No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 19 ingredients. Check your meds →
Dietary supplement

Vital-Zymes Chewable Ingredients & Drug Interactions

by Klaire Labs

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Vital-Zymes Chewable is a dietary supplement by Klaire Labs with 19 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Vital-Zymes Chewable by Klaire Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 19 active ingredients.
  • “Fat Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Protein and Peptide Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Carbohydrate Specific Enzymes” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Vital-Zymes Chewable contains 19 ingredients, most of them digestive enzymes that break down food in different ways. You've got lipase (which breaks down fats), lactase (which helps digest milk sugar), acid protease and alkaline protease (which break down proteins), and phytase (which helps with mineral absorption).

The blend also includes several carbohydrate-digesting enzymes like amylase, sucrase, and maltase, plus some you may not recognize—like serratia peptidase and enzymes in proprietary blends that work on various plant fibers and starches. The inactive ingredients are xylitol, mannitol, stearic acid, silicon dioxide, and natural cherry flavor—basically the stuff that makes it chewable and taste decent.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Comprehensive digestive enzyme support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating and gas.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence on most of these enzymes is thin. Lactase is the one backed by solid research—it's effective for lactose intolerance, which is why it's in here.

For lipase, phytase, and the proteases, the data we hold shows insufficient reliable evidence to rate them for any condition. The other enzymes in the blend don't have effectiveness ratings in our records either.

That doesn't mean they don't work; it means the research to prove it isn't established in the sources we follow.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases) Lactase Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The enzymes in this product are generally well tolerated in adults. No adverse effects have been reported in adults for lipase or lactase.

The proteases (acid protease and alkaline protease) may occasionally cause digestive upset or allergic reactions in sensitive people, and there are rare case reports of allergic reactions to inhaled protease dust in workers—but that's from occupational exposure, not from taking a chewable tablet. Phytase has similar rare allergy reports from occupational exposure in the animal-feed industry, not from supplement use.

For pregnancy, the data is spotty. Lactase is likely safe to use during pregnancy.

Lipase, phytase, and the proteases all have limited or no pregnancy data—the safety notes advise checking with your doctor before regular use. For breastfeeding, there's not enough data on any of these to know either way; talk with your healthcare provider if you're nursing and want to take this.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases) Lactase Phytase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, use the medication checker below before you start, especially if you take any regular prescriptions.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a broad-spectrum digestive enzyme blend—useful if you have trouble breaking down food or feel bloated after meals, especially if lactose is an issue. If you have serious digestive conditions or are pregnant or breastfeeding, clear it with your doctor first.

No medication interactions are documented for the ingredients we could check, but run your exact prescriptions through the tool on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 19 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vital-Zymes Chewable, straight from the product label.

Brand Klaire Labs
Barcode (UPC) 709616012185
Net contents 180 Chewable Tablet(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 281271
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vital-Zymes Chewable by Klaire Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
90
UPC/BARCODE
709616012185
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Alpha-Galactosidase0 NP--
Maltase0 NP--
Acid Protease0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Alpha-Amylase0 NP--
Sucrase0 NP--
Alkaline Protease0 NP--
Pullulanase0 NP--
Galactomannase0 NP--
Fat Specific Enzymes0 NP--
Protein and Peptide Specific Enzymes0 NP--
Protease/Peptidase Complex0 NP--
Serratia Peptidase0 NP--
Hemicellulase/Pectinase/Phytase Complex0 NP--
Carbohydrate Specific Enzymes0 NP--
Sugar Specific Enzymes0 NP--
Vegetable/Plant Fiber Specific Enzymes0 NP--
Comprehensive Enzyme Blend320 mg--
Glucoamylase0 NP--

Other ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, natural Cherry flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Comprehensive Enzyme Supplement

Brand IP Statement(s)

Klaire Labs is a division of: ProThera, Inc

Formulation

Free of the following common allergens: Milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.

All ingredients are of the highest quality and purity available. Formulated for the most sensitive individual.

Suggested/Recommended/Usage/Directions

Suggested Use: 2 tablets daily with each meal or as directed by a healthcare practitioner.

Precautions

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Storage

Store in a cool, dry place (59 degrees F - 85 degrees F) away from direct light.

See for yourself

Vital-Zymes Chewable by Klaire Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vital-Zymes Chewable by Klaire Labs

These are the 19 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fat Specific Enzymes

0 NP per serving

Protein and Peptide Specific Enzymes

0 NP per serving

Serratia Peptidase

0 NP per serving

Carbohydrate Specific Enzymes

0 NP per serving
  • › Amylase
  • › Alpha-Amylase
  • › Glucoamylase

Sugar Specific Enzymes

0 NP per serving
  • Lactase
  • › Maltase
  • › Sucrase
  • › Pullulanase

Vegetable/Plant Fiber Specific Enzymes

0 NP per serving
  • › Cellulase
  • › Alpha-Galactosidase
  • › Beta-Glucanase
  • Phytase
  • › Galactomannase
  • › Hemicellulase/Pectinase/Phytase Complex

Comprehensive Enzyme Blend

320 mg per serving

Other (inactive) ingredients: Xylitol, Mannitol, Stearic Acid, Silicon Dioxide, Natural Cherry flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vital-Zymes Chewable by Klaire Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Vital-Zymes Chewable. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Vital-Zymes Chewable, from the product label.

Klaire Labs

See all Klaire Labs products
Name
ProThera Inc.
City
Reno
State
NV
ZipCode
89521
Phone Number
888-488-2488
Pharmacist Counseling Corner

Vital-Zymes Chewable by Klaire Labs: Common Questions

Does Vital-Zymes Chewable by Klaire Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Vital-Zymes Chewable. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Vital-Zymes Chewable contains 19 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me digest food better if I have a sensitive stomach?
It's designed to help break down fats, proteins, and carbs. Lactase specifically works well for milk digestion. But if you have a serious digestive condition, you should use enzymes only under medical guidance—check with your doctor first.
Is it safe to take if I'm pregnant?
Lactase is likely safe in pregnancy. For the other enzymes—lipase, phytase, and the proteases—there isn't enough safety data to know either way. Talk with your doctor or pharmacist for personalized advice before using it regularly during pregnancy.
Can I take this while breastfeeding?
Safety data while breastfeeding hasn't been well studied for most of these enzymes. Check with your healthcare provider first to be safe.
What does 'chewable' mean—does that change how it works?
Chewable just means you can bite it up rather than swallow a capsule whole. The enzymes still do their job in your digestive tract once you've chewed and swallowed it.
Are there any fillers or stuff I should know about?
The inactive ingredients are xylitol, mannitol, stearic acid, silicon dioxide, and natural cherry flavor. Those are pretty standard for a chewable tablet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vital-Zymes Chewable is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vital-Zymes Chewable label
Sources

Sources & How We Checked

Vital-Zymes Chewable's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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