DigestPlus Ingredients & Drug Interactions
What is this page for?
First and foremost: checking DigestPlus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
DigestPlus is a dietary supplement by EvinceNaturals with 7 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of DigestPlus by EvinceNaturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
DigestPlus contains 7 active enzyme ingredients designed to support digestion. Protease breaks down proteins, Lipase (from fungal sources) handles fats, and Lactase helps with lactose digestion.
Amylase, Cellulase, Invertase, and Diastase round out the blend to work on carbohydrates and fiber. The capsules also contain inactive ingredients: beet juice powder, gelatin, magnesium stearate, and silica.
Does it work?
Strong evidence
The evidence we have is limited. Lactase is rated effective for lactose intolerance — if you have trouble digesting dairy, this ingredient may help.
For the other enzymes in the blend — Protease, Fungal Lipase, and the rest — the data shows insufficient reliable evidence to rate their effectiveness for digestive complaints. That doesn't mean they don't work; it means large, rigorous trials backing them up haven't been done yet.
How safe is it?
Well-documented data
Protease, Lactase, and Fungal Lipase are generally well tolerated in most adults, though some people report mild digestive upset. Rarely, occupational or airborne exposure to proteolytic enzymes has caused allergic reactions like nasal or eye irritation or asthma; that's uncommon outside factory settings, but it's on the record.
If you have a serious digestive condition like inflammatory bowel disease, check with your doctor before using Fungal Lipase. For pregnancy and breastfeeding, there isn't enough safety data on most of these enzymes — talk with your doctor or pharmacist before taking this product if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we were able to check in DigestPlus.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
DigestPlus is a multi-enzyme supplement that may help if you have lactose intolerance, though evidence for the other ingredients isn't well established. It doesn't interact with medications we can check.
If you're pregnant, breastfeeding, or have a chronic digestive condition, chat with your doctor or pharmacist before starting it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about DigestPlus, straight from the product label.
| Brand | EvinceNaturals |
|---|---|
| Barcode (UPC) | 094922842350 |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 229502 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for DigestPlus by EvinceNaturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Diastase | 0 NP | -- |
| Lipase, Fungal | 0 NP | -- |
| Enzyme Proprietary Blend | 371 mg | -- |
Other ingredients: Beet juice powder, Gelatin, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommended use: Two capsules with every meal. More capsules may be taken as needed. The amount is dependent on the types and amounts of foods eaten and the individual's difficulty of digestion.
Precautions
Keep out of reach of children.
Do not use if plastic cap or printed inner seal is broken or missing.
Storage
Store in cool, dry place.
Formulation
DigestPlus is uniquely formulated to assist the body in maximum digestion of nutrients, the production of energy, and aid in immune support. The highly purified enzymes in DigestPlus are concentrated from mycological sources specifically cultivated for optimum digestive activity in the human body.
Enzyme activity is measured in Food Chemical Codex (FCC) units.
General Statements
Unlocking nature's power
Reorder by calling toll free: 1-800-676-5510
Formula
With live plant enzymes
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
DigestPlus by EvinceNaturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in DigestPlus by EvinceNaturals
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Enzyme Proprietary Blend
- › Amylase
- › Protease
- › Lactase
- › Cellulase
- › Invertase
- › Diastase
- › Lipase, Fungal
Other (inactive) ingredients: Beet juice powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
DigestPlus by EvinceNaturals Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in DigestPlus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for DigestPlus, from the product label.
EvinceNaturals
See all EvinceNaturals products- Name
- EvinceNaturals
- City
- North Salt Lake
- State
- Utah
- ZipCode
- 84054
- Phone Number
- 1-800-676-5510
- Web Address
- www.evincenaturals.com
DigestPlus by EvinceNaturals: Common Questions
Does DigestPlus by EvinceNaturals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will DigestPlus help with lactose intolerance?
Is protease safe?
Can I take this while pregnant?
Is it safe to breastfeed while taking DigestPlus?
Does DigestPlus interact with any of my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if DigestPlus is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind DigestPlus’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
DigestPlus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC