No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

D-Mannose Pure Powder Ingredients & Drug Interactions

by LuckyVitamin

Powder Category: Fiber And Other Nutrients
No known interaction
The interaction bottom line No known interaction

D-Mannose Pure Powder is a dietary supplement by LuckyVitamin with 1 active ingredient. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of D-Mannose Pure Powder by LuckyVitamin

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: D-mannose, a simple sugar (carbohydrate) that your body handles differently than glucose. The powder form lets you mix it into water or another drink and adjust your dose easily.

There are no other inactive ingredients listed.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: help cleanse urinary tract and maintain bladder lining.
  • We looked for evidence on: Urinary tract infections (UTIs), urinary tract health, bladder health.
  • The closest evidence on file: D-mannose is rated "Possibly Ineffective" for Urinary tract infections (UTIs) (Natural Medicines).

D-mannose is likely effective for carbohydrate-deficient glycoprotein syndrome type 1b, a rare inherited condition affecting how your body makes certain proteins. For urinary tract infections (UTIs), the evidence rates as possibly ineffective — meaning it hasn't shown reliable benefit in the studies we have on file.

The evidence, ingredient by ingredient D-mannose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-mannose is generally well tolerated in the short term, but long-term safety data are limited, so caution is advised if you're thinking of taking it for months on end. The most common side effects are bloating, diarrhea, and nausea.

Diarrhea is more likely if you take a single dose greater than 200 mg/kg (a dose-dependent effect related to how your gut absorbs it). During pregnancy, there isn't enough reliable safety data, so it's best to avoid it unless your doctor advises otherwise.

Safety while breastfeeding is also not well studied, so caution is advised — talk it over with your doctor or pharmacist if you're nursing.

Side effects, ingredient by ingredient D-mannose

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for D-mannose. Before you start, run your medications through the checker on this page, and let your doctor or pharmacist know you're adding this supplement.

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

D-mannose is a simple sugar used mainly for carbohydrate-deficient glycoprotein syndrome type 1b. If you're considering it for UTIs, the evidence doesn't support it.

Most people tolerate it short-term, but watch for bloating and loose stools, and don't take high single doses. If you're pregnant, nursing, or taking any regular medications, check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Mannose Pure Powder, straight from the product label.

Brand LuckyVitamin
Barcode (UPC) 810026421044
Net contents 6 Ounce(s); 170 Gram(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283162
Product type Fiber And Other Nutrients
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Mannose Pure Powder by LuckyVitamin, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
85
UPC/BARCODE
810026421044
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)1%
Total Sugars2 Gram(s)--
D-Mannose2 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 level teaspoon 1 to 2 times daily. Take with water or unsweetened juice, such as unsweetened cranberry juice.

Formula

D-mannose is a naturally occurring simple sugar that your body utilizes to help cleanse the urinary tract and maintain a healthy bladder lining. It's metabolized only in small amounts, with excess amounts rapidly excreted in urine, so it won't interfere with healthy blood sugar regulation. Clinical studies have demonstrated that, when taken regularly, D-mannose promotes normal urinary tract function by cleansing and maintaining the health of the bladder lining.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet enclosed. Keep in bottle.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Keep bottle tightly closed at all times in between usage. Do not eat freshness packet enclosed. Keep in bottle.

Store in a cool, dry place after opening.

Formulation

Natural color variation may occur in this product.

Certified Organic by QAI

V Vegan

Certified organic D-mannose pure powder

Healthy urinary tract Cleanses the bladder

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

FDA Statement of Identity

Dietary Supplement

General Statements

This product is sold by weight not volume.

1 year happiness guarantee

Seals/Symbols

Guaranteed Quality & Potency

See for yourself

D-Mannose Pure Powder by LuckyVitamin label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in D-Mannose Pure Powder by LuckyVitamin

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container85 Amounts shown are per serving.

D-Mannose

No known
interactions
2 Gram(s) per serving

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...

D-Mannose monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Mannose Pure Powder by LuckyVitamin Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in D-Mannose Pure Powder. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for D-Mannose Pure Powder, from the product label.

LuckyVitamin

See all LuckyVitamin products
Name
Lucky Health Group Inc.
City
Conshohocken
State
PA
ZipCode
19428
Phone Number
1-888-635-0474
Web Address
www.LuckyVitamin.com
Pharmacist Counseling Corner

D-Mannose Pure Powder by LuckyVitamin: Common Questions

Does D-Mannose Pure Powder by LuckyVitamin interact with any medications?
We do not currently list a known interaction for the mapped ingredients in D-Mannose Pure Powder. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
D-Mannose Pure Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does D-mannose actually help with UTIs?
The evidence rates it as possibly ineffective for urinary tract infections — meaning studies haven't shown it reliably works for that purpose. If you're dealing with a UTI, talk to your doctor about proven treatments.
What are the most common side effects?
Bloating, diarrhea, and nausea are the most common. Diarrhea is dose-dependent — a single dose over 200 mg/kg is more likely to cause it. Most people tolerate it well short-term.
Is it safe to take long-term?
Short-term use is generally well tolerated, but long-term safety data are limited. If you're thinking about taking it for months, talk with your doctor or pharmacist first.
Can I take this while pregnant or breastfeeding?
During pregnancy, there isn't enough reliable safety data, so it's best to avoid it unless your doctor advises otherwise. Safety while breastfeeding is also not well studied, so caution is advised — check with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Mannose Pure Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Mannose Pure Powder label
Go deeper

The Full Monographs Behind D-Mannose Pure Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

D-Mannose Pure Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

D-mannose 6 references
  1. Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
  2. Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
  3. de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
  4. Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
  5. . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
  6. Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed

See these in context on the D-mannose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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