D-Mannose Ingredients & Drug Interactions
What is this page for?
First and foremost: checking D-Mannose against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
D-Mannose is a dietary supplement by Woodstock Vitamins with 1 active ingredient. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of D-Mannose by Woodstock Vitamins
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: D-mannose, a naturally occurring simple sugar. D-mannose works by being filtered through your kidneys into your urine, where it may help prevent bacteria from adhering to the bladder lining.
There are no inactive ingredients listed for this product — it's just the D-mannose itself.
Does it work?
Leans against
The evidence for D-mannose is mixed. For carbohydrate-deficient glycoprotein syndrome type 1b — a rare genetic condition affecting how your body makes certain proteins — D-mannose is considered likely effective.
For urinary tract infections (UTIs), however, the evidence suggests it's possibly ineffective, meaning the current data don't support its use for that purpose.
How safe is it?
Well-documented data
D-mannose is generally well tolerated in the short term, but we don't have high-quality long-term safety data, so we can't say much about what happens if you take it for months or years. The most common side effects are bloating, diarrhea, and nausea — especially at higher doses.
Taking a single dose above 200 mg per kilogram of body weight is more likely to trigger osmotic diarrhea (loose stools from the sugar drawing water into your intestines). If you're pregnant, there isn't enough reliable safety data, so it's best to avoid this supplement unless your doctor specifically advises you to take it.
The same caution applies to breastfeeding — safety data are limited, so talk with your doctor or pharmacist before using it while nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for D-mannose. However, it's always smart to mention any new supplement to your doctor or pharmacist, especially if you take medications that affect your kidneys or blood sugar.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
D-mannose is a simple sugar used mainly for a rare genetic condition where it has solid evidence. If you're considering it for UTIs, the data don't support that use.
The supplement is generally well tolerated short-term, but long-term safety isn't well established, and it can cause digestive upset — especially at higher doses. Talk with your pharmacist about whether it makes sense for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about D-Mannose, straight from the product label.
| Brand | Woodstock Vitamins |
|---|---|
| Barcode (UPC) | 669439792711 |
| Net contents | 1.66 Ounce(s); 47 Gram(s) |
| Market status | On market |
| Date entered into DSLD | May 23, 2024 |
| DSLD ID | 310194 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for D-Mannose by Woodstock Vitamins, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| D-Mannose | 900 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: Mix one scoop in 2-4 oz of water one to three times daily, or as directed by your healthcare practitioner.
Precautions
Consult your healthcare practitioner prior to use. Do not use if tamper seal is damaged.
Individuals taking medication should discuss potential interactions with their healthcare practitioner.
Professional Use Only
Formula
D-Mannose features D-mannose, a simple sugar that occurs naturally in cranberries and pineapple. Research suggests that D-mannose interferes with adhesion of E coli to the bladder wall, thereby supporting a healthy urinary tract.
Featuring D-Mannose
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Storage: Keep closed in a cool, dry place out of reach of children.
Formulation
Does not contain: wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Concentrated urinary tract support
Manufactured in a GMP compliant facility.
FDA Statement of Identity
Dietary Supplement
General Statements
This package is completely recyclable
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
D-Mannose by Woodstock Vitamins label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in D-Mannose by Woodstock Vitamins
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size936 mg Dosage formPowder Servings per container50 Amounts shown are per serving.
D-Mannose
No knowninteractions
D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...
D-Mannose monograph & interactionsD-Mannose by Woodstock Vitamins Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in D-Mannose. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for D-Mannose, from the product label.
Woodstock Vitamins
See all Woodstock Vitamins products- Name
- Village Vitality LLC
- Street Address
- 79 Tinker Street Fl 2
- City
- Woodstock
- State
- NY
- ZipCode
- 12498
- Phone Number
- (845) 521-7455
- Web Address
- www.WoodstockVitamins.com
D-Mannose by Woodstock Vitamins: Common Questions
Does D-Mannose by Woodstock Vitamins interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will D-mannose help my UTI?
What are the side effects?
Is it safe to take long-term?
Can I take it while pregnant?
Is it safe while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if D-Mannose is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind D-Mannose’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
D-Mannose's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
D-mannose 6 references
- Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
- Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
- de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
- Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
- . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
- Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC