Gallbladder Formula Ingredients & Drug Interactions
by Dr. Berg
What is this page for?
First and foremost: checking Gallbladder Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gallbladder Formula is a dietary supplement by Dr. Berg with 8 active ingredients. Its ingredients are commonly taken for low stomach acid (hypochlorhydria), bloating and gas, indigestion.Based on those ingredients, 2,026 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm, Betaine Hydrochloride, Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gallbladder Formula by Dr. Berg
Ask about any prescription or over-the-counter medication and we check it for interactions with Gallbladder Formula by Dr. Berg — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gallbladder Formula by Dr. Berg
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains eight active ingredients: betaine hydrochloride, choline, pepsin, ox bile extract, pancreatin 4X, slippery elm, stone root, and bile salts, conjugated. Betaine hydrochloride increases stomach acidity, while choline is a nutrient that plays a role in many body processes.
Pepsin, pancreatin, ox bile, and bile salts are digestive substances, and slippery elm and stone root are herbal ingredients. The inactive ingredients are silica, magnesium stearate, and vegetable capsule.
These are non-active components used in the capsule's make-up.
Does it work?
Insufficient evidence
Every rated condition for betaine hydrochloride, slippery elm, and most of choline's uses is rated Insufficient Reliable Evidence To Rate, so we cannot say these ingredients work for those purposes. For choline, athletic performance is rated Possibly Ineffective.
Pepsin, stone root, ox bile extract, pancreatin 4X, and bile salts, conjugated have no effectiveness ratings in the data we hold.
How safe is it?
Well-documented data
Betaine hydrochloride may irritate the stomach and may cause heartburn. Our safety notes say it is not safe for people with ulcers, gastritis, or true acid reflux.
Its own pregnancy entry has no data on file, so talk with your doctor or pharmacist about pregnancy or breastfeeding. Choline is generally well tolerated in food amounts.
At higher doses it can cause fishy body odor, nausea, diarrhea, or vomiting, and the tolerable upper intake level is 3.5 grams daily. Its pregnancy and lactation entry is rated Likely Safe, but supplement doses should follow your doctor's advice.
Slippery elm can cause contact dermatitis, and large amounts of stone root can irritate the intestines.
Meds to double-check
Moderate interaction found
Double-check oral medications first, since slippery elm is rated Moderate for possibly reducing how well they are absorbed. Next, check H2-blockers, antacids, proton pump inhibitors (PPIs), and atropine, all rated Minor, because betaine hydrochloride and choline may reduce their effects.
Ox bile extract, pancreatin 4X, and bile salts, conjugated could not be checked, so review those with your own pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be of interest to adults who are looking for digestive support and understand that the evidence for its ingredients is limited. People with ulcers, gastritis, or acid reflux, and anyone taking H2-blockers, antacids, PPIs, atropine, or any oral medication, should be careful.
Talk it over with your own doctor or pharmacist before you start, especially if you are pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gallbladder Formula, straight from the product label.
| Brand | Dr. Berg |
|---|---|
| Barcode (UPC) | 013964699623 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2024 |
| DSLD ID | 316064 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gallbladder Formula by Dr. Berg, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Betaine Hydrochloride | 400 mg | -- |
| Choline | 40 mg | -- |
| Pepsin | 60 mg | -- |
| Ox Bile extract | 200 mg | -- |
| Pancreatin 4X | 200 mg | -- |
| Slippery Elm | 40 mg | -- |
| Stone Root | 100 mg | -- |
| Bile Salts, Conjugated | 100 mg | -- |
Other ingredients: Silica, Magnesium Stearate, Vegetable Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 2 capsules per day with a meal.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with known medical conditions should consult a physician before using this or any dietary supplement.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place, with a lid.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
To reorder: shop.drberg.com (800) 816-8184
Formulation
Extra Strength
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Dr. Berg The knowledge doc
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gallbladder Formula by Dr. Berg label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gallbladder Formula by Dr. Berg
These are the 8 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Betaine Hydrochloride
Interacts with36 drugs
Betaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is l...
Betaine Hydrochloride monograph & interactionsCholine
Interacts with16 drugs
Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...
Choline monograph & interactionsPepsin
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Pepsin monograph & interactionsOx Bile extract
Pancreatin 4X
Slippery Elm
Interacts with2,022 drugs
Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...
Slippery Elm monograph & interactionsStone Root
No knowninteractions
Stone root is a North American herb traditionally used for hemorrhoids, urinary complaints, and digestive issues. There is very little modern scientif...
Stone Root monograph & interactionsBile Salts, Conjugated
Other (inactive) ingredients: Silica, Magnesium Stearate, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.
Gallbladder Formula by Dr. Berg Drug Interactions
HelloPharmacist Interaction Report
Dr.
Berg's Gallbladder Formula can interact with some medications, through its betaine hydrochloride, choline, and slippery elm content. The most serious interaction we have is a Moderate one with slippery elm and oral drugs.
Its mucilage may interfere with how orally taken medications are absorbed, which could slow absorption and lower the amount of drug in your blood. Altogether, these interactions span 2,027 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Betaine hydrochloride raises stomach acidity, so it could weaken the effects of H2-blockers, antacids, and proton pump inhibitors (PPIs), each rated Minor. Choline may reduce the effects of atropine, rated Minor, based on animal research showing it can lower atropine's effect on brain acetylcholine levels.
We could not check Ox Bile extract, Pancreatin 4X, or Bile Salts, Conjugated, because we hold no interaction data for them. Pepsin and stone root were checked, and no interactions are documented for them in our data, though that is not a guarantee none exist.
Search your exact medications with the search tool on this page, and confirm the details with your own doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Gallbladder Formula?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gallbladder Formula interact with 2,026 drugs. Click any drug to see the details.
3 of the 8 ingredients in Gallbladder Formula interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Betaine Hydrochloride Choline
Brompheniramine, PhenylpropanolamineDimetapp, E N T, Porcupine
How Brompheniramine, Phenylpropanolamine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Brompheniramine, Phenylpropanolamine interactionBrompheniramine, PseudoephedrineAllent, BPM PSEH 08, Bromfed, Bromfed PD, Bromfenex, Bromfenex PD +12 more
How Brompheniramine, Pseudoephedrine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Brompheniramine, Pseudoephedrine interactionBuclizineBucladin-S Softab
How Buclizine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buclizine interactionBudenosidePulmicort Flexhaler, Pulmicort Turbuhaler
How Budenoside interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Budenoside interactionBudesonideEntocort EC, Eohilia, Pulmicort, Tarpeyo, Uceris
How Budesonide interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Budesonide interactionBudesonide, FormoterolSymbicort
How Budesonide, Formoterol interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Budesonide, Formoterol interactionBumetanideBurinex
How Bumetanide interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bumetanide interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bumetanide (oral) interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bumetanide, Potassium interactionBupivacaineExparel, Marcaine, Posimir
How Bupivacaine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bupivacaine interactionBuprenorphineBrixadi, Butrans, Sublocade, Subutex
How Buprenorphine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buprenorphine interactionBuprenorphine Hydrochloride, Naloxone HydrochlorideBunavail
How Buprenorphine Hydrochloride, Naloxone Hydrochloride interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buprenorphine Hydrochloride, Naloxone Hydrochloride interactionBuprenorphine, NaloxoneCassipa, Zubsolv
How Buprenorphine, Naloxone interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buprenorphine, Naloxone interactionBuprenorphine/naloxoneSuboxone
How Buprenorphine/naloxone interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buprenorphine/naloxone interactionBupropionAplenzin, Forfivo XL, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban
How Bupropion interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bupropion interactionBupropion, NaltrexoneContrave
How Bupropion, Naltrexone interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Bupropion, Naltrexone interactionBuproprion, DextromethorphanAuvelity
How Buproprion, Dextromethorphan interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buproprion, Dextromethorphan interactionBuspironeBuSpar
How Buspirone interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Buspirone interactionBusulfanBusulfex, Myleran
How Busulfan interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Busulfan interactionButabarbital SodiumButisol Sodium, Sarisol #2
How Butabarbital Sodium interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butabarbital Sodium interactionButabarbital, Hyoscyamine, PhenazopyridinePyridium Plus
How Butabarbital, Hyoscyamine, Phenazopyridine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butabarbital, Hyoscyamine, Phenazopyridine interactionButabarbital, Phenobarbital, SecobarbitalS.B.P.
How Butabarbital, Phenobarbital, Secobarbital interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butabarbital, Phenobarbital, Secobarbital interactionButalbital, Phenobarbital, SecobarbitalTribarb
How Butalbital, Phenobarbital, Secobarbital interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butalbital, Phenobarbital, Secobarbital interactionButaperazineRepoise
How Butaperazine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butaperazine interactionButenafineMentax
How Butenafine interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butenafine interactionButoconazoleGynazole
How Butoconazole interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butoconazole interactionButorphanolStadol
How Butorphanol interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Butorphanol interactionCabergolineDostinex
How Cabergoline interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cabergoline interactionCabotegravir SodiumVocabria
How Cabotegravir Sodium interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cabotegravir Sodium interactionCabozantinibCometriq
How Cabozantinib interacts with Gallbladder Formula — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Cabozantinib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gallbladder Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Betaine Hydrochloride
Antacids
Betaine hydrochloride increases stomach acidity and could decrease the effects of antacids.
In human research, betaine hydrochloride increases stomach acidity. Antacids are taken to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with antacids might decrease the effects of the antacids.
H2-Blockers
Betaine hydrochloride increases stomach acidity and could decrease the effects of H2-blockers.
In human research, betaine hydrochloride increases stomach acidity. H2-blockers are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with H2-blockers might decrease the effects of H2-blockers.
Proton Pump Inhibitors (Ppis)
Betaine hydrochloride increases stomach acidity and could decrease the effects of PPIs.
In human research, betaine hydrochloride increases stomach acidity. PPIs are used to decrease stomach acidity. Theoretically, taking betaine hydrochloride along with PPIs might decrease the effects of PPIs
Choline
Atropine
Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.
Brand information
Manufacturer and brand details for Gallbladder Formula, from the product label.
Dr. Berg
- Name
- Dr. Berg Nutritionals
- Street Address
- 4501 Ford Avenue
- City
- Alexandria
- State
- VA
- ZipCode
- 22302
- Phone Number
- 800-816-8184
- Web Address
- shop.drberg.com
Gallbladder Formula by Dr. Berg: Common Questions
Does Gallbladder Formula by Dr. Berg interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is choline safe during pregnancy?
Does this product work for constipation?
Why might choline make me smell fishy?
What does betaine hydrochloride do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gallbladder Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gallbladder Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Betaine Hydrochloride
Interacts with 36 drugsBetaine hydrochloride is a supplement used to temporarily increase stomach acid in people who may have low acid levels. Evidence for its benefits is limited and mostly based on tradition rat...
Read the full Betaine Hydrochloride monograph → Herb & supplement monographCholine
Interacts with 16 drugsCholine is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...
Read the full Choline monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographSlippery Elm
Interacts with 2,022 drugsSlippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...
Read the full Slippery Elm monograph → Herb & supplement monographStone Root
Stone root is a North American herb traditionally used for hemorrhoids, urinary complaints, and digestive issues. There is very little modern scientific evidence to confirm it works for any...
Read the full Stone Root monograph →Sources & How We Checked
Gallbladder Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 23 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Betaine Hydrochloride 2 references
- Yago MR, Frymoyer A, Benet LZ, Smelick GS, Frassetto LA, Ding X, Dean B, Salphati L, Budha N, Jin JY, Dresser MJ, Ware JA. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. AAPS J. 2014 PubMed
- Yago MR, Frymoyer AR, Smelick GS, Frassetto LA, Budha NR, Dresser MJ, Ware JA, Benet LZ. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Mol Pharm. 2013 Nov 4;10(11):4032-7. PubMed
See these in context on the Betaine Hydrochloride monograph →
Choline 14 references
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
- Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
- Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
- Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
- Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
- Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
- Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
- Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
- Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
- Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
- Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
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See these in context on the Proteolytic Enzymes (proteases) monograph →
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
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- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Stone Root 1 reference
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
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