Constipation Formula Mint Flavor Ingredients & Drug Interactions
by TerraVita
What is this page for?
First and foremost: checking Constipation Formula Mint Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Constipation Formula Mint Flavor is a dietary supplement by TerraVita with 3 active ingredients. Its ingredients are commonly taken for high cholesterol, indigestion and heartburn, constipation and bloating.Based on those ingredients, 790 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Boldo Glycerite Liquid Extract, Artichoke Leaf Glycerite Liquid Extract, Black Radish Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Constipation Formula Mint Flavor by TerraVita
Ask about any prescription or over-the-counter medication and we check it for interactions with Constipation Formula Mint Flavor by TerraVita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Constipation Formula Mint Flavor by TerraVita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 3 active ingredients in liquid form: artichoke leaf glycerite liquid extract, boldo glycerite liquid extract, and black radish glycerite liquid extract. The formula also includes glycerin and mint flavor as inactive ingredients.
Each ingredient is meant to support digestive and biliary function, though the evidence for some uses is still limited.
Does it work?
Moderate evidence
Artichoke leaf extract is possibly effective for high cholesterol (hyperlipidemia) and indigestion (dyspepsia). For boldo and black radish, we hold insufficient evidence to rate their effectiveness for the conditions they're traditionally used for — including gallbladder disease, kidney stones, and diabetes — so we can't tell you whether they work based on the data we have.
If constipation relief is your goal, the effectiveness of this specific blend isn't detailed in our data.
How safe is it?
Well-documented data
Artichoke is generally well tolerated, but the most common side effects are abdominal pain, diarrhea, flatulence, hunger, and nausea. Rarely, people sensitive to artichoke inulin have had anaphylaxis.
If you're allergic to ragweed, chrysanthemums, or other plants in the Asteraceae family, you're at higher risk of reacting to artichoke. Boldo carries more caution: it contains ascaridole, a liver toxin, and cases of elevated liver enzymes and jaundice have been reported.
The safety data advises against boldo in pregnancy because it may stimulate the uterus, and there isn't enough information to know if it's safe while breastfeeding. For artichoke, there also isn't enough data to know if it's safe in pregnancy or while breastfeeding — talk with your pharmacist or doctor about whether to use it during these times.
Black radish is generally safe in normal food amounts, though large amounts may irritate your stomach. A case of allergic reaction (throat tightness and hives) to radish has been reported.
Meds to double-check
Moderate interaction found
Before taking this product, double-check your medications against these types: blood thinners and antiplatelet drugs (Moderate severity), blood pressure medications, diabetes drugs, and any drugs that affect your liver or are processed through your liver's CYP2C19 or CYP2B6 pathways (all Moderate). Also check if you take lithium or tacrolimus — boldo may raise lithium levels or lower tacrolimus levels.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This formula combines three plant extracts with multiple documented interactions, particularly with blood thinners, diabetes and blood pressure medications, and liver-affecting drugs. If you take any prescription medications, especially warfarin, lithium, tacrolimus, or drugs that affect your liver, check them against this product before starting.
Talk with your pharmacist to make sure it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Constipation Formula Mint Flavor, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Constipation Formula Mint Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 0.13 mL | -- |
| Artichoke Leaf Glycerite Liquid Extract | 0 NP | -- |
| Boldo Glycerite Liquid Extract | 0 NP | -- |
| Black Radish Glycerite Liquid Extract | 0 NP | -- |
Other ingredients: Glycerin, Mint Flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Formula
Glycerite liquid extract (1:5)
Formulation
Alcohol free
Suggested/Recommended/Usage/Directions
Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.
Precautions
Keep away from children.
Do not use if safety seal around cap is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Constipation Formula Mint Flavor by TerraVita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Constipation Formula Mint Flavor by TerraVita
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Glycerin, Mint Flavor. These complete the product’s ingredient list but are not active constituents.
Constipation Formula Mint Flavor by TerraVita Drug Interactions
HelloPharmacist Interaction Report
TerraVita's Constipation Formula Mint Flavor contains three active ingredients, and together they interact with a significant number of medications.
The most serious concern is boldo leaf extract, which can damage your liver — especially risky if you're also taking other drugs that stress the liver (hepatotoxic drugs). Boldo also theoretically increases bleeding risk with blood thinners (anticoagulant and antiplatelet drugs) like warfarin, and may raise lithium levels to harmful amounts.
Read the full breakdown — every affected drug type, severity by severity
Artichoke leaf extract may lower your blood pressure if you're on blood pressure medications (antihypertensive drugs), and could raise low blood sugar risk if you take diabetes drugs (antidiabetes drugs). It may also slow how your liver clears certain medications metabolized by CYP2C19 or CYP2B6, potentially raising their levels — though this hasn't been confirmed in humans.
Black radish extract similarly may increase the risk of low blood sugar with diabetes medications.
Altogether, these interactions span 773 individual medications. Before you start this product, run all your current prescriptions through the interaction checker below, especially if you take blood thinners, diabetes drugs, blood pressure pills, lithium, or tacrolimus (an immunosuppressant).
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Constipation Formula Mint Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Constipation Formula Mint Flavor interact with 790 drugs. Click any drug to see the details.
3 of the 3 ingredients in Constipation Formula Mint Flavor interact with drugs. Each result below shows which ingredient is responsible. Boldo Glycerite Liquid Extract Artichoke Leaf Glycerite Liquid Extract Black Radish Glycerite Liquid Extract
Acetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Constipation Formula Mint Flavor — through 1 ingredient. Tap an ingredient for the detail:
Boldo Glycerite Liquid ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Read the full Boldo Glycerite Liquid Extract + Acetaminophen, Meperidine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Constipation Formula Mint Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Boldo Glycerite Liquid Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, taking boldo with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
Animal and in vitro research shows that boldine, a constituent of boldo, has antiplatelet activity. In one case report, an adult taking a combination of boldo and fenugreek with warfarin experienced an increase in international normalized ratio (INR); however, it is unclear if this effect was due to boldo, fenugreek, the combination, or another factor.
Hepatotoxic Drugs
Theoretically, taking boldo with hepatotoxic drugs might increase the risk of hepatic injury and disease.
Boldo leaf contains ascaridole, a known liver toxin. Many cases of hepatotoxicity, including elevated liver transaminase levels and jaundice, have been reported in patients taking boldo.
Lithium
Theoretically, taking boldo with lithium might increase the levels and clinical effects of lithium.
Boldo is believed to have diuretic effects. Theoretically, these diuretic effects might reduce the excretion of lithium. The dose of lithium might need to be decreased.
Tacrolimus (Prograf)
Taking boldo with tacrolimus may decrease the levels and clinical effects of tacrolimus, potentially increasing the risk of transplant rejection.
In one case report, a patient with a long-term history of stable tacrolimus levels developed subtherapeutic levels after taking boldo 300 mg twice daily orally for several weeks. Tacrolimus levels returned to normal after discontinuing boldo. However, the mechanism of this interaction is unclear.
Warfarin (Coumadin)
A combination of boldo and fenugreek was thought to be associated with an increased international normalized ratio (INR) in a female on warfarin. It is not clear if boldo, fenugreek, or the combination played a role in this interaction. Therefore, boldo may have additive effects with warfarin.
Artichoke Leaf Glycerite Liquid Extract
Antidiabetes Drugs
Theoretically, artichoke leaf extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
A meta-analysis of small clinical studies shows that taking artichoke leaf extract for 8-12 weeks can modestly reduce fasting plasma glucose when compared with placebo.
Antihypertensive Drugs
Theoretically, artichoke leaf extract may increase the risk of hypotension when taken with antihypertensive drugs.
A meta-analysis of small clinical studies in patients with hypertension shows that taking artichoke can reduce systolic blood pressure by around 3 mmHg and diastolic blood pressure by around 2 mmHg when compared with placebo.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2B6.
In vitro research shows that artichoke leaf extract inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2C19.
In vitro research shows that artichoke leaf extract inhibits CYP2C19 activity. However, this interaction has not been reported in humans.
Black Radish Glycerite Liquid Extract
Antidiabetes Drugs
Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that radish extract, juice, and sprouts can reduce glucose levels. Animal research also shows that radish root juice 300 mg/kg reduces fasting and postprandial blood glucose in a rat model of diabetes, with effects similar to glibenclamide.
Brand information
Manufacturer and brand details for Constipation Formula Mint Flavor, from the product label.
TerraVita
See all TerraVita products- Name
- ZooScape LLC
- Phone Number
- 844-449-0444
- Web Address
- www.ZooScape.com
Constipation Formula Mint Flavor by TerraVita: Common Questions
Does Constipation Formula Mint Flavor by TerraVita interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take during pregnancy?
Is this safe while breastfeeding?
What are the most common side effects?
Does this product actually work for constipation?
What if I'm allergic to ragweed or similar plants?
Can boldo damage my liver?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Constipation Formula Mint Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Constipation Formula Mint Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Artichoke
Interacts with 363 drugsArtichoke leaf extract is a generally well-tolerated supplement that may have a mild cholesterol-lowering effect and is often used for indigestion, though the evidence is modest. It is not a...
Read the full Artichoke monograph → Herb & supplement monographBoldo
Interacts with 482 drugsBoldo is a South American shrub whose leaves are traditionally used for digestive and gallbladder complaints, but good human evidence is very limited. The leaves and oil contain ascaridole,...
Read the full Boldo monograph → Herb & supplement monographRadish
Interacts with 86 drugsRadish is a common edible root vegetable that is nutritious and generally safe to eat as food. Some people use radish (especially black radish) and its extracts for digestion and liver suppo...
Read the full Radish monograph →Sources & How We Checked
Constipation Formula Mint Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Artichoke 16 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Walker AF, Middleton RW, Petrowicz O. Artichoke leaf extract reduces symptoms of irritable bowel syndrome in a post-marketing surveillance study. Phytother Res 2001;15:58-61. PubMed
- Pittler MH, White AR, Stevinson C, Ernst E. Effectiveness of artichoke extract in preventing alcohol-induced hangovers: a randomized controlled trial. CMAJ 2003;169:1269-73.
- Romano, C., Ferrara, A., and Falagiani, P. A case of allergy to globe artichoke and other clinical cases of rare food allergy. J Investig.Allergol.Clin Immunol. 2000;10(2):102-104.
- Miralles, J. C., Garcia-Sells, J., Bartolome, B., and Negro, J. M. Occupational rhinitis and bronchial asthma due to artichoke (Cynara scolymus). Ann Allergy Asthma Immunol. 2003;91(1):92-95. PubMed
- Franck, P., Moneret-Vautrin, D. A., Morisset, M., Kanny, G., Megret-Gabeaux, M. L., and Olivier, J. L. Anaphylactic reaction to inulin: first identification of specific IgEs to an inulin protein compound. Int Arch Allergy Immunol 2005;136(2):155-158. PubMed
- Meding, B. Allergic contact dermatitis from artichoke, Cynara scolymus. Contact Dermatitis 1983;9(4):314.
- Quirce, S., Tabar, A. I., Olaguibel, J. M., and Cuevas, M. Occupational contact urticaria syndrome caused by globe artichoke (Cynara scolymus). J Allergy Clin Immunol. 1996;97(2):710-711. PubMed
- Held C. Von der 1. Deutsche-Ungarischen Phytopharmakon-Konferenz, Budapest, 20. November 1991. Z Klin Med 1992;47:92-93.
- Barrat E, Zaïr Y, Ogier N, et al. A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial. Int J Food Sci Nutr. 2013;64(7):882-9. PubMed
- Huber R, Müller M, Naumann J, Schenk T, Lüdtke R. Artichoke leave extract for chronic hepatitis C - a pilot study. Phytomedicine. 2009 Sep;16(9):801-4. PubMed
- Caputo F, Barranco R, Bonsignore A, Fraternali Orcioni G, Ventura F. A rare case of fatal bowel obstruction secondary to a colonic bezoar. Am J Forensic Med Pathol. 2018;39(1):38-40. PubMed
- Elsebai MF, Abass K, Hakkola J, Atawia AR, Farag MA. The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials. Food Funct. 2016;7(7):3006-16. PubMed
- Moradi M, Sohrabi G, Golbidi M, et al. Effects of artichoke on blood pressure: a systematic review and meta-analysis. Complement Ther Med 2021;57:102668. PubMed
- Jalili C, Moradi S, Babaei A, et al. Effects of Cynara scolymus L. on glycemic indices: a systematic review and meta-analysis of randomized clinical trials. Complement Ther Med 2020;52:102496. PubMed
- Gallo R, Oddenino G, Trave I, Gasparini G, Guadagno A, Parodi A. Contact sensitivity to sesquiterpene lactone mix and artichoke in a patient with severe recurrent dermatitis: A puzzling case. Contact Dermatitis 2023;88(2):156-158. PubMed
Boldo 10 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Piscaglia F, Leoni S, Venturi A, et al. Caution in the use of boldo in herbal laxatives: a case of hepatotoxicity. Scand J Gastroenterol 2005;40:236-9. PubMed
- Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
- Teng, C. M., Hsueh, C. M., Chang, Y. L., Ko, F. N., Lee, S. S., and Liu, K. C. Antiplatelet effects of some aporphine and phenanthrene alkaloids in rabbits and man. J Pharm Pharmacol 1997;49(7):706-711. PubMed
- Carbajal R, Yisfalem A, Pradhan N, et al. Case report: Boldo (Peumus boldus) and tacrolimus interaction in a renal transplant patient. Transplant Proc 2014;46(7):2400-2. PubMed
- Almeida ER, Melo AM, Xavier H. Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats. Phytother Res 2000;14(2):99-102. DOI
- Ribeiro RJ, Silvestre C, Duarte C. Hidden risks of alternative medicines: a case of boldo-induced hepatotoxicity. J Diet Suppl 2017;14(2):186-90. PubMed
- Oliveira Sá A, Pimentel T, Oliveira N. Boldo-Induced Hepatotoxicity: A Case of Unexplained Jaundice. Eur J Case Rep Intern Med 2020;7(12):002116. PubMed
- Valdes R, Feuereisen A, Bellinghausen M. Allergic Contact Dermatitis to Boldo. Dermatitis 2021;32(2):e31-e32. PubMed
Radish 5 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Damiani E, Aloia AM, Priore MG, Nardulli S, Ferrannini A. Generalized urticaria after ingestion of Raphanus sativus. Ann Allergy Asthma Immunol. 2011 Feb;106(2):168. PubMed
- Evans M, Paterson E, Barnes DM. An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. BMC Complement Altern Med. 2014 Dec 9;14:475. PubMed
- Banihani SA. Radish (Raphanus sativus) and diabetes. Nutrients. 2017;9(9). pii: E1014. PubMed
- Shukla S, Chatterji S, Mehta S, Rai PK, Singh RK, Yadav DK, Watal G. Antidiabetic effect of Raphanus sativus root juice. Pharm Biol. 2011 Jan;49(1):32-7.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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