No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 8 ingredients. Check your meds →
Dietary supplement

Gluten Bloc Ingredients & Drug Interactions

by Natural Balance

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Gluten Bloc is a dietary supplement by Natural Balance with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Gluten Bloc by Natural Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • “GlutenGuard(TM) Enzyme Blend” is a proprietary blend — the label gives one combined amount (350 mg) without saying how much of each component you get.

Gluten Bloc contains eight active ingredients, all of them digestive enzymes designed to break down carbohydrates and proteins. The product includes Amylase, Protease, Peptidase, Glucoamylase, Beta-Glucanase, Hemicellulase, Dipeptidyl Peptidase-IV, and Aminopeptidase N, plus a proprietary blend called GlutenGuard™ Enzyme Blend.

These inactive ingredients also include Rice Flour, Maltodextrin, Gelatin Capsule, Silica, and Stearic Acid.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive enzyme support for food comfort.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we hold do not include effectiveness ratings for any of the active ingredients in Gluten Bloc. We cannot tell you whether the evidence supports its use for gluten digestion or any other purpose based on the data available to us.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease, the one ingredient we have safety data for, is generally well tolerated by most adults but may cause digestive upset or allergic reactions in some people. Because protease is commonly found in laundry detergents and cleaning products, rare cases of allergic reactions have been reported from occupational exposure, including allergic rhinitis or asthma from airborne exposure in workplace settings.

During pregnancy, safety has not been established, so Protease is best avoided unless prescribed; during breastfeeding, there is little safety data, so medical advice is recommended before use. We hold no safety data for the other seven active ingredients.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, because we cannot verify seven of the eight active ingredients against medications, check your exact drugs with the search tool on this page or run the ingredient list by your pharmacist before taking Gluten Bloc.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Gluten Bloc is a multi-enzyme product aimed at helping with gluten digestion. If you're pregnant, breastfeeding, or take any medications, talk with your doctor or pharmacist before starting — we couldn't check most of the ingredients here against drug interactions, and the one we did check (Protease) has some cautions around allergic reactions.

Your own healthcare provider can weigh whether this product makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gluten Bloc, straight from the product label.

Brand Natural Balance
Barcode (UPC) 047868308893
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Apr 24, 2015
DSLD ID 44888
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gluten Bloc by Natural Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
047868308893
IngredientAmount% DV
Amylase14000 DU--
Protease40000 HUT--
Peptidase20000 HUT--
Glucoamylase18 AGU--
Beta-Glucanase20 BGU--
Hemicellulase500 HCU--
Dipeptidyl Peptidase-IV500 DPP-IV--
GlutenGuard(TM) Enzyme Blend350 mg--
Aminopeptidase N6000 HUT--

Other ingredients: Rice Flour, Maltodextrin, Gelatin Capsule, Silica, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Advanced Digestive Aid - Fast-Acting & Soothing - Digestive Enzyme Support - Reliable Comfort

Enjoy the Foods you Love!

FDA Statement of Identity

Dietary Supplement

Precautions

WARNING: Do not use if safety seal is broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product, especially if you have sever gluten sensitivity.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take two capsules daily with a meal.

Storage

Store in a cool, dry place.

General

1683001 1214

See for yourself

Gluten Bloc by Natural Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Gluten Bloc by Natural Balance

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

GlutenGuard(TM) Enzyme Blend

350 mg per serving
  • › Amylase
  • Protease
  • › Peptidase
  • › Glucoamylase
  • › Beta-Glucanase
  • › Hemicellulase
  • › Dipeptidyl Peptidase-IV
  • › Aminopeptidase N

Other (inactive) ingredients: Rice Flour, Maltodextrin, Gelatin Capsule, Silica, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gluten Bloc by Natural Balance Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Gluten Bloc. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Gluten Bloc, from the product label.

Natural Balance

See all Natural Balance products
Name
Natural Balance
City
Tulsa
State
OK
ZipCode
74128
Phone Number
800-538-5888
Web Address
www.naturalbalance.com
Pharmacist Counseling Corner

Gluten Bloc by Natural Balance: Common Questions

Does Gluten Bloc by Natural Balance interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Gluten Bloc. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Gluten Bloc contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Gluten Bloc if I'm pregnant?
Safety data for most of the ingredients in this product isn't established. Protease, the one ingredient we have data for, is best avoided during pregnancy unless prescribed. Talk with your doctor or pharmacist about whether this product is right for you.
Is it safe to take Gluten Bloc while breastfeeding?
There is little safety data during breastfeeding for Protease and no safety data for the other active ingredients. Medical advice is recommended before use. Check with your doctor or pharmacist.
What does Protease do in this product?
Protease is a digestive enzyme that breaks down proteins. In Gluten Bloc, it's included as part of the enzyme blend to support digestion.
Can Protease cause allergic reactions?
Yes. Protease may cause digestive upset or allergic reactions in some people. Rarely, occupational exposure to similar enzymes has triggered allergic rhinitis or asthma; most users tolerate it well, but tell your doctor if you have a history of enzyme or detergent sensitivities.
Does this product have fillers?
Yes. Gluten Bloc contains inactive ingredients including Rice Flour, Maltodextrin, Gelatin Capsule, Silica, and Stearic Acid.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gluten Bloc is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gluten Bloc label
Sources

Sources & How We Checked

Gluten Bloc's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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