Fat DigestEnz Ingredients & Drug Interactions
by ProEnzol
What is this page for?
First and foremost: checking Fat DigestEnz against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fat DigestEnz is a dietary supplement by ProEnzol with 7 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Fat DigestEnz by ProEnzol
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Fat DigestEnz is a digestive enzyme blend with 7 active ingredients. Lipase breaks down dietary fats; proteases break down proteins; amylase breaks down carbohydrates; and the others — cellulase, peptidase, glucoamylase, and alpha-galactosidase — help break down plant fibers and complex sugars.
The product also contains plant fiber and water as inactive ingredients.
Does it work?
Not established
The evidence for these enzymes is limited. Lipase is rated as having insufficient reliable evidence for inflammatory bowel disease (IBD) and dyspepsia (indigestion).
Proteases have no effectiveness ratings on file. In general, digestive enzyme supplements are studied far less than prescription medications, so we don't have strong data to say whether this blend will work for any specific condition.
How safe is it?
Well-documented data
Lipase is generally well tolerated in supplement form, though people with serious digestive conditions should use it only under medical guidance. Proteases are also generally well tolerated for most adults but may cause digestive upset or allergic reactions in some people.
There is little safety data on lipase in pregnancy or while breastfeeding — check with your healthcare provider before taking it if you're pregnant or nursing. Proteases are best avoided during pregnancy unless prescribed by your doctor.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. Before starting, run your exact medications through the checker on this page or confirm with your pharmacist.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This enzyme blend is generally well tolerated and carries no documented drug interactions we can find. If you have serious digestive problems, are pregnant, breastfeeding, or take any medications, talk it over with your doctor or pharmacist first — they can help you figure out whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fat DigestEnz, straight from the product label.
| Brand | ProEnzol |
|---|---|
| Barcode (UPC) | 707636123010 |
| Net contents | 90 Vegan Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2020 |
| DSLD ID | 221309 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fat DigestEnz by ProEnzol, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Peptidase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Fat DigestEnz Blend | 335 mg | -- |
| Proteases | 0 NP | -- |
Other ingredients: Plant Fiber, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
ProEnzol Fat DigestEnz provides a blend of non-animal derived enzymes with extra Lipase to assist the body's own enzymes in the digestion of high-fat foods and assimilation of fat-soluble nutrients, helping to relieve occasional gastrointestinal discomfort associated with an inability to properly break down fat.
Formulation
ProEnzol Fat DigestEnz provides a blend of non-animal derived enzymes with extra Lipase to assist the body's own enzymes in the digestion of high-fat foods and assimilation of fat-soluble nutrients, helping to relieve occasional gastrointestinal discomfort associated with an inability to properly break down fat.
Helps digest high-fat foods and assimilate fat-soluble nutrients
Contains no: sugar, soy, wheat, yeast, gluten, peanuts, tree nuts, eggs, dairy, animal products, artificial colors, flavors and sweeteners or genetically modified organisms (GMOs).
Suggested/Recommended/Usage/Directions
Directions: Take one (1) capsule 20 minutes after each meal or snack containing fat, or as directed by your healthcare professional.
Precautions
Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your healthcare professional before use.
Use only if tamper-evident seal is unbroken.
Keep out of reach of children.
Storage
Store tightly closed in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, mitigate, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Exclusively for professionals
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fat DigestEnz by ProEnzol label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fat DigestEnz by ProEnzol
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Plant Fiber, Water. These complete the product’s ingredient list but are not active constituents.
Fat DigestEnz by ProEnzol Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Fat DigestEnz. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Fat DigestEnz, from the product label.
ProEnzol
See all ProEnzol products- Name
- Enzymes Inc.
- City
- Kansas City
- State
- MO
- ZipCode
- 64153
- Phone Number
- 1-800-637-7893
- Web Address
- www.proenzol.com
Fat DigestEnz by ProEnzol: Common Questions
Does Fat DigestEnz by ProEnzol interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with indigestion?
Can I take this if I have inflammatory bowel disease?
Is it safe to take while pregnant?
Is it safe while breastfeeding?
What are these enzymes actually for?
Can this cause allergic reactions?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fat DigestEnz is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fat DigestEnz’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Fat DigestEnz's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC