No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 9 ingredients. Check your meds →
Dietary supplement

DGST Ingredients & Drug Interactions

by Loomis Enzymes

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

DGST is a dietary supplement by Loomis Enzymes with 9 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of DGST by Loomis Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (244 mg) without saying how much of each component you get.

DGST contains 9 active digestive enzymes designed to help break down food. Protease breaks down proteins, lipase handles fats, and lactase is the enzyme that breaks down the milk sugar (lactose).

Cellulase, amylase, and the others work on different carbohydrates and fiber. Together they're meant to ease the work your digestive system does on its own.

The product also contains several inactive ingredients — phytase, cellulose, and water — which are fillers and capsule materials.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digestive support with pH balancing.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating, Gas.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is rated effective for lactose intolerance — if you have trouble digesting milk products, lactase can help. The evidence for the other enzymes — protease, lipase, and the rest — on conditions like upset stomach (dyspepsia) or inflammatory bowel disease (IBD) is currently insufficient.

That means the research isn't there yet to say whether they work for those purposes, not that they don't.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated in most adults, though some people report mild digestive upset or, rarely, allergic reactions. Lactase is similarly well tolerated.

If you have a serious digestive condition, check with your doctor before starting any enzyme supplement. For pregnancy, the safety data on these enzymes is thin.

Protease should be avoided during pregnancy unless your doctor prescribes it; lipase and lactase have limited pregnancy data, so talk to your doctor first. During breastfeeding, there's little data on any of them — ask your healthcare provider before using regularly.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we weren't able to verify several of the enzymes in this blend, so use the medication checker on this page with your exact drugs to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

DGST is a straightforward enzyme blend for people who want digestive support, especially if you're lactose intolerant. If you have inflammatory bowel disease or chronic digestive problems, check with your doctor first.

No drug interactions are documented, but run your medications through the tool below to be thorough. Pregnant or nursing?

Talk to your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DGST, straight from the product label.

Brand Loomis Enzymes
Barcode (UPC) 697706042009
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 327427
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DGST by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
697706042009
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Hemicellulase0 NP--
Proprietary Enzyme Blend244 mg--
Diastase0 NP--

Other ingredients: Phytase, Cellulose, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

pHBS pH Balancing System

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children

Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Do not use if inner or outer seal is broken, torn, or missing.

Storage

To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.

FDA Statement of Identity

A Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for use: Take 2 capsules, 3 times daily with meals or as directed.

See for yourself

DGST by Loomis Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DGST by Loomis Enzymes

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

244 mg per serving
  • › Amylase
  • Protease
  • Lipase
  • Lactase
  • › Cellulase
  • › Invertase
  • › Glucoamylase
  • › Hemicellulase
  • › Diastase

Other (inactive) ingredients: Phytase, Cellulose, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

DGST by Loomis Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in DGST. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for DGST, from the product label.

Loomis Enzymes

See all Loomis Enzymes products
Name
Loomis Enzymes, LLC
City
Fitchburg
State
Wisconsin
ZipCode
53719
Phone Number
1-800-614-4400
Web Address
www.loomisenzymes.com
Pharmacist Counseling Corner

DGST by Loomis Enzymes: Common Questions

Does DGST by Loomis Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in DGST. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
DGST contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase in this product actually help with lactose intolerance?
Yes — lactase is rated effective for lactose intolerance. If you have trouble digesting milk products, this enzyme can help break down that sugar so your body can handle dairy better.
Are digestive enzymes safe for most people?
Protease, lipase, and lactase are generally well tolerated in adults. Some people report mild digestive upset, and very rarely, allergic reactions occur. If you have a serious digestive condition, check with your doctor first.
Is it safe to take DGST during pregnancy?
The safety data is limited. Protease should be avoided during pregnancy unless prescribed; lipase and lactase have insufficient data, so ask your doctor before using regularly. There isn't enough information to say either way without personalized advice.
Can I take this while breastfeeding?
There's little safety data on these enzymes during breastfeeding. Check with your healthcare provider before regular use — they can weigh the benefits for your situation.
Will DGST help with bloating or upset stomach?
The evidence for digestive enzymes on upset stomach or bloating isn't established yet. Lactase does work for lactose intolerance specifically, but the other enzymes' effectiveness for general digestive complaints isn't clear from the research we have.
Does this product have any fillers?
Yes — it contains phytase, cellulose, and water as inactive ingredients. These are typical capsule materials and binders.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DGST is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DGST label
Sources

Sources & How We Checked

DGST's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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