Copper Citrate 2 mg Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Copper Citrate 2 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Copper Citrate 2 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for preventing or treating copper deficiency, supporting red blood cell formation, bone and connective tissue health.Based on those ingredients, 31 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Copper Citrate 2 mg by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Copper Citrate 2 mg by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Copper Citrate 2 mg by Solaray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: copper (as citrate), at 2 mg per capsule. Copper is an essential mineral your body needs for healthy bones, nerves, and immune function.
The capsule also contains several inactive ingredients — rice concentrate, cellulose, dandelion, watercress, horsetail, yellow dock, rice bran extract, and silica — which are fillers, binders, and plant-based additions that don't affect the copper itself.
Does it work?
Strong evidence
Copper supplements are likely effective for treating copper deficiency, which can occur with certain conditions or diets. For Alzheimer disease, the evidence currently suggests it's possibly ineffective.
For acne, brain tumors, and chemotherapy-related anemia, the evidence we hold isn't reliable enough to rate whether it works.
How safe is it?
Well-documented data
Copper from food and standard-dose supplements is well tolerated in most people. However, excess copper can be toxic, so stick to recommended amounts — don't take high-dose supplements without medical guidance.
Contact dermatitis from copper is rare but has been reported. In studies of children, a small number developed superficial burns after topical copper sulfate, though oral supplements carry a different risk profile.
People with diabetes may naturally have higher blood copper levels than others, though it's unclear whether elevated copper contributes to diabetes or worsens it.
Meds to double-check
Moderate interaction found
Before you take this, double-check penicillamine (Moderate interaction — copper reduces how much gets absorbed) and oral contraceptive birth control pills (Minor interaction — copper levels may rise). If you take penicillamine, separate the doses by at least 2 hours.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This 2 mg copper supplement is a reasonable choice if you're correcting a copper deficiency. If you take penicillamine or oral contraceptives, check with your pharmacist first — spacing and monitoring may be needed.
Anyone with diabetes or a history of copper sensitivity should talk to their doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Copper Citrate 2 mg, straight from the product label.
| Brand | Solaray |
|---|---|
| Barcode (UPC) | 076280045963 |
| Net contents | 60 VegCap(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 338294 |
| Product type | Mineral |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Copper Citrate 2 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Copper | 2 mg | 222% |
Other ingredients: whole Rice concentrate, Cellulose, Dandelion, Watercress, Horsetail, Yellow Dock, Rice Bran Extract, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Solaray Est. 1973 A brighter way 1973
Formula
Essential trace mineral
Discussion: Copper Citrate is a specially chelated form of copper using citric acid. Minerals bonded with citric acid are specifically formulated for people with insufficient stomach acid and are intended to improve mineral bioavailability.
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Lab Verified Vegan
Formulation
Vegan
General Statements
Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.
100% PCR bottles
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product. Directions: Use only as directed.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Take 1 VegCap daily with a meal or glass of water.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Copper Citrate 2 mg by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Copper Citrate 2 mg by Solaray
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 VegCap(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Copper
Interacts with31 drugs
Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...
Copper monograph & interactionsOther (inactive) ingredients: Whole Rice concentrate, Cellulose, Dandelion, Watercress, Horsetail, Yellow Dock, Rice Bran Extract, Silica. These complete the product’s ingredient list but are not active constituents.
Copper Citrate 2 mg by Solaray Drug Interactions
HelloPharmacist Interaction Report
Copper Citrate by Solaray can interact with a couple of medication categories.
The most serious is penicillamine (Cuprimine, Depen), used to treat heavy metal poisoning and rheumatoid arthritis — copper binds to penicillamine and reduces how much of it your body absorbs, which may weaken its effect. Space your copper dose at least 2 hours apart from penicillamine.
Read the full breakdown — every affected drug type, severity by severity
If you take oral contraceptives (birth control pills), copper levels in your blood may rise. Studies show that chronic use of birth control can increase serum copper by an average of 57 mcg/dL, often pushing levels above the normal range.
This is rated Minor severity, but it's worth keeping an eye on.
Altogether, these interactions span 31 individual medications. Run your exact prescriptions through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Copper Citrate 2 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Copper Citrate 2 mg interact with 31 drugs. Click any drug to see the details.
1 of the 1 ingredient in Copper Citrate 2 mg interact with drugs. Each result below shows which ingredient is responsible. Copper
Drospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Copper Citrate 2 mg — through 1 ingredient. Tap an ingredient for the detail:
CopperContraceptive Drugs Minor
Interaction Summary
Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
Read the full Copper + Drospirenone, Ethinyl Estradiol, Levomefolate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Copper Citrate 2 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Copper
Penicillamine (Cuprimine, Depen)
Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.
Contraceptive Drugs
Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.
Brand information
Manufacturer and brand details for Copper Citrate 2 mg, from the product label.
Copper Citrate 2 mg by Solaray: Common Questions
Does Copper Citrate 2 mg by Solaray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is copper citrate used for?
Can I take this if I'm pregnant or breastfeeding?
Are there any side effects?
I have diabetes. Is this supplement safe for me?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Copper Citrate 2 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Copper Citrate 2 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Copper Citrate 2 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Copper 11 references
- Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
- Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
- Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
- Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
- Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
- Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
- Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
- Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
- Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC