Detoxadine Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Detoxadine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Detoxadine is a dietary supplement by Global Healing with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Detoxadine by Global Healing
Ask about any prescription or over-the-counter medication and we check it for interactions with Detoxadine by Global Healing — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Detoxadine by Global Healing
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Detoxadine contains one active ingredient: iodine. The supplement is delivered in a liquid form with glycerin and distilled water as inactive ingredients.
Does it work?
Strong evidence
Iodine is likely effective for preventing and treating iodine deficiency and for protecting the thyroid and mouth tissues from radiation exposure. It's possibly effective for oral mucositis (mouth sores) and periodontitis (gum disease), though the evidence is less complete for those uses.
How safe is it?
Well-documented data
Iodine is generally well tolerated in normal dietary amounts, but high doses can cause thyroid problems—including both an overactive thyroid and an underactive one. The most common side effects from oral iodine are abdominal upset, diarrhea, nausea, metallic taste, headache, and goiter (thyroid swelling).
Rare serious reactions include hypersensitivity symptoms such as angioedema (severe facial swelling) and anaphylaxis. Chronic or very large amounts can cause acneform skin lesions called iododerma.
For pregnancy and breastfeeding, the safety data advises caution. Adequate iodine is important during pregnancy, but use only the amount your doctor recommends and avoid high-dose products.
Some iodine is needed for the baby during breastfeeding, but excess can pass into breast milk, so follow your doctor's guidance.
Meds to double-check
Moderate interaction found
Before taking Detoxadine, check whether you're on lithium (mood disorders), antithyroid drugs (overactive thyroid), or amiodarone (Cordarone, heart rhythm). All three are Moderate severity interactions with iodine.
Altogether, these interactions span 7 individual medications.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Detoxadine is useful if you have an iodine deficiency or need thyroid protection after radiation. If you take lithium, antithyroid drugs, or amiodarone, you need to check with your pharmacist or doctor first—iodine can interfere with how these work.
In pregnancy or while breastfeeding, talk to your doctor about what amount is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Detoxadine, straight from the product label.
| Brand | Global Healing |
|---|---|
| Barcode (UPC) | 811839030133 |
| Net contents | 1 Fluid Ounce(s); 29.6 Milliliter(s) |
| Market status | On market |
| Date entered into DSLD | Apr 24, 2025 |
| DSLD ID | 330745 |
| Product type | Mineral |
| Supplement form | Liquid |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Detoxadine by Global Healing, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Iodine | 1950 mcg | 1300% |
Other ingredients: Glycerin, Water, Distilled
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Take 3 drops, immediately follow with purified water and swallow. Use once daily or as recommended by your healthcare provider.
Formulation
Boost thyroid health
Detoxadine is organic nascent iodine used to support thyroid health, detoxification, and hormone balance.
Vegan-Friendly
Gluten-free Sugar-free Alcohol-free
No animal testing
Healthy thyroid, detox, and hormone balance
USDA Organic US-ORG-030
Non GMO Project Verified nongmoproject.org
High-purity iodine sourced in the USA
Certified organic by Natural Food Certifiers.
Formula
Detoxadine is organic nascent iodine used to support thyroid health, detoxification, and hormone balance.
Nascent Iodine
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
USDA Organic Non GMO Project Verified nongmoproject.org
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Detoxadine by Global Healing label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Detoxadine by Global Healing
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Drop(s) Dosage formLiquid Servings per container200 Amounts shown are per serving.
Iodine
Interacts with7 drugs
Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...
Iodine monograph & interactionsOther (inactive) ingredients: Glycerin, Water, Distilled. These complete the product’s ingredient list but are not active constituents.
Detoxadine by Global Healing Drug Interactions
HelloPharmacist Interaction Report
Detoxadine by Global Healing is a single-ingredient iodine supplement that does interact with several medications, most notably with lithium, which is used to treat bipolar disorder and other mood conditions.
Read the full breakdown — every affected drug type, severity by severity
Lithium can slow thyroid function on its own, and adding iodine may worsen that effect. Case reports show that lithium plus iodine together can reduce thyroid function in otherwise healthy people, so thyroid monitoring is important if you're on both.
Antithyroid drugs (used to treat overactive thyroid) may also have their effects altered by iodine, since iodine itself can swing thyroid function in either direction depending on your history. Similarly, amiodarone (Cordarone), a heart rhythm medication that's about 37% iodine by weight, can push iodine levels too high when combined with this supplement, risking thyroid damage.
Alternative heart and thyroid medications exist in the data we hold. Before you start Detoxadine, check your exact medications against the interaction checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Detoxadine?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Detoxadine interact with 7 drugs. Click any drug to see the details.
1 of the 1 ingredient in Detoxadine interact with drugs. Each result below shows which ingredient is responsible. Iodine
AmiodaroneCordarone, Pacerone
How Amiodarone interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAmiodarone (cordarone) Moderate
Interaction Summary
Combining iodine with amiodarone might cause excessively high iodine levels.
Read the full Iodine + Amiodarone interactionCarbimazoleNeo-Mercazole
How Carbimazole interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Carbimazole interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineLithium Moderate
Interaction Summary
Combining iodine with lithium might have additive hypothyroid effects.
Read the full Iodine + Lithium Carbonate (prescription Drug) interactionMethenamine MandelateMandelamine, Methimazole
How Methenamine Mandelate interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Methenamine Mandelate interactionMethimazoleTapazole
How Methimazole interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Methimazole interactionPotassium Iodide (prescription Drug)Thyro-Block
How Potassium Iodide (prescription Drug) interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Potassium Iodide (prescription Drug) interactionPropylthiouracil, PtuPropylthiouracil
How Propylthiouracil, Ptu interacts with Detoxadine — through 1 ingredient. Tap an ingredient for the detail:
IodineAntithyroid Drugs Moderate
Interaction Summary
Iodine might alter the effects of antithyroid drugs.
Read the full Iodine + Propylthiouracil, Ptu interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Detoxadine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Iodine
Amiodarone (Cordarone)
Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.
Brand information
Manufacturer and brand details for Detoxadine, from the product label.
Global Healing
See all Global Healing products- Name
- Global Healing Center, LLC.
- City
- Houston
- State
- TX
- ZipCode
- 77055
- Phone Number
- 1.800.476.0016
- Web Address
- globalhealing.com
Detoxadine by Global Healing: Common Questions
Does Detoxadine by Global Healing interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is iodine used for in this product?
Can I take this if I'm pregnant?
Can I take this while breastfeeding?
What are the most common side effects?
Is this safe to take long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Detoxadine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Detoxadine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Detoxadine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iodine 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
- Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
- Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
- Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
- Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
- Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
- Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
- Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
- Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
- Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
- Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
- Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
- Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
- Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
- Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
- Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
- Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
- Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
- Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
- Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
- Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
- Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
- Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC