and cancer is insufficient. Green oat herb extract is likely effective for cholesterol balance (dyslipidemia) and heart health (coronary heart disease).

The effectiveness of the other proprietary ingredients in this product is not established in the data we hold.

The evidence, ingredient by ingredient Theanine Oats

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-theanine is generally well tolerated for short-term use in healthy adults, but long-term safety hasn't been well studied. Reported side effects include headaches, drowsiness, increased sleep duration, and vivid dreams.

One case of a facial tic was reported in a child taking 400 mg daily, though the tic resolved when theanine was stopped — the link was unclear. Green oat herb extract is well tolerated when taken orally; fiber-related side effects like bloating, gas, abdominal distension, and unpleasant taste may occur, especially when doses are increased quickly.

These usually fade with continued use. There isn't enough safety data to recommend L-theanine during pregnancy or breastfeeding.

Green oat food is generally considered safe in pregnancy and while breastfeeding, though concentrated oat supplements are less studied.

Side effects, ingredient by ingredient Theanine Oats

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Oats, Theanine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 651 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Reflexion, check your medications against these drug types: blood pressure drugs (antihypertensives) — theanine may lower blood pressure further; diabetes drugs and insulin — oat extract may increase low blood sugar risk; and sedating drugs (CNS depressants) — minor additive effects are possible. If you take any of these, confirm with your doctor or pharmacist that this product is safe for you.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Reflexion may appeal to people looking to support focus and cognitive performance. If you take blood pressure medications, diabetes drugs, insulin, or sedating medications, you should check with your doctor or pharmacist before starting this product — the oat and theanine content could affect how those drugs work.

Talk it over with your own healthcare provider to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reflexion, straight from the product label.

Brand 4Life
Barcode (UPC) 22005
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 301044
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reflexion by 4Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
22005
IngredientAmount% DV
Proprietary Blend1 Gram(s)--
L-Theanine0 NP--
NanoFactor0 NP--
4Life Tri-Factor Formula100 mg--
OvoFactor0 NP--
UltraFactor0 NP--
Green Oat Herb Extract, Wild0 NP--

Other ingredients: Vegetable Capsule, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

4Life Transfer Factor Reflexion helps you cope with the daily stresses of life! It promotes relaxation, immune system health, cognitive function, and the ability to focus during times of occasional stress.

Made in the USA with quality ingredients from around the world

Mood & stress

Brand IP Statement(s)

4Life Transfer Factor is protected by US Patents 6,468,534 and 6,866,868 with other patents pending. Copyright 2021 4Life Trademarks, LLC

Seals/Symbols

Certified 4Life Transfer Factor

General Statements

A product of 4Life

Precautions

Keep out of reach of children.

Contains ingredients from milk and egg.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Targeted Transfer Factor

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take two (2) capsules daily with 8 oz of fluid.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Reflexion by 4Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Reflexion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Reflexion by 4Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1 Gram(s) per serving

4Life Tri-Factor Formula

100 mg per serving
  • › NanoFactor
  • › OvoFactor
  • › UltraFactor

Other (inactive) ingredients: Vegetable Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reflexion by 4Life Drug Interactions

Want to check YOUR meds against Reflexion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
651Drugs
258 Moderate 393 Minor

Ingredients driving the most interactions

L-Theanine 565
Green Oat Herb Extract, Wild 86

Individual Drug Interactions

The ingredients in Reflexion interact with 651 drugs. Click any drug to see the details.

2 of the 5 ingredients in Reflexion interact with drugs. Each result below shows which ingredient is responsible. L-Theanine Green Oat Herb Extract, Wild

Each ingredient & the kinds of drugs it affects

For each ingredient in Reflexion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Theanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C
L-Theanine full monograph & interactions

Green Oat Herb Extract, Wild2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
Green Oat Herb Extract, Wild full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Reflexion, from the product label.

4Life

Name
BioMedical Research Laboratories, LLC
Street Address
9850 South 300 West
City
Sandy
State
UT
ZipCode
84070
Phone Number
888-454-3374
Web Address
4Life.com
Pharmacist Counseling Corner

Reflexion by 4Life: Common Questions

Does Reflexion by 4Life interact with any medications?
Yes. Based on its ingredients, Reflexion has a known interaction with 651 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reflexion contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Reflexion actually help my memory and thinking?
L-theanine is possibly effective for cognitive function, but evidence for memory, age-related decline, or Alzheimer disease is still insufficient. The oat extract is likely effective for heart and cholesterol health, not cognition. Results vary by person, and you should discuss realistic expectations with your pharmacist.
Is it safe to take Reflexion if I'm pregnant or breastfeeding?
There isn't enough safety data for L-theanine during pregnancy or breastfeeding, so it's best to avoid it. Green oat as food is generally considered safe during pregnancy and breastfeeding, but concentrated supplement forms are less studied. Talk with your doctor or pharmacist about whether this product is right for you.
What side effects might I experience from L-theanine?
Common side effects include headaches, drowsiness, longer sleep, and vivid dreams. Gas, bloating, and abdominal distension can occur from the oat fiber, especially at first — these usually ease with time. If you experience new or unusual symptoms, stop and talk with your pharmacist.
I take blood pressure medication. Can I still take Reflexion?
L-theanine in this product may lower blood pressure and could intensify your medication's effect. You should check with your doctor or pharmacist before starting — they can monitor you or adjust your dose if needed to keep you safe.
How does the oat extract in Reflexion affect my diabetes medications?
Oats can lower blood sugar and may reduce the insulin dose you need. If you take diabetes drugs or insulin, combining this product could increase your risk of low blood sugar (hypoglycemia). Confirm with your doctor or pharmacist that it's safe before you start.
Does Reflexion have any fillers or unnecessary ingredients?
The capsule contains vegetable material, magnesium stearate (a binder), and silicon dioxide (a flow agent) — standard inactive ingredients used to form and protect the supplement. There are no unnecessary additives beyond what's needed to deliver the active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reflexion is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reflexion label
Go deeper

The Full Monographs Behind Reflexion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theanine

Interacts with 565 drugs

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...

Read the full Theanine monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph →
Sources

Sources & How We Checked

Reflexion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theanine 6 references
  1. Yokogoshi H, Kobayashi M. Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. Life Sci 1998;62:1065-8.
  2. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., and Scholey, A. B. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol.Psychol. 2008;77(2):113-122. PubMed
  3. Yokogoshi, H., Kato, Y., Sagesaka, Y. M., Takihara-Matsuura, T., Kakuda, T., and Takeuchi, N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci.Biotechnol.Biochem. 1995;59(4):615-618. PubMed
  4. Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-
  5. Hidese S, Ota M, Wakabayashi C, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr 2017;29(2):72-9.
  6. Tsuchiya T, Honda H, Oikawa M, et al. Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients. Int J Clin Oncol 2016;21(6):1085-90. PubMed

See these in context on the Theanine monograph →

Oats 13 references
  1. Cooper SG, Tracey EJ. Small-bowel obstruction caused by oat-bran bezoar. N Engl J Med 1989;320:1148-9. DOI
  2. Pick ME, Hawrysh ZJ, Gee MI, et al. Oat bran concentrate bread products improve long-term control of diabetes: a pilot study. J Am Diet Assoc 1996;96:1254-61. PubMed
  3. Braaten JT, Scott FW, Wood PJ, et al. High beta-glucan oat bran and oat gum reduce postprandial blood glucose and insulin in subjects with and without type 2 diabetes. Diabet Med 1994;11:312-8.
  4. Rosario PG, Gerst PH, Prakash K, Albu E. Dentureless distention: oat bran bezoars cause obstruction. J Am Geriatr Soc 1990;38:608. PubMed
  5. Food and Drug Administration. Food labeling: health claims: oats and coronary heart disease. Fed Regist 1996;61:296-313.
  6. Foulke J. FDA Allows Whole Oat Foods To Make Health Claim on Reducing the Risk of Heart Disease. FDA Talk Paper. 1997. Available at: http://www.fda.gov/bbs/topics/ANSWERS/ANS00782.html.
  7. Chandalia M, Garg A, Lutjohann D, et al. Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. N Engl J Med 2000;342:1392-8. PubMed
  8. Lembo A, Camilleri M. Chronic constipation. N Engl J Med 2003;349:1360-8. . PubMed
  9. De Paz Arranz S, Perez Montero A, Remon LZ, Molero MI. Allergic contact urticaria to oatmeal. Allergy 2002;57:1215. . PubMed
  10. Delgado G, Kleber ME, Krämer BK, et al. Dietary intervention with oatmeal in patients with uncontrolled type 2 diabetes mellitus - A crossover study. Exp Clin Endocrinol Diabetes. 2019;127(9):623-629. PubMed
  11. Sobhan M, Hojati M, Vafaie SY, Ahmadimoghaddam D, Mohammadi Y, Mehrpooya M. The efficacy of colloidal oatmeal cream 1% as add-on therapy in the management of chronic irritant hand eczema: A double-blind study. Clin Cosmet Investig Dermatol. 2020;13:241-25
  12. Hou Q, Li Y, Li L, Cheng G, Sun X, Li S, Tian H. The metabolic effects of oats intake in patients with type 2 diabetes: A systematic review and meta-analysis. Nutrients. 2015;7(12):10369-87. PubMed
  13. González-Afonso M, Cañas JA, Sastre B, et al. A Case of Anaphylaxis After Ingestion of Oats: Research Into New Allergens. J Investig Allergol Clin Immunol 2022;32(6):506-508. PubMed

See these in context on the Oats monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team