Moringa Oleifera Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Moringa Oleifera against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Moringa Oleifera is a dietary supplement by LEAN Nutraceuticals with 1 active ingredient. Its ingredients are commonly taken for nutritional supplement, blood sugar support, cholesterol support.Based on those ingredients, 869 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Moringa oleifera extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Moringa Oleifera by LEAN Nutraceuticals
Ask about any prescription or over-the-counter medication and we check it for interactions with Moringa Oleifera by LEAN Nutraceuticals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Moringa Oleifera by LEAN Nutraceuticals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This capsule contains one active ingredient: moringa oleifera extract. Moringa is a plant used traditionally to provide nutrients and support general wellness.
The inactive ingredients are vegetable cellulose (the capsule material), magnesium stearate, and silicon dioxide — standard capsule fillers.
Does it work?
Couldn't assess
The evidence we hold does not establish that moringa is effective for any of the conditions it's marketed for — iron deficiency anemia, asthma, athletic performance, diabetes, HIV/AIDS, or high cholesterol. The rating for all of these is insufficient reliable evidence.
That doesn't mean moringa doesn't work; it means the data strong enough to confirm benefit isn't available in our records.
How safe is it?
Well-documented data
Moringa leaf products appear generally well tolerated when used as food, but high-quality safety studies are limited. The most common side effect is transient diarrhea — in one clinical trial, 25% of participants taking 8 grams daily experienced it.
Rare serious effects include allergic reactions and Stevens-Johnson syndrome (a severe skin reaction), though these are uncommon. Do not use medicinal amounts of moringa root or root bark — safety data are lacking, and these parts may stimulate the uterus.
Moringa is traditionally used to boost milk supply, but safety has not been well studied, so use caution if you're breastfeeding. For pregnancy, the data show conflicting ratings: possibly safe in some contexts and possibly unsafe in others.
Talk with your doctor or pharmacist before using moringa if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking moringa, double-check levothyroxine (Synthroid, others) with your pharmacist — moringa may weaken its effect. Also confirm CYP3A4 substrates (a large group of liver-metabolized drugs), P-glycoprotein substrates, antidiabetes drugs, and CYP1A2 substrates.
Your own pharmacist or doctor can tell you whether you take any of these.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Moringa is a single-ingredient supplement with limited established effectiveness for the conditions it's promoted for and documented interactions with thyroid medication, liver-metabolized drugs, and possibly antidiabetes medicines. If you take prescription medications — especially thyroid hormone or anything broken down by your liver — check with your own doctor or pharmacist before adding this.
The supplement is generally well tolerated, but diarrhea and rare allergic reactions have been reported.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Moringa Oleifera, straight from the product label.
| Brand | LEAN Nutraceuticals |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Dec 18, 2021 |
| DSLD ID | 257352 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Moringa Oleifera by LEAN Nutraceuticals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Moringa oleifera extract | 1200 mg | -- |
Other ingredients: Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two (2) veggie capsules daily. For best results take 20-30 minutes before a meal with 8 oz. of water, or as directed by your Healthcare Professional. Discontinue use if not well tolerated.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Seals/Symbols
GMP Good Manufacturing Practice
Made in USA
Formulation
Manufactured in an FDA Inspected Facility
Appetite Suppressant Stimulant-Free Veggie Capsules 100% Natural guarantee
Stimulant free appetite suppressant Helps reduce cravings & unhealthy snacking Improves energy level & metabolism Reduces stress level
General Statements
Please recycle this packaging
Formula
Moringa oleifera extract
30 day supply
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Moringa Oleifera by LEAN Nutraceuticals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Moringa Oleifera by LEAN Nutraceuticals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Moringa oleifera extract
Interacts with869 drugs
Moringa is a nutrient-rich plant whose leaves are widely used as a food and supplement, especially in parts of the world where malnutrition is common....
Moringa oleifera extract monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Moringa Oleifera by LEAN Nutraceuticals Drug Interactions
HelloPharmacist Interaction Report
Moringa Oleifera by LEAN Nutraceuticals interacts with several medication types through its single active ingredient, moringa extract.
The most serious documented interaction is Moderate severity with levothyroxine (Synthroid and others), a thyroid hormone replacement — moringa may reduce how well your body converts the active form of thyroid hormone, potentially weakening the drug's effect.
Read the full breakdown — every affected drug type, severity by severity
Moringa also has Moderate interactions with two other medication categories. It may unpredictably raise or lower levels of CYP3A4 substrates — a broad group of drugs broken down by your liver's CYP3A4 enzyme — because research shows conflicting evidence on whether moringa inhibits or speeds up that enzyme.
Additionally, moringa may increase blood levels of P-glycoprotein substrates, a group of medications transported out of cells by a protein pump that moringa appears to block in lab studies, though this hasn't yet been confirmed in people.
Minor interactions are documented with antidiabetes drugs (moringa may add to their blood-sugar-lowering effect, though human evidence is inconsistent) and CYP1A2 substrates (moringa may decrease their levels). A pharmacokinetic study found no change in nevirapine (an HIV medication) levels when taken with moringa, so that interaction is considered unlikely to matter clinically.
AltogetherIf you take any prescription medication — especially thyroid hormone, HIV drugs, or anything metabolized by your liver — run it through the medication checker on this page before starting moringa, then confirm with your own doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Moringa Oleifera?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Moringa Oleifera interact with 869 drugs. Click any drug to see the details.
1 of the 1 ingredient in Moringa Oleifera interact with drugs. Each result below shows which ingredient is responsible. Moringa oleifera extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Moringa Oleifera — through 1 ingredient. Tap an ingredient for the detail:
Moringa Oleifera ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Moringa Oleifera Extract + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Moringa Oleifera with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Moringa oleifera extract
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, moringa might increase or decrease levels of CYP3A4 substrates.
Some in vitro research suggests that moringa inhibits cytochrome P450 3A4 (CYP3A4). However, other in vitro research suggests that moringa extract induces CYP3A4 enzymes. A pharmacokinetic study in patients with HIV shows no change in the pharmacokinetics of nevirapine, which is partially metabolized by CYP3A4, when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
Levothyroxine (Synthroid, Others)
Theoretically, moringa leaf can antagonize the effects of levothyroxine.
Animal research suggests that moringa aqueous leaf extract might reduce serum triiodothyronine (T3) concentrations by inhibiting the peripheral conversion of thyroxine (T4) to T3.
P-Glycoprotein Substrates
Theoretically, moringa leaf extract might increase the levels and clinical effects of P-glycoprotein substrates.
In vitro research shows that moringa leaf extract inhibits renal P-glycoprotein transport activity. So far, this reaction has not been reported in humans.
Antidiabetes Drugs
Theoretically, moringa might have additive effects when used with antidiabetes drugs; however, research is conflicting.
Animal research shows that moringa can lower blood glucose levels. However, research in humans has not shown consistent blood glucose lowering effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, moringa might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that moringa extract induces CYP1A2 enzymes.
Nevirapine (Viramune)
Moringa leaf is unlikely to have a clinically significant interaction with nevirapine.
Nevirapine is partially metabolized by cytochrome P450 3A4 (CYP3A4). In vitro evidence suggests that moringa inhibits CYP3A4. However, a pharmacokinetic study in patients with HIV shows no change in nevirapine pharmacokinetics when administered concomitantly with moringa leaf powder 1.85 grams daily for 14 days.
Brand information
Manufacturer and brand details for Moringa Oleifera, from the product label.
LEAN Nutraceuticals
See all LEAN Nutraceuticals products- Name
- Lean Nutraceuticals
- Street Address
- 902 S. Randall Rd., Suite 300C
- City
- St. Charles
- State
- IL
- ZipCode
- 60174
- Phone Number
- (855) 382-4296
- Web Address
- www.leannutraceuticals.com
Moringa Oleifera by LEAN Nutraceuticals: Common Questions
Does Moringa Oleifera by LEAN Nutraceuticals interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Moringa Oleifera’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Moringa Oleifera's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Moringa 23 references
- Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. PubMed
- Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000;41:319-23. PubMed
- Jaiswal D, Kumar Rai P, Kumar A, et al. Effect of Moringa oleifera Lam. leaves aqueous extract therapy on hyperglycemic rats. J Ethnopharmcol 2009;123:392-6. PubMed
- Bour S, Visentin V, Prevot D, et al. Effects of oral administration of benzylamine on glucose tolerance and lipid metabolism in rats. J Physiol Biochem 2005;61:371-9. PubMed
- Iffiu-Soltesz Z, Wanecq E, Lomba A, et al. Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice. Pharmacol Res 2010;61:355-63. PubMed
- Monera TG, Wolfe AR, Maponga CC, et al. Moringa oleifera leaf extracts inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2008;2:379-83.
- Estrella M, Mantaring J, David G, Taup M. A double blind, randomised controlled trial on the use of malunggay (Moringa oleifera) for augmentation of the volume of breastmilk among non-nursing mothers of preterm infants. Philipp J Pediatr 2000;49:3-6.
- Morton, J. F. The Horseradish Tree, Moringa Pterygosperma (Moringaceae) - a boon to arid lands? Economic Botany 1991;45:318-333. DOI
- Espinosa-Kuo CL. A Randomized Controlled Trial on the Use of Malunggay (Moringa oleifera) for Augmentation of the Volume of Breastmilk Among Mothers of Term Infants. Filipino Family Physician. 2005;43(1):26-33.
- King JS, Raguindin PFN, Dans LF. Moringa oleifera (Malunggay) as a Galactagogue for Breastfeeding Mothers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Philipp J Pediatr 2013;61(2):34-42.
- Singh D, Choudhury S, Singh TU, Garg SK. Pharmacodynamics of uterotonic effect of Moringa oleifera flowers extract. J Vet Pharmcol Toxicol 2008;7(1-2):12-15.
- William F, Lakshminarayanan S, Chegu H. Effect of some Indian vegetables on the glucose and insulin response in diabetic subjects. International Journal of Food Sciences and Nutrition 1993;44(3): 191-195. DOI: 10.3109/09637489309017439 DOI
- Monera-Penduka TG, Maponga CC, Wolfe AR, Wiesner L, Morse GD, Nhachi CF. Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study. AIDS Res Ther. 2017;14:12. doi: 10.1186/s1 PubMed
- Witharana EWRA, Wijetunga WMGASTB, Wijesinghe SKJ. Stevens - Johnson syndrome (SJS) following murunga leaf (Moringa oleifera) consumption. Ceylon Med J 2018;63(4):188-9.
- Nur R, Demak IPK, Radhiah S, Rusydi M, Mantao E, Larasati RD. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women. Enferm Clin. 2020;30 Suppl 4:79-82. DOI
- Taweerutchana R, Lumlerdkij N, Vannasaeng S, Akarasereenont P, Sriwijitkamol A. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study. Evid Based Complement Alternat M
- Sumiaty, Tahir A, Burhanuddin B, Nurhaedar J, Veni H. The effect of moringa leaves on pregnancy on growth and morbidity of 6-11 month. Enferm Clin. 2020;30 Suppl 4:104-108. DOI
- Ulmy MN, Tahir A, Arsunan AA, Burhanuddin B, Veni H. Effect of moringa leaves during pregnancy on growth and morbidity in 0-5 months. Enferm Clin. 2020;30 Suppl 4:61-65. DOI
- Amaeze O, Marques ES, Wei W, et al. Evaluation of Nigerian Medicinal Plants Extract on Human P-glycoprotein and Cytochrome P450 Enzyme Induction: Implications for Herb-drug Interaction. Curr Drug Metab. 2021;22(14):1103-1113. PubMed
- Ebhohon E, Miller D. Moringa Oleifera leaf extract induced pulmonary embolism-a case report. Int J Emerg Med 2022;15(1):16. PubMed
- Basri H, Hadju V, Zulkifli A, Syam A, Indriasari R. Effect of Moringa oleifera supplementation during pregnancy on the prevention of stunted growth in children between the ages of 36 to 42 months. J Public Health Res 2021;10(2):2207.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Amsler E, Mahevas T, Soria A, Barbaud A. Fixed food eruption to Moringa oleifera. Contact Dermatitis 2023;89(4):301-302.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC