CompleteGest Ingredients & Drug Interactions
by Nature's Way
What is this page for?
First and foremost: checking CompleteGest against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CompleteGest is a dietary supplement by Nature's Way with 7 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of CompleteGest by Nature's Way
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
CompleteGest contains 7 active digestive enzymes designed to break down different parts of food. Protease breaks down proteins, lactase helps digest milk sugar (lactose), lipase handles fats, and cellulase works on plant fiber.
The blend also includes amylase for starches, sucrase for table sugar, and phytase — enzymes that work together to support your digestive process. The capsule itself is plant-derived, and the formula includes cellulose and magnesium stearate as inactive ingredients to bind and fill out the capsule.
Does it work?
Strong evidence
The evidence is mixed. Lactase is rated effective for lactose intolerance — if you have trouble digesting milk products, this ingredient does what it's supposed to do.
For the other enzymes in the blend, the data we hold doesn't establish effectiveness yet. Lipase, phytase, and the other digestive enzymes haven't been rated as proven effective for their intended uses based on the evidence available to us.
How safe is it?
Well-documented data
These enzymes are generally well tolerated when taken as directed. That said, digestive upset is possible, and rarely, people have reported allergic reactions to protease or lactase — usually in occupational settings with powder exposure, but allergy is on the table.
If you have a serious digestive condition, check with your doctor before starting, because the safety data for people with inflammatory bowel disease or similar issues is limited. During pregnancy, the safety data aren't solid enough to say it's okay without medical advice — talk to your doctor first.
Breastfeeding safety also hasn't been well studied, so ask your healthcare provider before using regularly.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we were unable to check Amylase, Cellulase, and Sucrase, so if you take any medications, it's worth a quick confirmation with your doctor or pharmacist before adding this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
CompleteGest is a straightforward digestive enzyme blend; if you have lactose intolerance, the lactase ingredient is proven to help. For general digestive support, the evidence isn't established yet, so results may vary.
Because three of the seven enzymes haven't been checked for drug interactions and pregnancy/breastfeeding data are limited across the board, talk with your doctor or pharmacist before starting — especially if you're pregnant, breastfeeding, or have a digestive condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CompleteGest, straight from the product label.
| Brand | Nature's Way |
|---|---|
| Barcode (UPC) | 763948042395 |
| Net contents | 90 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2021 |
| DSLD ID | 249507 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CompleteGest by Nature's Way, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Vegetarian Enzymes | 281 mg | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Lipase I, II | 0 NP | -- |
| Sucrase | 0 NP | -- |
| Phytase | 0 NP | -- |
Other ingredients: plant-derived Capsule, Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Contains no dairy, or artificial colors, flavors, or preservatives.
Vegan
Helps digest foods
Mealtime Enzyme Formula
Precautions
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
Caution: If you are pregnant, nursing, have diabetes, or if you are taking any medication, consult a healthcare professional before use.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.
Brand IP Statement(s)
2021 Distributed by Nature's Way Brands, LLC
Seals/Symbols
Quality Global Sourcing Bottled & Tested in the USA
FDA Disclaimer Statement
This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Nature's Way since 1969
Formula
Vegetarian Enzymes
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendation: Adults take 1 capsule with meals up to six times daily.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CompleteGest by Nature's Way label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CompleteGest by Nature's Way
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vegetarian Enzymes
- › Amylase
- › Protease
- › Lactase
- › Cellulase
- › Lipase I, II
- › Sucrase
- › Phytase
Other (inactive) ingredients: Plant-derived Capsule, Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
CompleteGest by Nature's Way Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in CompleteGest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for CompleteGest, from the product label.
Nature's Way
See all Nature's Way products- Name
- Nature's Way Brands, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 1-800-962-8873
- Web Address
- naturesway.com
CompleteGest by Nature's Way: Common Questions
Does CompleteGest by Nature's Way interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does this help with lactose intolerance?
Can I take this if I'm pregnant?
Are there any side effects?
Is this safe while breastfeeding?
Will this work for bloating or gas?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CompleteGest is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CompleteGest’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph →Sources & How We Checked
CompleteGest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC