Digestive Enzymes Ingredients & Drug Interactions
by Klaire Labs
What is this page for?
First and foremost: checking Digestive Enzymes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Digestive Enzymes is a dietary supplement by Klaire Labs with 5 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Digestive Enzymes by Klaire Labs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Klaire Labs Digestive Enzymes contains 5 active ingredients: Amylase, Lipase, Lactase, Cellulase, and Neutral Protease. These are enzymes — proteins that break down different parts of food.
Amylase tackles carbohydrates, Lipase handles fats, Lactase breaks down milk sugar, Cellulase breaks down plant fiber, and Neutral Protease breaks down proteins. The product also contains inactive ingredients (Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, and Water) that help form and deliver the capsule.
Does it work?
Strong evidence
The evidence for digestive enzymes in this product is limited. Lactase is effective for lactose intolerance.
For the others — Lipase for inflammatory bowel disease (IBD) and dyspepsia (indigestion), and Neutral Protease — the data we hold doesn't establish whether they work. The evidence for Neutral Protease hasn't been rated in our data.
How safe is it?
Well-documented data
Lipase, Lactase, and Neutral Protease are generally well tolerated in adults, though digestive upset or allergic reactions are possible, especially with the protease. A rare allergy to powdered lactase has been reported in occupational exposure.
Neutral Protease should be avoided in pregnancy unless prescribed — safety hasn't been established. For Lipase and Lactase in pregnancy, the data is thin; check with your doctor.
Neither should be used during breastfeeding without medical guidance. People with serious digestive conditions should use Lipase only under medical supervision.
We don't hold safety data for Amylase or Cellulase.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This product is mainly useful if you have lactose intolerance — Lactase is effective for that. If you have IBD or chronic indigestion, the evidence for Lipase isn't strong enough to know if it'll help.
Talk to your pharmacist or doctor before starting, especially if you're pregnant, breastfeeding, or have a serious digestive condition.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Digestive Enzymes, straight from the product label.
| Brand | Klaire Labs |
|---|---|
| Barcode (UPC) | 817234011890 |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 21, 2024 |
| DSLD ID | 322269 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Digestive Enzymes by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Neutral Protease | 0 NP | -- |
| Digestive Enzyme Blend | 50 mg | -- |
Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Free of following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, and peanuts. Contains no artificial colors, flavors, or preservatives.
Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.
Suggested/Recommended/Usage/Directions
Suggested use: 1 capsule with each meal or as directed by a healthcare professional.
General Statements
Units are those used in the Food Chemicals Codex (FCC)
SFI
Precautions
Do not use if shrinkwrap is broken or missing.
Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your physician before using this product.
Keep out of reach of children.
Storage
Store in a cool, dry place (59 degree F - 85 degrees F) away from direct light.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Digestive Enzymes by Klaire Labs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Digestive Enzymes by Klaire Labs
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Digestive Enzyme Blend
- › Amylase
- › Lipase
- › Lactase
- › Cellulase
- › Neutral Protease
Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Water. These complete the product’s ingredient list but are not active constituents.
Digestive Enzymes by Klaire Labs Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Digestive Enzymes. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Digestive Enzymes, from the product label.
Klaire Labs
See all Klaire Labs products- Name
- SFI USA
- City
- Reno
- State
- NV
- ZipCode
- 89521
- Web Address
- Klaire.com
Digestive Enzymes by Klaire Labs: Common Questions
Does Digestive Enzymes by Klaire Labs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this good for lactose intolerance?
Can I take this for indigestion or inflammatory bowel disease?
Is it safe to take if I'm pregnant?
Can I take it while breastfeeding?
What does the Digestive Enzyme Blend ingredient do?
Are there any fillers in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Digestive Enzymes is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Digestive Enzymes’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Digestive Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC