No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Gelatin 650 mg Ingredients & Drug Interactions

by Sundown Naturals

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Gelatin 650 mg is a dietary supplement by Sundown Naturals with 2 active ingredients. Its ingredients are commonly taken for joint and bone health, skin, hair, and nail support, source of dietary protein.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Gelatin 650 mg by Sundown Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gelatin at 650 mg per capsule. Gelatin is a protein derived from collagen, commonly used in supplements and foods as a structural ingredient.

The capsule also contains vegetable magnesium stearate as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gelatin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Support for nails, hair, and skin health.
  • We looked for evidence on: Aging skin, Brittle nails, Wrinkled skin, Hair health, Skin elasticity.
  • The closest evidence on file: Gelatin is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Gelatin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails, Wrinkled skin.

The evidence for gelatin is mixed and limited. For diarrhea, it's rated possibly ineffective — meaning the data we hold suggests it's unlikely to help.

For aging skin, brittle nails, beta-thalassemia, and uterine fibroids, there isn't enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Gelatin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gelatin is widely used in food and is generally well tolerated at food amounts. Common side effects when taken orally include belching, bloating, indigestion (dyspepsia), and an unpleasant taste or sensation of heaviness in the stomach.

Rare but serious allergic reactions are possible — gelatin can cause hives, swelling of the face or throat, wheezing, a dangerous drop in blood pressure, and in severe cases anaphylaxis. If you have a known gelatin allergy or have reacted to gelatin-containing vaccines or medicines, avoid this product.

At food amounts gelatin is considered safe during pregnancy and breastfeeding, but because we hold no specific data on supplement doses in pregnancy or while nursing, talk with your doctor or pharmacist before using this product at supplement strength if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Gelatin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for the ingredients we could check in this product. That said, it's always smart to mention any new supplement to your pharmacist when you pick up prescriptions.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Gelatin is generally well tolerated and has no known medication interactions, but the evidence that it works for most claimed uses is weak or absent. It's most helpful if you're simply looking for a source of dietary gelatin — not as a targeted remedy.

If you have a gelatin allergy or history of allergic reactions to gelatin-containing vaccines, skip it. Talk to your pharmacist or doctor if you're pregnant, nursing, or unsure whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gelatin 650 mg, straight from the product label.

Brand Sundown Naturals
Barcode (UPC) 030768005368
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 26, 2014
DSLD ID 30220
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gelatin 650 mg by Sundown Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
030768005368
IngredientAmount% DV
Protein1 Gram(s)2%
Gelatin1300 mg--

Other ingredients: Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Eight (8) capsules provide 80 grains of edible gelatin.

Precautions

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF REACH OF CHILDREN.

Seals/Symbols

{Bottle} PLEASE RECYCLE

GUARANTEED LABORATORY TESTED QUALITY

General Statements

As a reminder, discuss the supplements and medications you take with your health care providers.

Smart Facts An active lifestyle, on-the-run nutrition, harsh detergents and chemicals - all can have an effect on the health of your nails, hair, and skin. Gelatin is one of the raw materials for collagen, the building block for strong nails and healthy hair and skin.*

Promotes Healthy Hair, Skin & Nails*

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

DIRECTIONS: FOR ADULTS, TAKE TWO (2) CAPSULES AFTER EACH MEAL AND AT BEDTIME.

FDA Statement of Identity

DIETARY SUPPLEMENT

General

Prod. No. 44611 03B B780 CAB

Brand IP Statement(s)

(C)2012

Formulation

No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Storage

STORE IN A DRY PLACE AND AVOID EXCESSIVE HEAT.

See for yourself

Gelatin 650 mg by Sundown Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gelatin 650 mg by Sundown Naturals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

1 Gram(s) per serving

Gelatin

No known
interactions
1300 mg per serving

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most heal...

Gelatin monograph & interactions

Other (inactive) ingredients: Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gelatin 650 mg by Sundown Naturals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Gelatin 650 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Gelatin 650 mg, from the product label.

Pharmacist Counseling Corner

Gelatin 650 mg by Sundown Naturals: Common Questions

Does Gelatin 650 mg by Sundown Naturals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Gelatin 650 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Gelatin 650 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's gelatin actually for?
Gelatin is a protein used in supplements and food as a structural ingredient. This product has been studied for things like diarrhea, skin aging, and brittle nails, but the evidence that it works for most of these is limited or absent.
Will this upset my stomach?
Some people notice belching, bloating, indigestion, or a heavy feeling in the stomach when they take gelatin capsules. Most people tolerate it fine, but if you have a sensitive stomach, start with a smaller dose or take it with food.
Can I take this if I'm allergic to gelatin?
No. Gelatin allergies, though rare, can cause serious reactions including hives, swelling, wheezing, and in severe cases anaphylaxis. If you've reacted to gelatin-containing vaccines or medicines in the past, avoid this product.
Is it safe to take while I'm pregnant or breastfeeding?
At food amounts, gelatin is considered safe in both pregnancy and breastfeeding. We don't have specific data on supplement doses at this strength, though, so talk with your doctor or pharmacist before starting if you're pregnant or nursing.
Does this actually help with brittle nails or skin?
There isn't enough reliable evidence to say either way. The product is rated as having insufficient evidence for both of those uses, so results are unpredictable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gelatin 650 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gelatin 650 mg label
Go deeper

The Full Monographs Behind Gelatin 650 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Gelatin 650 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gelatin 11 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Schwick HG, Heide K. Immunochemistry and immunology of collagen and gelatin. Bibl Haematol 1969;33:111-25. PubMed
  3. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99. PubMed
  4. Kelso JM. The gelatin story. J Allergy Clin Immunol 1999;103:200-2.
  5. Nakayama T, Aizawa C, Kuno-Sakai H. A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allerg PubMed
  6. Sakaguchi M, Inouye S. Anaphylaxis to gelatin-containing rectal suppositories. J Allergy Clin Immunol 2001;108:1033-4. PubMed
  7. PDR Electronic Library. Montvale, NJ: Medical Economics Company, Inc., 2001.
  8. de la Fuente Tornero E, Vega Castro A, de Sierra Hernández PÁ, et al. Kounis syndrome during anesthesia: Presentation of indolent systemic mastocytosis: A case report. A Case Rep. 2017;8(9):226-228. PubMed
  9. Ventura Spagnolo E, Calapai G, Minciullo PL, Mannucci C, Asmundo A, Gangemi S. Lethal anaphylactic reaction to intravenous gelatin in the course of surgery. Am J Ther. 2016;23(6):e1344-e1346. PubMed
  10. Li Y, He H, Yang L, Li X, Li D, Luo S. Therapeutic effect of Colla corii asini on improving anemia and hemoglobin compositions in pregnant women with thalassemia. Int J Hematol. 2016;104(5):559-565. PubMed
  11. Coury JR, Skaggs KF, Marciano GF, et al. Intraoperative Anaphylaxis to the Bovine Flowable Gelatin Matrix: A Report of 2 Cases. JBJS Case Connect 2022;12(1). PubMed

See these in context on the Gelatin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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