No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

D-Glucuronolactone Ingredients & Drug Interactions

by BulkSupplements.com

D-Glucuronolactone label
See full label image
Powder Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Glucuronolactone against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

D-Glucuronolactone is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for energy and stamina, mental focus and alertness, reducing fatigue.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of D-Glucuronolactone by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-Glucuronolactone, a compound your body naturally makes and uses in detoxification and waste removal. The powder form lets you mix it into beverages.

There are no inactive fillers or other ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Glucuronolactone product and its label doesn't state a use — see Glucuronolactone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness ratings for D-Glucuronolactone in our data, so we can't tell you from this source how well it works or what it's proven to do.

The evidence, ingredient by ingredient Glucuronolactone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-Glucuronolactone is generally well tolerated when you use it in amounts typical of energy drinks and similar beverages. That said, long-term safety and the effects of high doses haven't been well studied, so we can't promise it's safe at any dose indefinitely.

During pregnancy, there isn't enough safety data to know either way — talk with your doctor or pharmacist about whether to use it. The same goes for breastfeeding: there's no reliable safety information, so avoidance is the more cautious choice.

If you're in either situation and want to use this product, discuss it with your healthcare provider first.

Side effects, ingredient by ingredient Glucuronolactone

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That's not a guarantee none exist, so if you take any medications, mention this product to your doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.

If you're taking medications, this product doesn't have documented interactions with them. But because long-term and high-dose safety isn't well studied, this is worth mentioning to your doctor or pharmacist — especially if you're pregnant, nursing, or planning to use it regularly at high doses.

They can give you personalized advice based on your health.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Glucuronolactone, straight from the product label.

Brand BulkSupplements.com
Net contents 100 Gram(s); 3.53 Ounce(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 253442
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Glucuronolactone by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 Milligram(s)
Maximum serving Sizes:
1000 Milligram(s)
Servings per container
100
IngredientAmount% DV
D-Glucuronolactone1000 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Clean & Pure Bulk Supplements

US Standard Measuring Spoons Spoon Size (level) milligrams 1/8 teaspoon 485 1/4 teaspoon 970 1/2 teaspoon 1940

Precautions

Warning: Not intended for individuals who are diabetic or hypoglycemic.

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Free of: Sugar, soy, dairy, yeast, gluten or additives

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 500 mg to 1000 mg (rounded 1/4 tsp) one to three times daily, or as directed by a physician. Best taken on an empty stomach.

Storage

Keep dry, cool & dark

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Glucuronolactone by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Glucuronolactone label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Glucuronolactone by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 Milligram(s) Dosage formPowder Servings per container100 Amounts shown are per serving.

D-Glucuronolactone

No known
interactions
1000 mg per serving

Glucuronolactone is a naturally occurring compound that is commonly added to energy drinks and supplements, often alongside caffeine and taurine. Ther...

D-Glucuronolactone monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Glucuronolactone by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in D-Glucuronolactone. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for D-Glucuronolactone, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Road
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

D-Glucuronolactone by BulkSupplements.com: Common Questions

Does D-Glucuronolactone by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in D-Glucuronolactone. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
D-Glucuronolactone contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is D-Glucuronolactone safe during pregnancy?
There isn't enough safety data to know either way. If you're pregnant and want to take this product, talk with your doctor or pharmacist first — they can give you personalized advice.
Can I use this while breastfeeding?
There's no reliable safety information for breastfeeding, so avoidance is the safer choice. If you'd like to use it anyway, check with your doctor or pharmacist first.
What does D-Glucuronolactone do in the body?
It's a compound your body naturally makes and uses in detoxification and waste removal — basically part of your cleanup system. But how much benefit you get from taking it as a supplement isn't clear from our data.
Are there any side effects from D-Glucuronolactone?
We don't have adverse effect data on file for this ingredient, so we can't tell you from that source what to expect. What we do know is that it's generally well tolerated in beverage-like amounts.
Is it safe to take this long-term or at high doses?
Long-term safety and the effects of high doses haven't been well studied, so we don't have solid data on that. If you're planning to use this regularly or at higher amounts, talk with your pharmacist or doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Glucuronolactone is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Glucuronolactone label
Go deeper

The Full Monographs Behind D-Glucuronolactone’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucuronolactone

Glucuronolactone is a naturally occurring compound that is commonly added to energy drinks and supplements, often alongside caffeine and taurine. There is very little solid human evidence th...

Read the full Glucuronolactone monograph →
Sources

Sources & How We Checked

D-Glucuronolactone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glucuronolactone 2 references
  1. Caffeine and Energy Drinks — NIH National Center for Complementary and Integrative Health Source
  2. Caffeine — MedlinePlus Source

See these in context on the Glucuronolactone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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