No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Cramp Bark Ingredients & Drug Interactions

by Herbalist & Alchemist

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Cramp Bark is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, muscle spasms, general cramping pain.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Cramp Bark by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: fresh Cramp Bark bark extract. Cramp Bark is a plant traditionally used to support muscle comfort, though the scientific evidence for its effectiveness is limited.

The liquid also includes ethyl alcohol, distilled water, and vegetable glycerin as inactive ingredients to deliver the extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Promotes muscle relaxation.
  • We looked for evidence on: Muscle cramps, Dysmenorrhea, Pregnancy-related leg cramps, Muscle spasms, Cramping pain.
  • The closest evidence on file: Cramp Bark is rated "Insufficient Reliable Evidence To Rate" for Muscle cramps (Natural Medicines).
  • Also on file: Cramp Bark is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea, Pregnancy-related leg cramps.

The evidence for Cramp Bark is not well established. We hold insufficient reliable evidence to rate it for muscle cramps, dysmenorrhea (menstrual pain), pregnancy-related leg cramps, diabetes, or kidney stones.

That doesn't mean it doesn't work — it means rigorous clinical trials backing its use for these purposes haven't been completed or aren't in our data.

The evidence, ingredient by ingredient Cramp Bark

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cramp Bark is generally used in traditional medicine, but human safety data are limited. The safety information on file advises against use during pregnancy and notes there isn't enough safety data for breastfeeding.

If you're pregnant, nursing, or planning either, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Cramp Bark

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredient we could check. Even so, if you take medications regularly, it's smart to run them through our interaction checker on this page before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

Cramp Bark may appeal to you if you're drawn to traditional herbal remedies for muscle comfort, but the scientific evidence for its effectiveness isn't established in our data. If you're pregnant, nursing, or take any medications, check with your own doctor or pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cramp Bark, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056110154
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 173986
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cramp Bark by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
3 mL
Servings per container
20
UPC/BARCODE
667056110154
IngredientAmount% DV
fresh Cramp Bark bark extract3 mL--

Other ingredients: Ethyl Alcohol, distilled Water, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Viburnum opulus

OK

General Statements

Promotes muscle relaxation

Botanical preparation ratio 1:3

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 40-60 drops (2-3 mL) in juice or water. Take 4 times per day. Shake well before using.

Precautions

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. CPB-2 1733WE

Seals/Symbols

OK

See for yourself

Cramp Bark by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cramp Bark by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container20 Amounts shown are per serving.

Fresh Cramp Bark bark extract

No known
interactions
3 mL per serving

Cramp Bark is the dried bark of Viburnum opulus, traditionally used to ease muscle and menstrual cramps. Modern, high-quality human studies are very l...

Fresh Cramp Bark bark extract monograph & interactions

Other (inactive) ingredients: Ethyl Alcohol, Distilled Water, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cramp Bark by Herbalist & Alchemist Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Cramp Bark. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Cramp Bark, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Cramp Bark by Herbalist & Alchemist: Common Questions

Does Cramp Bark by Herbalist & Alchemist interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Cramp Bark. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Cramp Bark contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cramp Bark while pregnant?
The safety data on file advise against it during pregnancy. Talk with your doctor or pharmacist about whether it's right for you in this situation.
Is it safe to breastfeed while taking Cramp Bark?
There isn't enough safety information for breastfeeding. Chat with your doctor or pharmacist to decide whether to use it while nursing.
Does Cramp Bark actually work for muscle cramps?
The evidence isn't established in our data. It's used traditionally, but rigorous clinical trials backing its use for cramps aren't on file — so we can't say whether it's effective.
What is Cramp Bark used for?
Traditionally, it's been used to support muscle comfort and ease menstrual discomfort, though scientific evidence for these uses is limited.
Does this product contain any fillers?
The liquid includes ethyl alcohol, distilled water, and vegetable glycerin as inactive ingredients to deliver the extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cramp Bark is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cramp Bark label
Go deeper

The Full Monographs Behind Cramp Bark’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Cramp Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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