No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Colostrum ImmunDefense Ingredients & Drug Interactions

by Wonder Laboratories

Capsule Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Colostrum ImmunDefense is a dietary supplement by Wonder Laboratories with 3 active ingredients. Its ingredients are commonly taken for iron deficiency and anemia support, immune support, gut health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Colostrum ImmunDefense by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients. Lactoferrin is a protein naturally found in milk and other body fluids; it plays a role in immune function and iron transport.

Lysozyme and colostrum (the nutrient-rich fluid produced in the first days after birth) are the other two active ingredients, each with their own roles in immune support. The capsule also contains inactive ingredients: gelatin, vegetable cellulose, silica, and vegetable magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lactoferrin's overall clinical evidence instead.

Moderate

Some clinical evidence supports Lactoferrin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Natural Medicines).
  • On file: Sepsis — rated "Possibly Effective" (Natural Medicines).

The evidence we hold covers lactoferrin only. It's possibly effective for sepsis (a life-threatening blood infection) and pregnancy-related iron deficiency.

For fetal and premature infant mortality and necrotizing enterocolitis (a serious intestinal condition in newborns), the data suggests it's likely ineffective. We don't have effectiveness ratings for lysozyme or colostrum in our data.

The evidence, ingredient by ingredient Lactoferrin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactoferrin is generally well tolerated at typical oral doses, though long-term safety data are limited. At higher doses (7.2 grams daily), constipation, diarrhea, loss of appetite, and fatigue have been reported.

It carries a Likely Safe or Possibly Safe rating in pregnancy, though safety isn't fully established — medical supervision is advised. While lactoferrin occurs naturally in breast milk, the safety of supplements while breastfeeding hasn't been well studied.

We have no adverse-effect data on file for lysozyme or colostrum.

Side effects, ingredient by ingredient Lactoferrin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This product may appeal to people looking for immune support from whole-food sources. If you're pregnant or breastfeeding, talk with your pharmacist or doctor first — the safety data for supplements here aren't complete, even though the ingredients appear in your body naturally.

Anyone taking medications should check them against this product before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colostrum ImmunDefense, straight from the product label.

Brand Wonder Laboratories
Barcode (UPC) 099528234127
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 215216
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colostrum ImmunDefense by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
UPC/BARCODE
099528234127
IngredientAmount% DV
Lactoferrin25 mg--
Lysozyme5 mg--
Colostrum250 mg--

Other ingredients: Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 to 4 capsules before bedtime.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Do not take this product if you are sensitive to dairy products.

Contains milk, egg & soy ingredients.

Formulation

Manufactured in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Free of synthetic hormones, pesticides and antibiotics.

Nutritional support for a healthy immune system

Gluten free

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Brand IP Statement(s)

ColostruMune is a trademark of Sterling Technologies.

General Statements

Reorder # 2342

Formula 234

Made in USA

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Colostrum Lactoferrin Lysozyme

Ko Kosher Service Dairy

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Ko Kosher Service Dairy

See for yourself

Colostrum ImmunDefense by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Colostrum ImmunDefense by Wonder Laboratories

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactoferrin

No known
interactions
25 mg per serving

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is...

Lactoferrin monograph & interactions

Lysozyme

5 mg per serving

Colostrum

250 mg per serving Form: IgG

Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colostrum ImmunDefense by Wonder Laboratories Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Colostrum ImmunDefense. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Colostrum ImmunDefense, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Colostrum ImmunDefense by Wonder Laboratories: Common Questions

Does Colostrum ImmunDefense by Wonder Laboratories interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Colostrum ImmunDefense. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Colostrum ImmunDefense contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is lactoferrin safe to take every day?
At typical doses, yes — it's generally well tolerated. But long-term safety data are limited, so it's worth talking with your pharmacist about how long you plan to take it. Higher doses (7.2 grams daily) do increase the risk of side effects like constipation and diarrhea.
Can I take this if I'm pregnant?
Lactoferrin itself has a Likely Safe or Possibly Safe rating in pregnancy, but safety isn't fully established. You should only use it under medical supervision. Talk with your doctor or pharmacist before starting — they know your full health picture and can help you decide.
What side effects might I notice?
At typical doses, lactoferrin usually doesn't cause problems. If you take a higher dose, you might notice constipation, diarrhea, loss of appetite, or fatigue. Stomach discomfort like nausea or epigastric pain is also possible but less common than with other iron supplements.
Is colostrum the same as what's in breast milk?
Colostrum is the nutrient-rich fluid produced in the first days after birth — it's one part of what mothers produce. This supplement contains bovine (cow) colostrum, not human colostrum, and is processed into a capsule form.
Does this product have fillers in it?
Yes. Beyond the three active ingredients, the capsule contains gelatin, vegetable cellulose, silica, and vegetable magnesium stearate — these are the binders and capsule material.
What is lysozyme?
Lysozyme is an enzyme found naturally in many body fluids, including tears, saliva, and mucus. It's thought to play a role in immune defense. We don't have detailed effectiveness data on file for it as a supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Colostrum ImmunDefense is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colostrum ImmunDefense label
Go deeper

The Full Monographs Behind Colostrum ImmunDefense’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Colostrum ImmunDefense's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactoferrin 6 references
  1. Food and Drug Administration, CFSAN/Office of Food Additive Safety. Agency Response Letter GRAS Notice No. GRN 000130. 2003. Available at: http://www.cfsan.fda.gov/~rdb/opa-g130.html (Accessed 29 June 2005).
  2. Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. PubMed
  3. Abu Hashim H, Foda O, Ghayaty E. Lactoferrin or ferrous salts for iron deficiency anemia in pregnancy: A meta-analysis of randomized trials. Eur J Obstet Gynecol Reprod Biol. 2017;219:45-52. PubMed
  4. Tarnow-Mordi WO, Abdel-Latif ME, Martin A, et al. The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 Jun PubMed
  5. ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet. 2019 Feb 2;393(10170):423-433. doi: 10.1016/S0140-6736(18)32221-9.
  6. Lepanto MS, Rosa L, Cutone A, Conte MP, Paesano R, Valenti P. Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: An interventional study. Front Immunol. 2018 Sep 21;9:2123. PubMed

See these in context on the Lactoferrin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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