No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Devil's Club Ingredients & Drug Interactions

by Herbalist & Alchemist

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Devil's Club is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, respiratory and cold symptoms, arthritis and joint pain.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Devil's Club by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dried Devil's Club root bark extract. Devil's Club is a plant traditionally used in herbal medicine; the extract here comes from the root and bark.

The liquid form also holds ethyl alcohol and distilled water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports pancreatic function.
  • We looked for evidence on: pancreatic health, glucose metabolism, insulin function, endocrine support.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness ratings for Devil's Club in our data. That means the scientific evidence for what this ingredient does isn't established in the monograph we have on file.

If you're considering it for a specific health goal, your doctor or pharmacist can point you toward what the current research actually shows.

The evidence, ingredient by ingredient Devil's Club

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Devil's Club has limited safety data in humans, so use it cautiously and with professional guidance. When taken by mouth, it might cause diarrhea, nausea, vomiting, and lightheadedness.

One case involved severe nausea and vomiting after someone drank two large servings within 5 hours. Applied to the skin, it may trigger allergic reactions in some people.

During pregnancy, there isn't enough safety information — it's best avoided. The same goes for breastfeeding — safety hasn't been studied in nursing mothers, so don't use it while nursing.

Side effects, ingredient by ingredient Devil's Club

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Devil's Club. That said, the ingredient has limited human safety data overall, so check with your own doctor or pharmacist before starting it alongside any medications you take.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Devil's Club is a traditional plant extract with very limited safety data in people. It's not proven to work for any specific condition in our data, and it can cause digestive upset and other side effects.

If you're interested in it, talk with your doctor or pharmacist first — especially if you're pregnant, nursing, or take any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Devil's Club, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056111052
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 174513
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Devil's Club by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1.5 mL
Servings per container
40
UPC/BARCODE
667056111052
IngredientAmount% DV
dried Devil's Club root bark extract1.5 mL--

Other ingredients: Ethyl Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Oplopanax horridus

OK

General Statements

Supports pancreatic function

Botanical preparation ratio 1:4

Keep out of children's reach

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 20-30 drops (1-1.5 mL) in juice or water. Take 3 times per day. Shake well before using.

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. OPX-2 1725FR

Seals/Symbols

OK

See for yourself

Devil's Club by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Devil's Club by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container40 Amounts shown are per serving.

1.5 mL per serving

Devil's Club is a thorny shrub from the Pacific Northwest of North America that has long been used in Indigenous traditional medicine, especially for...

Dried Devil's Club root bark extract monograph & interactions

Other (inactive) ingredients: Ethyl Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Devil's Club by Herbalist & Alchemist Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Devil's Club. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Devil's Club, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Devil's Club by Herbalist & Alchemist: Common Questions

Does Devil's Club by Herbalist & Alchemist interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Devil's Club. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Devil's Club contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Devil's Club if I'm pregnant?
No — there isn't enough safety information during pregnancy, so it's best avoided. Talk with your doctor or pharmacist about what's safe for you.
Is it safe to use while breastfeeding?
Safety hasn't been studied in nursing mothers, so you should avoid it while breastfeeding. Check with your doctor or pharmacist for alternatives that are known to be safe.
What side effects might I experience?
Taken by mouth, Devil's Club might cause diarrhea, nausea, vomiting, and lightheadedness. If you apply it to your skin, it may cause allergic reactions in some people.
Does Devil's Club actually work for anything?
We don't hold effectiveness ratings for it in our data, so the scientific evidence for what it does isn't established in our monograph. Talk with your doctor about whether research supports its use for what you're interested in.
Why does the label say to use it under professional guidance?
Devil's Club has limited safety data in humans. Using it with guidance from a doctor or pharmacist helps make sure it's appropriate for your situation and won't cause problems with other things you're taking or health conditions you have.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Devil's Club is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Devil's Club label
Go deeper

The Full Monographs Behind Devil's Club’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Devil's Club's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Devil's Club 2 references
  1. Turner NJ, Thompson LC Thompson MT York AZ. Thompson Ethnobotany: Knowledge and Usage of Plants by the Thompson Indians of British Columbia. 1990.
  2. Thommasen HV, Wilson RA, McIlwain RG. Effect of Devil's Club Tea on Blood Glucose Levels in Diabetes Mellitus. Can Fam Physician. 1990;36:62-5.

See these in context on the Devil's Club monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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