Cramp Bark Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Cramp Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cramp Bark is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, muscle spasms, general cramping pain.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cramp Bark by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Cramp Bark Bark Extract, a liquid herbal extract. The inactive ingredients are cane alcohol, distilled water, and glycerin — these are the base and preservative that keep the extract shelf-stable.
Does it work?
Insufficient evidence
The evidence we hold on cramp bark is insufficient to rate how well it works. Traditionally it's been used for muscle cramps, period pain (dysmenorrhea), pregnancy-related leg cramps, kidney stones, and diabetes — but we don't have reliable data to say whether it actually delivers results for any of those uses.
How safe is it?
Some data gaps
Cramp bark is generally used in traditional medicine, but human safety data are limited. We have no adverse effects documented in our data.
During pregnancy, the safety data advise against it. For breastfeeding, there isn't enough information — talk with your doctor or pharmacist before using it if you're nursing, so you can decide together what's right for you.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we checked.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
If you're looking for traditional herbal support and you're not pregnant or breastfeeding, cramp bark is generally well tolerated with no known medication interactions. Because evidence on how well it works is still unclear, manage your expectations — and let us know what you're taking so we can confirm there's no conflict.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cramp Bark, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700000448 |
| Net contents | 1 Fluid Ounce(s); 30 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 335844 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cramp Bark by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cramp Bark Bark Extract | 657 mg | -- |
Other ingredients: Cane Alcohol, Water, Distilled, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Viburnum opulus
Cramp Bark Liquid Extract
Formulation
System restoration Musculorskeletal
Gluten-free
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cramp Bark by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cramp Bark by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Cramp Bark Bark Extract
No knowninteractions
Cramp Bark is the dried bark of Viburnum opulus, traditionally used to ease muscle and menstrual cramps. Modern, high-quality human studies are very l...
Cramp Bark Bark Extract monograph & interactionsOther (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.
Cramp Bark by Herb Pharm Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cramp Bark. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cramp Bark, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Cramp Bark by Herb Pharm: Common Questions
Does Cramp Bark by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
Does this actually work for muscle cramps?
What's this extract made from?
Will this interfere with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cramp Bark is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cramp Bark’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cramp Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC