No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

D-Biotin 1000 mcg Ingredients & Drug Interactions

by Kirkman

D-Biotin 1000 mcg label
See full label image
Capsule Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Biotin 1000 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

D-Biotin 1000 mcg is a dietary supplement by Kirkman with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of D-Biotin 1000 mcg by Kirkman

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-biotin, a B vitamin that your body needs to break down and use fats, carbohydrates, and amino acids. The capsule itself is made from plant cellulose, and the filler is microcrystalline cellulose — both inactive ingredients that help deliver the biotin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Biotin's overall clinical evidence instead.

Strong

Strong clinical evidence supports Biotin for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Biotin deficiency — rated "Likely Effective" (Natural Medicines).

D-biotin is likely effective for treating biotin deficiency, which is rare but can happen with certain medical conditions or medications. For other uses — multiple sclerosis, seborrheic dermatitis (a scaly skin condition), and hair loss (alopecia areata) — the evidence is either possibly ineffective or there isn't enough reliable data to say whether it works.

If you're thinking about biotin for something other than deficiency, talk with your doctor about whether it's the right choice for you.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body excretes any excess in your urine. High-dose biotin has rarely caused mild diarrhea.

One uncommon case report linked very high doses of biotin (10 mg daily, much higher than this product) combined with another supplement to a heart and lung inflammation, but it's unclear whether biotin was the cause. Because this is a high-dose product (1000 mcg), the safety data advises checking with your doctor before starting it — normal dietary and supplement amounts are fine, but discuss high-dose products first.

Biotin is likely safe in pregnancy and lactation at normal amounts.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, it's smart to verify your exact medications with your pharmacist or the checker on this page.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This biotin supplement makes sense if you've been diagnosed with biotin deficiency or your doctor has recommended it. Because it's a high-dose formulation, run it by your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have any health concerns.

No medication interactions are documented, but your pharmacist can double-check your specific drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Biotin 1000 mcg, straight from the product label.

Brand Kirkman
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 24054
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Biotin 1000 mcg by Kirkman, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
IngredientAmount% DV
D-Biotin1000 mcg333%

Other ingredients: Microcrystalline Cellulose, Plant Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

(503)694-1600

Formula

HYPOALLERGENIC

Suggested/Recommended/Usage/Directions

SUGGESTED USE: One capsule daily or as directed by your physician.

General

382/120

Formulation

FREE OF: Sugar, starch, soy, wheat, casein, gluten, milk, corn, preservatives, yeast, gelatin, tree nuts, fish, flavorings, or colorings.

CASEIN & GLUTEN FREE

Storage

IMPORTANT: STORE IN A COOL DRY PLACE AND TIGHTLY CAPPED.

FDA Statement of Identity

Dietary Supplement

Precautions

KEEP OUT OF THE REACH OF CHILDREN.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Biotin 1000 mcg by Kirkman label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Biotin 1000 mcg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Biotin 1000 mcg by Kirkman

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

D-Biotin

No known
interactions
1000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

D-Biotin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Plant Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Biotin 1000 mcg by Kirkman Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in D-Biotin 1000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for D-Biotin 1000 mcg, from the product label.

Kirkman

See all Kirkman products
Name
Kirkman
City
Lake Oswego
State
OR
ZipCode
97035
Phone Number
(800) 245-8282
Web Address
www.kirkmangroup.com
Pharmacist Counseling Corner

D-Biotin 1000 mcg by Kirkman: Common Questions

Does D-Biotin 1000 mcg by Kirkman interact with any medications?
We do not currently list a known interaction for the mapped ingredients in D-Biotin 1000 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
D-Biotin 1000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will biotin help with hair loss?
There isn't enough reliable evidence to say whether biotin helps alopecia areata (patchy hair loss). If that's why you're considering it, talk with your doctor first — they can advise whether it's worth trying for your situation.
Can I take this at such a high dose?
Biotin is well tolerated even at high doses because your body removes excess through urine. That said, the safety data suggests checking with your doctor before taking high-dose biotin supplements — normal dietary and supplement amounts don't need that step, but this 1000 mcg product does.
Is biotin safe if I'm pregnant or breastfeeding?
Yes, biotin is likely safe in pregnancy and lactation. Normal dietary amounts and typical prenatal vitamins contain biotin without concern, but if you're considering a high-dose supplement like this one, talk with your doctor first to be sure it's right for you.
What's the difference between D-biotin and biotin?
D-biotin is the form of biotin your body uses. It's the standard, active form you'll see in supplements.
Has anyone had side effects from biotin?
High-dose biotin has rarely caused mild diarrhea. One uncommon case report described inflammation of the heart and lungs in someone taking a much larger dose (10 mg daily) along with other supplements, but it's unclear what caused it. Overall, biotin is generally well tolerated.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Biotin 1000 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Biotin 1000 mcg label
Go deeper

The Full Monographs Behind D-Biotin 1000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph →
Sources

Sources & How We Checked

D-Biotin 1000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team