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Dietary supplement

Essential Supplement Ingredients & Drug Interactions

by BioAnue

Essential Supplement label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Essential Supplement against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Essential Supplement is a dietary supplement by BioAnue with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Liver Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Essential Supplement by BioAnue

Ask about any prescription or over-the-counter medication and we check it for interactions with Essential Supplement by BioAnue — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Essential Supplement by BioAnue

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

BioAnue's Essential Supplement contains one active ingredient: liver extract, a whole-food derivative used traditionally to support energy and liver health. The capsule itself is made from gelatin, an inactive ingredient that serves as the container.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for liver extract is limited. For chronic fatigue syndrome, the data shows it is possibly ineffective — meaning current evidence does not support its use for that condition.

For hepatitis C, we simply don't have enough reliable evidence to rate whether it works. If you're considering this supplement for a specific health concern, talk with your doctor about what the science actually shows.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been formally reported, but a thorough safety evaluation hasn't been completed. The bigger concern is source quality: liver extract comes from raw animal liver obtained at slaughterhouses, and there's a risk of contamination from sick or diseased animals.

Additionally, some liver extracts from countries where bovine spongiform encephalitis (BSE, a fatal brain disease in cattle) has been reported — including Great Britain, France, The Netherlands, Portugal, Luxembourg, Ireland, Switzerland, Oman, and Belgium — carry a theoretical contamination risk, though no human cases from liver extract have been documented so far. Liver extract can also deliver very high levels of vitamin A and iron.

High vitamin A in pregnancy may harm a developing baby, so pregnant people should avoid it unless their doctor advises otherwise. Because safety hasn't been well studied overall, talk with your doctor before using this product.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) for blood clotting, or iron supplements or iron-containing medications, check with your doctor or pharmacist before starting this product. Both interactions are Minor, but they're worth confirming with your own provider before you add it in.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

BioAnue's Essential Supplement is a single-ingredient product with limited evidence for its intended uses and real concerns about product sourcing and contamination risk. If you take warfarin or iron supplements, you'll want to check with your pharmacist or doctor first.

Pregnant people should avoid it unless their doctor says it's okay. Before you start, run it through with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Essential Supplement, straight from the product label.

Brand BioAnue
Net contents 180 Capsule(s); 850 mg
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 27151
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Essential Supplement by BioAnue, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
IngredientAmount% DV
Liver Extract850 mg--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Your Edge - Your New Beginning

Suggested/Recommended/Usage/Directions

Usage: As a dietary supplement consume one (1) capsule per day, or as directed by a health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Essential Supplement by BioAnue label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Essential Supplement label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Essential Supplement by BioAnue

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Liver Extract

Interacts with
3 drugs
850 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Liver Extract monograph & interactions

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Essential Supplement by BioAnue Drug Interactions

Want to check YOUR meds against Essential Supplement?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Liver Extract 3

Individual Drug Interactions

The ingredients in Essential Supplement interact with 3 drugs. Click any drug to see the details.

1 of the 1 ingredient in Essential Supplement interact with drugs. Each result below shows which ingredient is responsible. Liver Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Essential Supplement with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Liver Extract2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
Liver Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Essential Supplement, from the product label.

BioAnue

See all BioAnue products
Name
BioAnue Laboratories Inc.
Street Address
P.O. Box 1056, 123 Wood Tech Dr.
City
Rochelle
State
GA
ZipCode
31079
Pharmacist Counseling Corner

Essential Supplement by BioAnue: Common Questions

Does Essential Supplement by BioAnue interact with any medications?
Yes. Based on its ingredients, Essential Supplement has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Essential Supplement contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Liver extract can contain very high levels of vitamin A, which may harm a developing baby. The safety data advises against use during pregnancy unless your doctor specifically tells you it's okay. For breastfeeding, there isn't enough safety data on file — talk with your doctor or pharmacist to decide what's right for you.
Does liver extract actually work for chronic fatigue?
The current evidence says it's possibly ineffective for chronic fatigue syndrome — meaning studies don't support using it for that condition. If you're dealing with chronic fatigue, your doctor can discuss options with better evidence behind them.
What are the main risks I should know about?
The biggest concerns are contamination risk (liver extract comes from raw animal livers at slaughterhouses, with a theoretical risk from BSE in certain countries) and the fact that it delivers very high amounts of vitamin A and iron. If you have an iron-overload disorder like hemochromatosis, this product isn't a good fit. Check the source country on the label if you can, and talk with your doctor about whether it's right for you.
What's in the capsule besides the liver extract?
The capsule itself is made from gelatin, which is an inactive ingredient — just the container. The active ingredient is the liver extract.
Can I take this with warfarin?
Liver extract may contain small amounts of vitamin K, which could theoretically reduce how warfarin works, but this hasn't been directly studied in humans. Because you're on a blood thinner, you should check with your pharmacist or doctor before starting — they can advise you on whether it's safe in your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Essential Supplement is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Essential Supplement label
Go deeper

The Full Monographs Behind Essential Supplement’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph →
Sources

Sources & How We Checked

Essential Supplement's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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