No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Creatine Grape Flavor Ingredients & Drug Interactions

by Muscle Feast

Powder Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Creatine Grape Flavor is a dietary supplement by Muscle Feast with 1 active ingredient. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Creatine Grape Flavor by Muscle Feast

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is creatine monohydrate (Creapure brand), a single active ingredient. Creapure is a patented form of creatine that's been third-party tested for purity.

The powder also contains inactive ingredients — malic acid, citric acid, grape flavoring, acesulfame potassium, beet, blue spirulina, and sucralose — that handle taste, texture, and shelf life.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle strength and anaerobic athletic performance.
  • We looked for evidence on: Athletic performance, Muscle strength, Physical performance, Muscle breakdown, Postoperative recovery, Sarcopenia.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength, Sarcopenia.
  • Also on file: Creatine is rated "Insufficient Reliable Evidence To Rate" for Muscle breakdown, Physical performance, Postoperative recovery.

Creatine is possibly effective for building muscle strength, supporting muscle mass in sarcopenia (age-related muscle loss), improving athletic performance, and treating cerebral creatine deficiency syndromes. The evidence is less clear for Huntington disease and osteopenia, where it's rated possibly ineffective — meaning the research doesn't support benefit for those conditions.

If you're taking this for muscle strength or athletic performance in otherwise healthy adults, the science backs that use.

The evidence, ingredient by ingredient Creatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, creatine is generally well tolerated in healthy adults. The most common side effects are dehydration, diarrhea, stomach upset, muscle cramps, and water retention — usually mild and temporary.

Serious side effects are rare but have been reported in case studies: kidney inflammation, reduced kidney function, muscle breakdown, and blood clots. If you have kidney disease or reduced kidney function, talk with your doctor or pharmacist before starting.

Creatine should be avoided during pregnancy — safety hasn't been established. It should also be avoided while nursing because there isn't enough safety information for breastfeeding mothers.

If you're pregnant, planning pregnancy, or nursing, discuss this with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Creatine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the creatine in this product. That said, if you take any medication for your kidneys or heart, or if you're on a blood thinner, check with your doctor or pharmacist before starting — your own healthcare provider knows your medical history and can give you personalized guidance.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Creatine works for building muscle strength and athletic performance in healthy adults and is generally well tolerated. If you have kidney disease, are pregnant, or are nursing, steer clear or get personalized advice from your doctor or pharmacist first.

Even if you're healthy, make sure your exact medications aren't affected by running them through the checker below.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Creatine Grape Flavor, straight from the product label.

Brand Muscle Feast
Net contents 10.58 Ounce(s); 300 Gram(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261593
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Creatine Grape Flavor by Muscle Feast, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7.3 Gram(s)
Maximum serving Sizes:
7.3 Gram(s)
Servings per container
41
IngredientAmount% DV
Creapure5400 mg--

Other ingredients: Malic Acid, Citric Acid, Natural and Artificial Grape flavor, Acesulfame Potassium, Beet, Blue Spirulina, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

Dietary Supplement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Creapure 18MS12

Premium creatine with creapure

Formulation

99.9% Pure/Max strength & anaerobic power fuel

Precautions

Warning: This product is manufactured in a GMP compliant plant that processes milk.

Keep out of reach of children.

Do not exceed the recommended dose. Consult your physician before using this product.

Do not use this product if you are pregnant or nursing. Do not use this product if you are taking any prescription medication.

Do not use this product if you are under the age of 18.

Storage

Keep tightly closed in a cool, dry place away from sunlight.

General Statements

Ohio family owned business

See for yourself

Creatine Grape Flavor by Muscle Feast label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Creatine Grape Flavor by Muscle Feast

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size7.3 Gram(s) Dosage formPowder Servings per container41 Amounts shown are per serving.

Creapure

No known
interactions
5400 mg per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creapure monograph & interactions

Other (inactive) ingredients: Malic Acid, Citric Acid, Natural and Artificial Grape flavor, Acesulfame Potassium, Beet, Blue Spirulina, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Creatine Grape Flavor by Muscle Feast Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Creatine Grape Flavor. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Creatine Grape Flavor, from the product label.

Muscle Feast

See all Muscle Feast products
Name
Muscle Feast
Street Address
1320 Boston Road
City
Nashport
State
OH
ZipCode
43830
Phone Number
(888) 734-3634
Web Address
www.musclefeast.com
Pharmacist Counseling Corner

Creatine Grape Flavor by Muscle Feast: Common Questions

Does Creatine Grape Flavor by Muscle Feast interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Creatine Grape Flavor. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Creatine Grape Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will creatine make me gain weight?
Creatine pulls water into your muscles, so you may see a small increase on the scale — that's water retention, not fat. You'll also gain lean muscle mass over time if you're training, which adds real weight. Most people notice both effects together.
Can I take this if I have high blood pressure?
The product facts don't mention blood pressure interactions with creatine. That said, creatine does cause water retention, which can affect blood pressure in some people. Talk with your doctor or pharmacist before starting — they know your specific situation and can advise you.
What are the most common side effects?
Dehydration, diarrhea, stomach upset, muscle cramps, and water retention are the most common. They're usually mild and go away with time. Drinking plenty of water helps prevent several of these.
How long does it take to see results?
The product facts don't specify a timeline for when you'll notice improvements in muscle strength or athletic performance. That varies by person, your training, and your diet — talk with your doctor or a trainer about what to expect.
Is this safe if I have kidney problems?
No — the safety data advises caution if you have kidney issues because creatine is processed through your kidneys. Talk with your doctor or pharmacist before taking this if you have any kidney disease or reduced kidney function.
Can I take this while pregnant or breastfeeding?
No — safety during pregnancy has not been established, so it should be avoided. There also isn't enough safety information for nursing mothers, so avoid it while breastfeeding. Discuss with your doctor or pharmacist if you have questions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Creatine Grape Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Creatine Grape Flavor label
Go deeper

The Full Monographs Behind Creatine Grape Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Creatine Grape Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 86 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
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  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
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  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
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  13. Juhn MS, O'Kane JW, Vinci DM. Oral creatine supplementation in male collegiate athletes: a survey of dosing habits and side effects. J Am Diet Assoc 1999;99:593-5.
  14. Green AL, Hultman E, Macdonald IA, et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol 1996;271:E821-6. PubMed
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  22. Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D., and Chinnery, P. F. Treatment for mitochondrial disorders. Cochrane Database.Syst.Rev. 2012;4:CD004426. PubMed
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  26. Volek, J. S., Duncan, N. D., Mazzetti, S. A., Putukian, M., Gomez, A. L., and Kraemer, W. J. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr.Exerc.Metab 2000;10(2):144-156. PubMed
  27. Robinson, T. M., Sewell, D. A., Casey, A., Steenge, G., and Greenhaff, P. L. Dietary creatine supplementation does not affect some haematological indices, or indices of muscle damage and hepatic and renal function. Br.J Sports Med 2000;34(4):284-288. PubMed
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  29. Tarnopolsky, M. A. and MacLennan, D. P. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr.Exerc.Metab 2000;10(4):452-463. PubMed
  30. Arciero, P. J., Hannibal, N. S., III, Nindl, B. C., Gentile, C. L., Hamed, J., and Vukovich, M. D. Comparison of creatine ingestion and resistance training on energy expenditure and limb blood flow. Metabolism 2001;50(12):1429-1434. PubMed
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  32. Cox, G., Mujika, I., Tumilty, D., and Burke, L. Acute creatine supplementation and performance during a field test simulating match play in elite female soccer players. Int J Sport Nutr.Exerc.Metab 2002;12(1):33-46. PubMed
  33. Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., and Pitsiladis, Y. P. Effects of creatine on isometric bench-press performance in resistance-trained humans. Med Sci.Sports Exerc. 2002;34(7):1176-1183. PubMed
  34. Brose, A., Parise, G., and Tarnopolsky, M. A. Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. J Gerontol A Biol.Sci.Med Sci. 2003;58(1):11-19. PubMed
  35. Volek, J. S., Ratamess, N. A., Rubin, M. R., Gomez, A. L., French, D. N., McGuigan, M. M., Scheett, T. P., Sharman, M. J., Hakkinen, K., and Kraemer, W. J. The effects of creatine supplementation on muscular performance and body composition responses to
  36. Tyler, T. F., Nicholas, S. J., Hershman, E. B., Glace, B. W., Mullaney, M. J., and McHugh, M. P. The effect of creatine supplementation on strength recovery after anterior cruciate ligament (ACL) reconstruction: a randomized, placebo-controlled, double-b DOI
  37. Groeneveld, G. J., Beijer, C., Veldink, J. H., Kalmijn, S., Wokke, J. H., and van den Berg, L. H. Few adverse effects of long-term creatine supplementation in a placebo-controlled trial. Int J Sports Med 2005;26(4):307-313. PubMed
  38. Astorino, T. A., Marrocco, A. C., Gross, S. M., Johnson, D. L., Brazil, C. M., Icenhower, M. E., and Kneessi, R. J. Is running performance enhanced with creatine serum ingestion? J Strength.Cond.Res 2005;19(4):730-734. PubMed
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  43. Koenig CA, Benardot D Cody M Thompson WR. Comparison of creatine monohydrate and carbohydrate supplementation on repeated jump height performance. J Strength Cond Res. 2008;22(4):1081-1086. PubMed
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  45. Bender, A., Samtleben, W., Elstner, M., and Klopstock, T. Long-term creatine supplementation is safe in aged patients with Parkinson disease. Nutr.Res. 2008;28(3):172-178. PubMed
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  48. Saidi, H. and Mani, M. Severe metabolic acidosis secondary to coadministration of creatine and metformin, a case report. Am.J.Emerg.Med. 2010;28(3):388-6. PubMed
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  50. Neves, M., Jr., Gualano, B., Roschel, H., Lima, F. R., Lucia, de Sa-Pinto, Seguro, A. C., Shimizu, M. H., Sapienza, M. T., Fuller, R., Lancha, A. H., Jr., and Bonfa, E. Effect of creatine supplementation on measured glomerular filtration rate in postmeno
  51. Gufford, B. T., Sriraghavan, K., Miller, N. J., Miller, D. W., Gu, X., Vennerstrom, J. L., and Robinson, D. H. Physicochemical characterization of creatine N-methylguanidinium salts. J.Diet.Suppl 2010;7(3):240-252.
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  70. The Associated Press. Creatine ruled out in athletes' deaths. The New York Times. May 2, 1998. Available at: http://www.nytimes.com/1998/05/02/sports/plus-college-wrestling-creatine-ruled-out-in-athletes-deaths.html.
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See these in context on the Creatine monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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