No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

En-Zym Gest Ingredients & Drug Interactions

by Foster Regal

Tablet Or Pill Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

En-Zym Gest is a dietary supplement by Foster Regal with 5 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of En-Zym Gest by Foster Regal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Pancreatin 4X” is listed as a grouped ingredient — the label gives one combined amount (100 mg) without saying how much of each component you get.

En-Zym Gest contains 5 active ingredients: protease, lipase, amylase, cellulase, and pancreatin 4X, along with bile extract. These are digestive enzymes—proteins your body normally makes to break down food in your stomach and small intestine.

Protease breaks down protein, lipase handles fat, amylase tackles carbohydrates, and cellulase works on plant fiber. Pancreatin is a blend of multiple enzymes from animal pancreas, and bile extract supports fat digestion.

The tablet also contains inactive ingredients like calcium phosphate, vegetable stearic acid, vegetable cellulose, silica, riboflavin, and vanillin—the binders, fillers, and flavoring that hold the tablet together and keep it stable.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Digestive enzyme support with meals.
  • We looked for evidence on: Dyspepsia, Indigestion, Bloating, Fat digestion.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence for these enzymes is limited. For lipase specifically, the data we hold shows insufficient reliable evidence to rate it for inflammatory bowel disease (IBD), dyspepsia (indigestion), or prematurity.

We don't have effectiveness ratings on file for protease, amylase, cellulase, or pancreatin 4X. That means the research backing their use in supplements isn't well established in the sources we check.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated in adults, though digestive upset or allergic reactions can happen rarely. Protease is used in laundry detergents, and in rare cases people exposed to airborne protease (mainly through occupational contact) have developed allergic rhinitis or asthma—but that's from inhaling it, not swallowing a tablet.

No adverse effects have been reported in adults taking lipase supplements, though thorough safety studies haven't been done. For pregnancy, protease safety hasn't been established and is best avoided unless prescribed.

Lipase also has little safety data in pregnancy—use only if your doctor advises it. Neither ingredient has been well studied during breastfeeding; check with your healthcare provider first.

We don't have safety data on file for amylase, cellulase, or bile extract.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we were able to check. That said, we couldn't review amylase, cellulase, or bile extract—so if you take prescription medications, plug them into the checker on this page to be thorough.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

En-Zym Gest is a straightforward digestive enzyme blend for people looking to support their digestion. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting—the safety data is thin.

Anyone with serious digestive conditions should get medical guidance before using it. No drug interactions are documented for the ingredients we checked.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about En-Zym Gest, straight from the product label.

Brand Foster Regal
Barcode (UPC) 364175298908
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261107
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for En-Zym Gest by Foster Regal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
90
UPC/BARCODE
364175298908
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Cellulase2 mg--
Pancreatin 4X100 mg--
Bile extract50 mg--

Other ingredients: Calcium Phosphate, Vegetable Stearic Acid, Vegetable Cellulose, Silica, Riboflavin, Vanillin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a food enzyme dietary supplement, take 1 tablet with each meal and if necessary at bedtime. Don't hesitate to use two servings (2 tablets) with each meal and at bedtime if needed.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing, consult your physician before taking this product.

Contains milk ingredients.

Formula

Mfg. in a Ko Kosher Certified, FDA Registered Facility using Good Manufacturing Practices (GMPs)

Pancreatic enzyme concentrate containing amylase, protease lipase with cellulase and bile extract

Formulation

Mfg. in a Ko Kosher Certified, FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Made in USA

Gluten free

Nutritionally supports digestive health

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Foster Regal The best choice.

FDA Statement of Identity

Food Enzyme Dietary Supplement

See for yourself

En-Zym Gest by Foster Regal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in En-Zym Gest by Foster Regal

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Cellulase

2 mg per serving

Pancreatin 4X

100 mg per serving

Bile extract

50 mg per serving

Other (inactive) ingredients: Calcium Phosphate, Vegetable Stearic Acid, Vegetable Cellulose, Silica, Riboflavin, Vanillin. These complete the product’s ingredient list but are not active constituents.

Interaction report

En-Zym Gest by Foster Regal Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in En-Zym Gest. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for En-Zym Gest, from the product label.

Foster Regal

See all Foster Regal products
Name
Foster Regal Laboratories
Street Address
115 S.C.T. Ct.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

En-Zym Gest by Foster Regal: Common Questions

Does En-Zym Gest by Foster Regal interact with any medications?
We do not currently list a known interaction for the mapped ingredients in En-Zym Gest. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
En-Zym Gest contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
Protease in this product hasn't been tested enough in pregnancy and is best avoided unless your doctor prescribes it. Lipase also has very little safety data during pregnancy—only use it if your doctor advises you to. Talk with your healthcare provider about whether En-Zym Gest is right for you.
Is it safe to breastfeed while taking this?
Safety data during breastfeeding is thin for both protease and lipase. Check with your healthcare provider before using this product while nursing.
What are the side effects?
Digestive upset or allergic reactions are rare but possible with protease. No adverse effects have been reported in adults taking lipase in supplement form, though a thorough safety review hasn't been completed. If you have a serious digestive condition, use this product only under medical guidance.
Does this actually work for digestion?
The evidence for these enzymes is limited. We don't have strong effectiveness data on file for most of the ingredients—including protease, amylase, and cellulase. Lipase shows insufficient reliable evidence for conditions like indigestion or inflammatory bowel disease.
What is protease in this product?
Protease is a digestive enzyme that breaks down protein into smaller pieces your body can absorb. It's naturally made in your stomach and pancreas.
Can people with serious digestive conditions take this?
If you have inflammatory bowel disease, chronic pancreatitis, or another serious digestive condition, use En-Zym Gest only under your doctor's guidance. These conditions need individual attention.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if En-Zym Gest is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

En-Zym Gest label
Sources

Sources & How We Checked

En-Zym Gest's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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