FenuLife Ingredients & Drug Interactions
What is this page for?
First and foremost: checking FenuLife against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
FenuLife is a dietary supplement by Wonder Laboratories with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are deodorized Fenugreek Fiber extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against FenuLife by Wonder Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with FenuLife by Wonder Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of FenuLife by Wonder Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
FenuLife contains one active ingredient: deodorized fenugreek fiber extract. Fenugreek is a plant seed used in traditional medicine and cooking.
The product also contains vegetable cellulose, gelatin, and vegetable magnesium stearate as inactive ingredients (the capsule material and binders).
Does it work?
Moderate evidence
The evidence we hold shows fenugreek is possibly effective for sexual dysfunction and sexual arousal, as well as for menstrual cramps (dysmenorrhea) and blood sugar control in type 2 diabetes. These are modest ratings—they mean there's some research support, but the evidence isn't as strong as for medications.
Talk with your pharmacist or doctor about whether it may help your specific situation.
How safe is it?
Well-documented data
Fenugreek fiber is generally well tolerated when taken in food amounts, but supplement doses can cause side effects. The most common ones are stomach discomfort, bloating, diarrhea, indigestion, gas, and nausea.
Rarely, people have had severe allergic reactions including swelling of the throat, trouble breathing, and shock. Some people also report an unusual body odor after taking fenugreek, which is harmless but can be noticeable.
Avoid medicinal doses during pregnancy—fenugreek may affect the uterus. If you're breastfeeding and want to use fenugreek to boost milk supply, the evidence is limited; talk with your doctor or lactation consultant first before starting.
If you have a history of allergies or asthma, be cautious, as fenugreek can trigger allergic and respiratory symptoms in some people.
Meds to double-check
Moderate interaction found
Before taking FenuLife, double-check with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or clopidogrel), diabetes medications, beta-blockers (like metoprolol), theophylline, phenytoin (an anti-seizure drug), or sildenafil. All of these have documented Moderate interactions with fenugreek that may reduce their effectiveness or increase side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
FenuLife may be worth considering if you're interested in natural support for blood sugar, menstrual cramps, or sexual function and don't take medications that interact with fenugreek. If you're on blood thinners, diabetes medications, heart or blood pressure drugs, seizure medications, or theophylline, you need to check with your pharmacist first.
Pregnant people should avoid medicinal doses. Run your exact medications through our checker before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about FenuLife, straight from the product label.
| Brand | Wonder Laboratories |
|---|---|
| Net contents | 250 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 19, 2021 |
| DSLD ID | 260739 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for FenuLife by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| deodorized Fenugreek Fiber extract | 750 mg | -- |
Other ingredients: Vegetable Cellulose, k-Gelatin, Vegetable Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take two (2) capsules with (8) oz. of water ten to fifteen (10-15) minutes before meals and at bedtime (optional).
Formulation
Highest soluble fiber concentrate means more value. One dose of FenuLife equals three doses of other fenugreek extracts.
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
Deodorized
Use as part of your diet to help maintain a healthy blood sugar level
Gluten free
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Made in USA
Precautions
Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing, consult your physician before taking this product.
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Formula 553
Formula
Fenugreek extract High soluble fiber
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
FenuLife by Wonder Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in FenuLife by Wonder Laboratories
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container125 Amounts shown are per serving.
Deodorized Fenugreek Fiber extract
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Deodorized Fenugreek Fiber extract monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, K-Gelatin, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
FenuLife by Wonder Laboratories Drug Interactions
HelloPharmacist Interaction Report
FenuLife from Wonder Laboratories contains a single active ingredient—deodorized fenugreek fiber extract—that does interact with a number of medications.
The most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs like warfarin and clopidogrel, where fenugreek may increase bleeding risk or alter how the drug works. There's also a Moderate interaction with theophylline (a respiratory medication), where fenugreek may reduce its effectiveness.
Read the full breakdown — every affected drug type, severity by severity
Beyond these, fenugreek can lower blood sugar and may have additive effects with diabetes drugs, raising the risk of low blood sugar (hypoglycemia). It may also lower blood pressure when combined with beta-blockers like metoprolol, and it can interfere with how your body handles phenytoin (an anti-seizure drug) and sildenafil (a medication for erectile dysfunction), potentially reducing their effect.
Altogether, these interactions span 386 individual medications. If you take any prescription medication—especially blood thinners, diabetes drugs, heart or blood pressure medications, seizure drugs, or theophylline—check your exact medications with the search tool on this page before starting FenuLife.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against FenuLife?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in FenuLife interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in FenuLife interact with drugs. Each result below shows which ingredient is responsible. deodorized Fenugreek Fiber extract
Aspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Aspirin, Pentazocine interactionBetrixabanBevyxxa
How Betrixaban interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Betrixaban interactionBivalirudinAngiomax, Angiomax Rtu, Angiox
How Bivalirudin interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Bivalirudin interactionBromfenac SodiumBromsite, Prolensa
How Bromfenac Sodium interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Bromfenac Sodium interactionCabliviCablivi
How Cablivi interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Deodorized Fenugreek Fiber Extract + Cablivi interactionCanagliflozinInvokana
How Canagliflozin interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Deodorized Fenugreek Fiber Extract + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with FenuLife — through 1 ingredient. Tap an ingredient for the detail:
Deodorized Fenugreek Fiber ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Deodorized Fenugreek Fiber Extract + Canagliflozin, Metformin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in FenuLife with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
deodorized Fenugreek Fiber extract
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for FenuLife, from the product label.
Wonder Laboratories
See all Wonder Laboratories products- Name
- Wonder Laboratories
- Street Address
- 115 S.C.T. Ct.
- City
- White House
- State
- TN
- ZipCode
- 37188
FenuLife by Wonder Laboratories: Common Questions
Does FenuLife by Wonder Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
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What are the most common side effects?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if FenuLife is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind FenuLife’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
FenuLife's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
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