No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 4 of 14 ingredients. Check your meds →
Dietary supplement

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 Ingredients & Drug Interactions

by LEAN Nutraceuticals

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 is a dietary supplement by LEAN Nutraceuticals with 14 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 14 active ingredients.
  • “Protein Digestive Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Carbs, Breads, Cereal & Rice Digestive Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Sugars, Dairy & Dessert Digestive Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 14 active ingredients—a mix of individual enzymes and proprietary blends designed to help break down different food components. Lactase splits milk sugar (lactose), lipase breaks down fats, and multiple forms of protease work on proteins.

The blends target carbohydrates and starches (through amylase and glucoamylase), sugars and dairy, fats and seeds, fiber and legumes, and green plants. Phytase and alpha-galactosidase help with plant-based foods.

You'll also find cellulase, hemicellulase, invertase, and beta glucanase to round out carbohydrate digestion. The inactive ingredients—microcrystalline cellulose, rice flour, magnesium stearate, and cellulose—are fillers and binders in the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: aid digestion of carbohydrates and fats.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for these enzymes is mixed. Lactase is effective for lactose intolerance—if you have trouble digesting dairy, this ingredient has solid data behind it.

For the others, the data we hold shows insufficient reliable evidence to rate them: lipase for inflammatory bowel disease (IBD) and indigestion (dyspepsia), protease for any condition listed, and phytase for iron deficiency anemia, zinc deficiency, child growth, aging skin, and blepharospasm. That means we don't have enough studies to say whether they work for those uses—not that they don't work, just that the evidence isn't established in our data.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lactase Lipase Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These enzymes are generally well tolerated when you take them as directed. Lactase, lipase, and the proteases are all commonly used with a good safety record in supplement form.

That said, lipase and phytase come with a caution: if you have serious digestive conditions, use lipase only under medical guidance, and use phytase only if your doctor advises it. Rare allergic reactions have been reported—mostly from occupational exposure to powdered forms of these enzymes (like in industrial settings), including allergic rhinoconjunctivitis, asthma, and hypersensitivity pneumonitis.

Protease carries a small risk of digestive upset. For pregnancy and breastfeeding, the safety data are limited across most ingredients; lactase is likely safe in pregnancy, but lipase, protease, phytase, and several others lack enough data to know either way—talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lactase Lipase Phytase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 4 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That does not mean interactions don't exist—it means our monographs for lactase, lipase, protease, protease 3.0, protease 6.0, and phytase show none.

Before taking this product, have your doctor or pharmacist review your complete medication list to be certain.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

If you're looking to ease lactose digestion, lactase here has solid evidence. For broader enzyme support with other foods, the science is still catching up—the product is generally well tolerated, but we can't confirm it works for the other conditions it may claim to address.

If you have serious digestive issues, check with your doctor or pharmacist first. Same goes if you're pregnant, breastfeeding, or taking any medications—run those specifics by your own healthcare provider before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13, straight from the product label.

Brand LEAN Nutraceuticals
Barcode (UPC) X001KF0QZJ
Net contents 90 Veggie Capsule(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 257345
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
X001KF0QZJ
IngredientAmount% DV
Lactase0 NP--
Lipase0 NP--
Protease0 NP--
Cellulase0 NP--
Hemicellulase0 NP--
Invertase0 NP--
Full Spectrum Digestive Enzyme Blend196 mg--
Protease 3.00 NP--
Protease 6.00 NP--
Alpha-Galactosidase0 NP--
Beta Glucanase0 NP--
Protein Digestive Blend0 NP--
Glucoamylase0 NP--
Amylase0 NP--
Carbs, Breads, Cereal & Rice Digestive Blend0 NP--
Sugars, Dairy & Dessert Digestive Blend0 NP--
Fats & Oil Seeds Digestive Blend0 NP--
Phytase0 NP--
Fiber, Legume & Green Plant Digestive Blend0 NP--

Other ingredients: Microcrystalline Cellulose, Rice Flour, Magnesium Stearate, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1 capsule daily. For best results, take one (1) capsule at the beginning of a meal once daily or as directed by a healthcare professional.

Formulation

LEAN Nutraceuticals Plant-Based Digestive Enzymes PBDE-13 is a scientifically formulated, broad spectrum digestive enzyme supplement. Designed by a Medical Doctor, PBDE-13 includes 13 enzymes that aid in the digestion of carbohydrates, fats and proteins.

GMO Free

Gluten Free 100% Gluten Free

Supports healthy digestion and nutrient uptake Full Spectrum MD-Formulated, Plant-based

Promotes healthy digestion Helps reduce occasional post-meal gas Helps process difficult-to-digest foods Supports proper nutrient uptake

Guarantee 100% natural

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA

GMP Good Manufacturing Practice

General Statements

Recycle

MD-C Medical Doctor Certified

Get the facts @ LeanNutraceuticals.com/PBDE13

FDA Statement of Identity

Dietary Supplement

Formula

Digestive Enzyme - 90-day supply

See for yourself

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals

These are the 14 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Full Spectrum Digestive Enzyme Blend

196 mg per serving

Protein Digestive Blend

0 NP per serving

Carbs, Breads, Cereal & Rice Digestive Blend

0 NP per serving
  • › Beta Glucanase
  • › Glucoamylase
  • › Amylase

Sugars, Dairy & Dessert Digestive Blend

0 NP per serving

Fats & Oil Seeds Digestive Blend

0 NP per serving

Fiber, Legume & Green Plant Digestive Blend

0 NP per serving
  • › Cellulase
  • › Hemicellulase
  • › Alpha-Galactosidase

Other (inactive) ingredients: Microcrystalline Cellulose, Rice Flour, Magnesium Stearate, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13, from the product label.

LEAN Nutraceuticals

See all LEAN Nutraceuticals products
Name
Lean Nutraceuticals
Street Address
902 S. Randall Rd., Suite 300C
City
St. Charles
State
IL
ZipCode
60174
Phone Number
(855) 382-4296
Web Address
www.leannutraceuticals.com
Pharmacist Counseling Corner

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals: Common Questions

Does Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 by LEAN Nutraceuticals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 contains 14 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase actually work for lactose intolerance?
Yes—lactase is rated effective for lactose intolerance. If you have trouble digesting dairy, this ingredient has solid evidence backing it up.
Can I take this if I'm pregnant or breastfeeding?
Lactase is likely safe in pregnancy. For lipase, protease, phytase, and several other ingredients in this blend, there isn't enough safety data to know either way—talk with your doctor or pharmacist to make sure it's right for you.
Are there any side effects I should know about?
These enzymes are generally well tolerated. Protease may cause digestive upset or allergic reactions in some people. Rare allergic reactions to powdered enzyme exposure (like occupational asthma) have been reported, but that's mostly an industrial concern, not a typical supplement user issue.
What's the difference between all the protease forms in here?
The product includes protease, protease 3.0, and protease 6.0—all versions of the same enzyme designed to break down proteins. The numbers likely refer to different potencies or forms, but all work similarly and have the same safety profile.
Will this help with bloating or gas from vegetables?
This blend includes alpha-galactosidase and hemicellulase, which target the complex carbohydrates in beans and cruciferous vegetables that often cause gas. However, we don't have clinical evidence that these ingredients work for that—they're included because of their enzyme function, but the supporting studies aren't in our data.
Is there anything else in this capsule besides the active enzymes?
Yes—the inactive ingredients are microcrystalline cellulose, rice flour, magnesium stearate, and cellulose. These are standard fillers and binders that hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13 label
Sources

Sources & How We Checked

Full Spectrum MD-Formulated, Plant-Based Digestive Enzymes PBDE13's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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