No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 10 ingredients. Check your meds →
Dietary supplement

Enzymes For Kids Orange-Flavored Ingredients & Drug Interactions

by Natural Enzymes

Powder Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Enzymes For Kids Orange-Flavored is a dietary supplement by Natural Enzymes with 10 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Enzymes For Kids Orange-Flavored by Natural Enzymes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (83.70 mg) without saying how much of each component you get.

This powder contains 8 active enzymes designed to support digestion in kids. Protease breaks down proteins, lipase handles fats, and lactase helps with milk sugar digestion — all three have established monographs.

Amylase, glucoamylase, invertase, cellulase, and maltase round out a proprietary enzyme blend meant to work on different carbohydrates and starches. The inactive ingredients are fructose, natural flavors, citric acid, and annatto (a natural colorant).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive enzyme support for children.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, indigestion, bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase in this product is effective for lactose intolerance — that's solid evidence. For the other enzymes — protease, lipase, and the rest — we don't have enough reliable data to rate how well they work for digestive support in kids.

The research just isn't established in our system yet.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated, though some children may have digestive upset or, rarely, allergic reactions. Lactase is generally well tolerated when used as directed.

In rare cases, people exposed to powdered lactase have developed contact allergies or breathing problems, though this is unusual. For pregnancy: protease is best avoided unless prescribed.

Lipase and lactase both have limited pregnancy data — if you're pregnant and considering this for yourself, check with your doctor. For breastfeeding: protease and lipase have little safety data and need medical advice first; lactase is likely safe but ask your pharmacist.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check in this product.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is designed for kids with digestive challenges, especially those who struggle with milk sugar (lactose intolerance) — that's where the evidence is strongest. If your child has serious digestive conditions, run it by their doctor first.

Check with your child's doctor or pharmacist before starting, particularly if they're on any medications or have known enzyme allergies.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 23, 2011.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Enzymes For Kids Orange-Flavored, straight from the product label.

Brand Natural Enzymes
Barcode (UPC) 697706066005
Net contents 11.11 oz.; 315 Gram(s)
Market status On market
Date entered into DSLD Dec 23, 2011
DSLD ID 3112
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Gluten Free, Dairy Free, Sugar Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Enzymes For Kids Orange-Flavored by Natural Enzymes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 tsp
Maximum serving Sizes:
1 tsp
Servings per container
63
UPC/BARCODE
697706066005
IngredientAmount% DV
Calories20 {Calories}--
Total Carbohydrates5 g2%
Sugar5 g--
Protein1 g--
Amylase0 NP--
Protease0 NP--
Glucoamylase0 NP--
Invertase0 NP--
Lipase0 NP--
Lactase0 NP--
Proprietary Enzyme Blend83.7 mg--
Cellulase0 NP--
Maltase0 NP--

Other ingredients: Fructose, Natural Flavors, Citric Acid, Annatto

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Do not use if inner or outer seal is broken, torn, or missing.

Note: Do not use if you are pregnant or nursing except on the advice of a health care practitioner. As with any dietary supplement, consult your physician before taking this product if you have any medical condition or if you are currently taking prescription medication.

Storage

To ensure freshness and potency, keep bottle tightly closed and store in a cool dry place.

General Statements

Great-tasting

FDA Statement of Identity

Powdered Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Usage: Take 1 teaspoon, mixed with water, 3 times daily before each meal.

Brand IP Statement(s)

pHBS pH Balancing System

EFI Enzyme Formulations, Inc.

Formulation

Contains no added fillers, lubricants, soy, wheat, corn, dairy, sugar, yeast, gluten, starch, salt, additives, or preservatives.

See for yourself

Enzymes For Kids Orange-Flavored by Natural Enzymes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Enzymes For Kids Orange-Flavored by Natural Enzymes

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 tsp Dosage formPowder Servings per container63 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

5 g per serving

Protein

1 g per serving

Proprietary Enzyme Blend

83.7 mg per serving
  • › Amylase
  • › Protease
  • › Glucoamylase
  • › Invertase
  • › Lipase
  • › Lactase
  • › Cellulase
  • › Maltase

Other (inactive) ingredients: Fructose, Natural Flavors, Citric Acid, Annatto. These complete the product’s ingredient list but are not active constituents.

Interaction report

Enzymes For Kids Orange-Flavored by Natural Enzymes Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Enzymes For Kids Orange-Flavored. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Enzymes For Kids Orange-Flavored, from the product label.

Natural Enzymes

See all Natural Enzymes products
Name
Enzyme Formulations, Inc.
City
Madison
State
Wisconsin
ZipCode
53719
Web Address
www.enzymeformulations.com
Pharmacist Counseling Corner

Enzymes For Kids Orange-Flavored by Natural Enzymes: Common Questions

Does Enzymes For Kids Orange-Flavored by Natural Enzymes interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Enzymes For Kids Orange-Flavored. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Enzymes For Kids Orange-Flavored contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe for my young child?
Yes — the enzymes here (protease, lipase, lactase) are generally well tolerated in kids. That said, rarely, some children may have digestive upset or allergic reactions. If your child has serious digestive problems or a known enzyme allergy, talk with their pediatrician first.
Will this help my child's lactose intolerance?
Lactase is effective for lactose intolerance, and it's one of the main enzymes in this product. For the other enzymes — protease, lipase, and the rest — we don't have strong evidence yet for how well they work in kids.
What does protease do?
Protease is an enzyme that breaks down proteins during digestion. It's generally well tolerated, though rarely it can cause digestive upset or allergic reactions.
Can I give this to my child if they're on medication?
We haven't documented any interactions between the enzymes in this product and medications. Still, it's smart to check with your child's doctor or pharmacist before adding any new supplement, just to be sure it's right for them.
What's the proprietary enzyme blend?
It's a mix of enzymes that work on different carbohydrates and starches — cellulase, maltase, and others are listed on the label. We don't have enough data to rate how well they work on their own.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Enzymes For Kids Orange-Flavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Enzymes For Kids Orange-Flavored label
Sources

Sources & How We Checked

Enzymes For Kids Orange-Flavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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